Jan Trapman

Research.com Recognitions

• 2023 - Research.com Biology and Biochemistry in Netherlands Leader Award

Overview

Best Publications

• Androgen receptor activation in prostatic tumor cell lines by insulin-like growth factor-I, keratinocyte growth factor and epidermal growth factor.

  Zoran Culig;Alfred Hobisch;Marcus V. Cronauer;Christian Radmayr

  1393
  Citations

• A mutation in the ligand binding domain of the androgen receptor of human LNCaP cells affects steroid binding characteristics and response to anti-androgens

  J. Veldscholte;C. Ris-Stalpers;G.G.J.M. Kuiper;G. Jenster

  1208
  Citations

• Androgen Receptor Gene Amplification: A Possible Molecular Mechanism for Androgen Deprivation Therapy Failure in Prostate Cancer

  Pasi Koivisto;Juha Kononen;Christian Palmberg;Teuvo Tammela

  974
  Citations

• The promoter of the prostate-specific antigen gene contains a functional androgen responsive element.

  P. H. J. Riegman;R. J. Vlietstra;J. A. G. M. van der Korput;A. O. Brinkmann

  671
  Citations

• Domains of the human androgen receptor involved in steroid binding, transcriptional activation, and subcellular localization.

  Guido Jenster;Hetty A. G. M. van der Korput;Cor van Vroonhoven;Theo H. van der Kwast

  652
  Citations

• The androgen receptor in LNCaP cells contains a mutation in the ligand binding domain which affects steroid binding characteristics and response to antiandrogens

  J. Veldscholte;C.A. Berrevoets;C. Ris-Stalpers;G.G.J.M. Kuiper

  577
  Citations

• Two Androgen Response Regions Cooperate in Steroid Hormone Regulated Activity of the Prostate-specific Antigen Promoter (∗)

  Kitty B.J.M. Cleutjens;Conny C.E.M. van Eekelen;Hetty A.G.M. van der Korput;Albert O. Brinkmann

  574
  Citations

• An Androgen Response Element in a Far Upstream Enhancer Region Is Essential for High, Androgen-Regulated Activity of the Prostate-Specific Antigen Promoter

  Kitty B. J. M. Cleutjens;Hetty A. G. M. van der Korput;Conny C. E. M. van Eekelen;Henri C. J. van Rooij

  554
  Citations

• Frequent Inactivation of PTEN in Prostate Cancer Cell Lines and Xenografts

  Vlietstra Rj;van Alewijk Dc;Hermans Kg;van Steenbrugge Gj

  553
  Citations

• Identification of two transcription activation units in the N-terminal domain of the human androgen receptor.

  Guido Jenster;Hetty A.G.M. van der Korput;Jan Trapman;Albert O. Brinkmann

  535
  Citations

• Cloning, structure and expression of a cDNA encoding the human androgen receptor.

  J. Trapman;P. Klaassen;G.G.J.M. Kuiper;J.A.G.M. van der Korput

  512
  Citations

• The human androgen receptor: domain structure, genomic organization and regulation of expression.

  A.O. Brinkmann;P.W. Faber;H.C.J. van Rooij;G.G.J.M. Kuiper

  468
  Citations

• Mechanisms of androgen receptor activation and function

  A.O Brinkmann;L.J Blok;P.E de Ruiter;P Doesburg

  431
  Citations

• Androgen receptors in endocrine-therapy-resistant human prostate cancer

  T. H. Van Der Kwast;J. Schalken;J. A. Ruizeveld De Winter;C. C. J. Van Vroonhoven

  425
  Citations

• Androgen receptor status in localized and locally progressive hormone refractory human prostate cancer.

  J. A. Ruizeveld De Winter;P. J. A. Janssen;H. M. E. B. Sleddens;M. C. T. Verleun-Mooijman

  421
  Citations

• Androgen receptor expression in human tissues : an immunohistochemical study

  J A Ruizeveld de Winter;J Trapman;M Vermey;E Mulder

  376
  Citations

• TMPRSS2:ERG Fusion by Translocation or Interstitial Deletion Is Highly Relevant in Androgen-Dependent Prostate Cancer, But Is Bypassed in Late-Stage Androgen Receptor–Negative Prostate Cancer

  Karin G. Hermans;Ronald van Marion;Herman van Dekken;Guido Jenster

  335
  Citations

• Nuclear import of the human androgen receptor

  G Jenster;J Trapman;A O Brinkmann

  335
  Citations

• Functional in Vivo Interaction between the Amino-Terminal, Transactivation Domain and the Ligand Binding Domain of the Androgen Receptor†

  Paul Doesburg;Cor W. Kuil;Cor A. Berrevoets;Karine Steketee

  314
  Citations

• The androgen receptor in prostate cancer.

  J. Trapman;A.O. Brinkmann

  138
  Citations