Albert O. Brinkmann

Research.com Recognitions

• 2023 - Research.com Biology and Biochemistry in Netherlands Leader Award

Overview

Best Publications

• A mutation in the ligand binding domain of the androgen receptor of human LNCaP cells affects steroid binding characteristics and response to anti-androgens

  J. Veldscholte;C. Ris-Stalpers;G.G.J.M. Kuiper;G. Jenster

  1208
  Citations

• Targeted disruption of the Insl3 gene causes bilateral cryptorchidism.

  Stephan Zimmermann;Gerd Steding;Judith M. A. Emmen;Albert O. Brinkmann

  787
  Citations

• A polymorphism in the glucocorticoid receptor gene may be associated with an increased sensitivity to glucocorticoids in vivo

  N. A. T. M. Huizenga;J. W. Koper;P. De Lange;H. A. P. Pols

  678
  Citations

• The promoter of the prostate-specific antigen gene contains a functional androgen responsive element.

  P. H. J. Riegman;R. J. Vlietstra;J. A. G. M. van der Korput;A. O. Brinkmann

  671
  Citations

• Domains of the human androgen receptor involved in steroid binding, transcriptional activation, and subcellular localization.

  Guido Jenster;Hetty A. G. M. van der Korput;Cor van Vroonhoven;Theo H. van der Kwast

  652
  Citations

• The androgen receptor in LNCaP cells contains a mutation in the ligand binding domain which affects steroid binding characteristics and response to antiandrogens

  J. Veldscholte;C.A. Berrevoets;C. Ris-Stalpers;G.G.J.M. Kuiper

  577
  Citations

• Two Androgen Response Regions Cooperate in Steroid Hormone Regulated Activity of the Prostate-specific Antigen Promoter (∗)

  Kitty B.J.M. Cleutjens;Conny C.E.M. van Eekelen;Hetty A.G.M. van der Korput;Albert O. Brinkmann

  574
  Citations

• Identification of two transcription activation units in the N-terminal domain of the human androgen receptor.

  Guido Jenster;Hetty A.G.M. van der Korput;Jan Trapman;Albert O. Brinkmann

  535
  Citations

• Cloning, structure and expression of a cDNA encoding the human androgen receptor.

  J. Trapman;P. Klaassen;G.G.J.M. Kuiper;J.A.G.M. van der Korput

  512
  Citations

• The human androgen receptor: domain structure, genomic organization and regulation of expression.

  A.O. Brinkmann;P.W. Faber;H.C.J. van Rooij;G.G.J.M. Kuiper

  468
  Citations

• Mechanisms of androgen receptor activation and function

  A.O Brinkmann;L.J Blok;P.E de Ruiter;P Doesburg

  431
  Citations

• Anti-androgens and the mutated androgen receptor of LNCaP cells: differential effects on binding affinity, heat-shock protein interaction, and transcription activation.

  Jos Veldscholte;Cor A. Berrevoets;Albert O. Brinkmann;J. Anton Grootegoed

  421
  Citations

• Molecular basis of androgen insensitivity.

  Albert O. Brinkmann

  416
  Citations

• Identification of the BclI polymorphism in the glucocorticoid receptor gene: association with sensitivity to glucocorticoids in vivo and body mass index

  Elisabeth F C van Rossum;Jan W Koper;Annewieke W van den Beld;André G Uitterlinden

  412
  Citations

• A Polymorphism in the Glucocorticoid Receptor Gene, Which Decreases Sensitivity to Glucocorticoids In Vivo, Is Associated With Low Insulin and Cholesterol Levels

  Elisabeth F.C. van Rossum;Jan W. Koper;Nannette A.T.M. Huizenga;André G. Uitterlinden

  411
  Citations

• Nuclear import of the human androgen receptor

  G Jenster;J Trapman;A O Brinkmann

  335
  Citations

• Lack of association between five polymorphisms in the human glucocorticoid receptor gene and glucocorticoid resistance

  JW Koper;Ronald Stolk;P deLange;Natm Huizenga

  319
  Citations

• Functional interactions of the AF-2 activation domain core region of the human androgen receptor with the amino-terminal domain and with the transcriptional coactivator TIF2 (transcriptional intermediary factor2).

  Cor A. Berrevoets;Paul Doesburg;Karine Steketee;Jan Trapman

  306
  Citations

• Two polymorphisms in the glucocorticoid receptor gene directly affect glucocorticoid-regulated gene expression.

  Henk Russcher;Pauline Smit;Erica L. T. van den Akker;Elisabeth F. C. van Rossum

  252
  Citations

• The androgen receptor in prostate cancer.

  J. Trapman;A.O. Brinkmann

  138
  Citations