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Medicine

D-Index
85
Citations
22666
World Ranking
14741
National Ranking
7455

Overview

Shuyuan Yeh is affiliated with the University of Rochester Medical Center in the United States, focusing on interdisciplinary research that intersects medicine, biochemistry, genetics, and molecular biology. Their work encompasses a broad range of topics within the biomedical sciences, particularly emphasizing cancer research and molecular mechanisms driving disease progression.

The primary fields of study for Yeh include Medicine and Biochemistry, Genetics, and Molecular Biology. Within these, they have contributed extensively to subfields such as Pulmonary and Respiratory Medicine, Molecular Biology, Cancer Research, Surgery, and Oncology. Their research addresses numerous cancer-related topics, including prostate cancer treatment and research, cancer-related molecular mechanisms, circular RNAs in diseases, cancer metabolism involving lipids, bladder and urothelial cancer therapies, ferroptosis linked with cancer prognosis, and microRNA in disease regulation.

Yeh has published in several notable scientific journals. Frequent venues for their work include:

  • The Journal of Urology
  • Cell Death and Disease
  • Oncogene
  • Cancer Letters
  • bioRxiv (Cold Spring Harbor Laboratory)

Some of their recent papers are:

  • "Androgen receptor-regulated circ FNTA activates KRAS signaling to promote bladder cancer invasion," 2020, EMBO Reports
  • "The MAO inhibitors phenelzine and clorgyline revert enzalutamide resistance in castration resistant prostate cancer," 2020, Nature Communications
  • "The miR-92a-2-5p in exosomes from macrophages increases liver cancer cells invasion via altering the AR/PHLPP/p-AKT/β-catenin signaling," 2020, Cell Death and Differentiation
  • "Estrogen receptor α promotes lung cancer cell invasion via increase of and cross-talk with infiltrated macrophages through the CCL2/CCR2/MMP9 and CXCL12/CXCR4 signaling pathways," 2020, Molecular Oncology
  • "Estrogen and G protein-coupled estrogen receptor accelerate the progression of benign prostatic hyperplasia by inducing prostatic fibrosis," 2022, Cell Death and Disease

The scientist has collaborated frequently with colleagues including Chawnshang Chang, Bosen You, Chi-Ping Huang, Edward M. Messing, and Yin Sun. These partnerships reflect ongoing interdisciplinary engagement within their specialized fields.

Yeh's research portfolio contributes to understanding the molecular underpinnings of various cancers, with a notable focus on hormone-related signaling pathways and cellular mechanisms affecting cancer invasiveness and resistance to treatment.

Best Publications

  • Cloning and characterization of a specific coactivator, ARA70, for the androgen receptor in human prostate cells.

    Shuyuan Yeh;Chawnshang Chang

  • From HER2/Neu signal cascade to androgen receptor and its coactivators: A novel pathway by induction of androgen target genes through MAP kinase in prostate cancer cells

    Shuyuan Yeh;Hui Kuan Lin;Hong Yo Kang;Tin Htwe Thin

  • Generation and characterization of androgen receptor knockout (ARKO) mice: An in vivo model for the study of androgen functions in selective tissues

    Shuyuan Yeh;Meng Yin Tsai;Meng Yin Tsai;Qingquan Xu;Xiao Min Mu

  • Infertility with defective spermatogenesis and hypotestosteronemia in male mice lacking the androgen receptor in Sertoli cells

    Chawnshang Chang;Yen-Ta Chen;Yen-Ta Chen;Shauh-Der Yeh;Qingquan Xu

  • Androgen Receptor Roles in Spermatogenesis and Fertility: Lessons from Testicular Cell-Specific Androgen Receptor Knockout Mice

    Ruey Sheng Wang;Shuyuan Yeh;Chii Ruey Tzeng;Chii Ruey Tzeng;Chawnshang Chang

  • Akt suppresses androgen-induced apoptosis by phosphorylating and inhibiting androgen receptor

    Hui-Kuan Lin;Shuyuan Yeh;Hong-Yo Kang;Chawnshang Chang

  • Promotion of Bladder Cancer Development and Progression by Androgen Receptor Signals

    Hiroshi Miyamoto;Zhiming Yang;Yei Tsung Chen;Hitoshi Ishiguro

  • Androgen receptor: an overview.

    Chawnshang Chang;Alan Saltzman;Shuyuan Yeh;Winjing Young

  • Androgen receptor is a tumor suppressor and proliferator in prostate cancer

    Yuanjie Niu;Saleh Altuwaijri;Kuo-Pao Lai;Chun-Te Wu

  • Subfertility and defective folliculogenesis in female mice lacking androgen receptor

    Yueh-Chiang Hu;Peng-Hui Wang;Shuyuan Yeh;Ruey-Sheng Wang

  • From estrogen to androgen receptor: a new pathway for sex hormones in prostate.

    Shuyuan Yeh;Hiroshi Miyamoto;Hiroki Shima;Hiroki Shima;Chawnshang Chang

  • Increased prostate cell proliferation and loss of cell differentiation in mice lacking prostate epithelial androgen receptor.

    Chun-Te Wu;Saleh Altuwaijri;William A. Ricke;Shu-Pin Huang

  • Promotion of agonist activity of antiandrogens by the androgen receptor coactivator, ARA70, in human prostate cancer DU145 cells

    Hiroshi Miyamoto;Shuyuan Yeh;George Wilding;Chawnshang Chang;Chawnshang Chang

  • Androgen Receptor Is a New Potential Therapeutic Target for the Treatment of Hepatocellular Carcinoma

    Weng–Lung Ma;Cheng–Lung Hsu;Cheng–Lung Hsu;Ming–Heng Wu;Chun–Te Wu;Chun–Te Wu

  • Androgen receptor (AR) differential roles in hormone-related tumors including prostate, bladder, kidney, lung, breast and liver.

    C Chang;S O Lee;S Yeh;T M Chang

  • Expression of androgen and oestrogen receptors and its prognostic significance in urothelial neoplasm of the urinary bladder.

    Hiroshi Miyamoto;Jorge L. Yao;Alcides Chaux;Yichun Zheng

  • Androgen Receptor in Sertoli Cell Is Essential for Germ Cell Nursery and Junctional Complex Formation in Mouse Testes

    Ruey Sheng Wang;Ruey Sheng Wang;Shuyuan Yeh;Lu Min Chen;Lu Min Chen;Hung Yun Lin

  • Increased hepatic steatosis and insulin resistance in mice lacking hepatic androgen receptor.

    Hung-Yun Lin;I-Chen Yu;Ruey-Shen Wang;Ruey-Shen Wang;Yei-Tsung Chen

  • Differential effects of spermatogenesis and fertility in mice lacking androgen receptor in individual testis cells.

    Meng Yin Tsai;Shauh Der Yeh;Ruey Sheng Wang;Ruey Sheng Wang;Shuyuan Yeh

  • Androgen Receptor Promotes Hepatitis B Virus–Induced Hepatocarcinogenesis Through Modulation of Hepatitis B Virus RNA Transcription

    Ming Heng Wu;Wen Lung Ma;Wen Lung Ma;Cheng Lung Hsu;Cheng Lung Hsu;Yuh Ling Chen;Yuh Ling Chen

Frequent Co-Authors

Chawnshang Chang
Chawnshang Chang University of Rochester Medical Center
Edward M. Messing
Edward M. Messing University of Rochester Medical Center
Hui Kuan Lin
Hui Kuan Lin Wake Forest University
Henry A. Lardy
Henry A. Lardy University of Wisconsin–Madison
David A. Bushinsky
David A. Bushinsky University of Rochester
Sherry R. Chemler
Sherry R. Chemler University at Buffalo, State University of New York
George J. Netto
George J. Netto University of Alabama at Birmingham
Emmanuel S. Antonarakis
Emmanuel S. Antonarakis University of Minnesota
Jiaoti Huang
Jiaoti Huang Duke University
Hsing Jien Kung
Hsing Jien Kung Taipei Medical University

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