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Molecular Biology

D-Index
65
Citations
17731
World Ranking
1660
National Ranking
840

Overview

Marc Symons is affiliated with the Feinstein Institute for Medical Research in the United States. Their research primarily spans the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with particular focus on Oncology, Pulmonary and Respiratory Medicine, Molecular Biology, Genetics, and Cancer Research.

The main topics covered in Marc Symons' work include:

  • Glioma Diagnosis and Treatment
  • Sarcoma Diagnosis and Treatment
  • Cancer Cells and Metastasis
  • Cancer-related Molecular Pathways
  • Cancer Research and Treatments
  • Lung Cancer Treatments and Mutations
  • Peptidase Inhibition and Analysis

Marc Symons has contributed to several recent papers, reflecting diverse research interests within cancer biology and treatment. Noteworthy publications include:

  • "Signaling Determinants of Glioma Cell Invasion," 2020, published in Advances in Experimental Medicine and Biology
  • "Gefitinib Inhibits Invasion and Metastasis of Osteosarcoma via Inhibition of Macrophage Receptor Interacting Serine-Threonine Kinase 2," 2020, published in Molecular Cancer Therapeutics
  • "Nanocell-mediated delivery of miR-34a counteracts temozolomide resistance in glioblastoma," 2021, published in Molecular Medicine
  • "Pharmacological prevention of surgery-accelerated metastasis in an animal model of osteosarcoma," 2020, published in Journal of Translational Medicine
  • "Childhood Brain Tumors: A Review of Strategies to Translate CNS Drug Delivery to Clinical Trials," 2023, published in Cancers

Their frequent co-authors in these endeavors include Caroline Maloney, Michelle P. Kallis, Samuel Z. Soffer, Bettie M. Steinberg, and Morris Edelman, each collaborating on multiple papers demonstrating ongoing research partnerships.

Marc Symons publishes regularly in various scientific venues. Frequent publication platforms include:

  • UNC Libraries
  • PEDIATRICS
  • Cancers
  • Advances in Experimental Medicine and Biology
  • Molecular Cancer Therapeutics

Best Publications

  • Activation of Raf as a result of recruitment to the plasma membrane

    David Stokoe;Susan G. Macdonald;Karen Cadwallader;Marc Symons

  • An essential role for Rac in Ras transformation

    Rong-Guo Qiu;Jing Chen;David Kirn;Frank McCormick

  • Wiskott–Aldrich Syndrome Protein, a Novel Effector for the GTPase CDC42Hs, Is Implicated in Actin Polymerization

    Marc Symons;Jonathan M.J Derry;Brian Karlak;Sharon Jiang

  • Molecular mechanisms of invadopodium formation the role of the N-WASP–Arp2/3 complex pathway and cofilin

    Hideki Yamaguchi;Mike Lorenz;Stephan Kempiak;Corina Sarmiento

  • Integrin-mediated Signals Regulated by Members of the Rho Family of GTPases

    Edwin A. Clark;Warren G. King;Joan S. Brugge;Marc Symons

  • A role for Rho in Ras transformation

    Rong-Guo Qiu;Jing Chen;Frank McCormick;Marc Symons

  • PDGF stimulates an increase in GTP–Rac via activation of phosphoinositide 3-kinase

    Phillip T. Hawkins;Alicia Eguinoa;Rong-Guo Qiu;David Stokoe

  • Binding of 14-3-3 proteins to the protein kinase Raf and effects on its activation

    Ellen Freed;Marc Symons;Susan G. Macdonald;Frank McCormick

  • Rac regulation of transformation, gene expression, and actin organization by multiple, PAK-independent pathways.

    J K Westwick;Q T Lambert;G J Clark;M Symons

  • Reactive oxygen species as essential mediators of cell adhesion: the oxidative inhibition of a FAK tyrosine phosphatase is required for cell adhesion.

    Paola Chiarugi;Giovambattista Pani;Elisa Giannoni;Letizia Taddei

  • Microglial stimulation of glioblastoma invasion involves epidermal growth factor receptor (EGFR) and colony stimulating factor 1 receptor (CSF-1R) signaling.

    Salvatore J Coniglio;Eliseo Eugenin;Kostantin Dobrenis;E Richard Stanley

  • Cdc42 regulates anchorage-independent growth and is necessary for Ras transformation.

    Rong-Guo Qiu;Arie Abo;Frank Mccormick;Marc Symons

  • Role of Rac1 and Oxygen Radicals in Collagenase-1 Expression Induced by Cell Shape Change

    Farrah Kheradmand;Erica Werner;Erica Werner;Patrice Tremble;Patrice Tremble;Marc Symons;Marc Symons

  • Control of actin polymerization in live and permeabilized fibroblasts.

    M H Symons;T J Mitchison

  • Rho family GTPases: the cytoskeleton and beyond

    Marc Symons

  • Cell migration and invasion assays.

    Aline Valster;Nhan L. Tran;Mitsutoshi Nakada;Michael E. Berens

  • Role of Rho family GTPases in epithelial morphogenesis

    Linda Van Aelst;Marc Symons

  • Activation of rat liver phospholipase D by the small GTP-binding protein RhoA.

    K. C. Malcolm;A. H. Ross;Rong-Guo Qiu;M. Symons

  • Roles of the Rac1 and Rac3 GTPases in human tumor cell invasion

    Amanda Y. Chan;Salvatore J. Coniglio;Ya Yu Chuang;David Michaelson

  • Rac mediates growth factor-induced arachidonic acid release

    Maikel P Peppelenbosch;Rong-Guo Qiu;Alicia M.M de Vries-Smits;Leon G.J Tertoolen

Frequent Co-Authors

Jann N. Sarkaria
Jann N. Sarkaria Mayo Clinic
Michael E. Berens
Michael E. Berens Translational Genomics Research Institute
Frank McCormick
Frank McCormick University of California, San Francisco
Jeffrey E. Segall
Jeffrey E. Segall Albert Einstein College of Medicine
Channing J. Der
Channing J. Der University of North Carolina at Chapel Hill
Raymond M. Schiffelers
Raymond M. Schiffelers Utrecht University
Han-Dong Sun
Han-Dong Sun Chinese Academy of Sciences
John S. Condeelis
John S. Condeelis Albert Einstein College of Medicine
James T. Rutka
James T. Rutka University of Toronto
Jonathan M. Backer
Jonathan M. Backer Albert Einstein College of Medicine

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