His primary areas of study are Cadherin, Cell biology, Catenin, Genetics and Cancer research. His work carried out in the field of Cadherin brings together such families of science as Transcription factor, Cell junction, Molecular biology, Cell adhesion and Tight junction. His study looks at the relationship between Transcription factor and fields such as Psychological repression, as well as how they intersect with chemical problems.
The Cell biology study combines topics in areas such as Desmoplakin, Desmosome assembly and Desmocollin. His Catenin study combines topics from a wide range of disciplines, such as Mutation, Beta-catenin, Carcinogenesis and Exon. His biological study spans a wide range of topics, including Loss of heterozygosity, CDH1, Tumor suppressor gene, Breast cancer and Adenomatous polyposis coli.
Frans van Roy spends much of his time researching Cell biology, Cadherin, Genetics, Catenin and Molecular biology. His studies deal with areas such as Cell culture, Embryonic stem cell, Cellular differentiation, Immunology and Plakophilins as well as Cell biology. Frans van Roy interconnects Cell adhesion, Phosphorylation and Pathology in the investigation of issues within Cadherin.
His Catenin research is multidisciplinary, incorporating elements of Beta-catenin, Cancer research and Cell adhesion molecule. The concepts of his Cancer research study are interwoven with issues in Carcinogenesis, Cancer, Tumor suppressor gene and Mutation. His study in Zinc finger extends to Molecular biology with its themes.
Frans van Roy mostly deals with Cell biology, Cadherin, Catenin, Cell junction and Adherens junction. His Cell biology study combines topics in areas such as Embryonic stem cell, Cell, Cell adhesion and Cellular differentiation. His primary area of study in Cadherin is in the field of Protocadherin.
Frans van Roy specializes in Catenin, namely Alpha catenin. His Cell junction study also includes
His scientific interests lie mostly in Cell biology, Genetics, Plakoglobin, Molecular evolution and Evolutionary biology. His Cell biology study focuses on Catenin in particular. He focuses mostly in the field of Plakoglobin, narrowing it down to topics relating to Protocadherin and, in certain cases, Armadillo and Protein family.
His research integrates issues of Most recent common ancestor, Phylogenetics, Armadillo repeats, BCL10 and Protein superfamily in his study of Evolutionary biology. He interconnects Lymnaea stagnalis, Xenopus, Cancer research and Wnt signaling pathway in the investigation of issues within Mutation. His work on CDH1 as part of general Cadherin study is frequently linked to Structure and function, therefore connecting diverse disciplines of science.
This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.
The Two-Handed E Box Binding Zinc Finger Protein SIP1 Downregulates E-Cadherin and Induces Invasion
Joke Comijn;Geert Berx;Petra Vermassen;Kristin Verschueren.
Molecular Cell (2001)
Phylogenetic analysis of the cadherin superfamily allows identification of six major subfamilies besides several solitary members.
Friedel Nollet;Patrick Kools;Frans van Roy.
Journal of Molecular Biology (2000)
The p300/CBP acetyltransferases function as transcriptional coactivators of β‐catenin in vertebrates
Andreas Hecht;Kris Vleminckx;Marc P. Stemmler;Frans van Roy.
The EMBO Journal (2000)
The Protein Kinase Akt Induces Epithelial Mesenchymal Transition and Promotes Enhanced Motility and Invasiveness of Squamous Cell Carcinoma Lines
Sylvia Julien Grille;Alfonso Bellacosa;John Upson;Andres J. Klein-Szanto.
Cancer Research (2003)
Mutations of the human E‐cadherin (CDH1) gene
Geert Berx;Karl-Friedrich Becker;Heinz Höfler;Frans van Roy.
Human Mutation (1998)
A novel role for p120 catenin in E-cadherin function.
Reneé C. Ireton;Michael A. Davis;Jolanda van Hengel;Deborah J. Mariner.
Journal of Cell Biology (2002)
SIP1/ZEB2 induces EMT by repressing genes of different epithelial cell–cell junctions
Cindy Vandewalle;Joke Comijn;Bram De Craene;Petra Vermassen.
Nucleic Acids Research (2005)
The E-cadherin/catenin complex: an important gatekeeper in breast cancer tumorigenesis and malignant progression.
Geert Berx;Frans Van Roy.
Breast Cancer Research (2001)
Molecular evolution of the cadherin superfamily
Paco Hulpiau;Frans van Roy.
The International Journal of Biochemistry & Cell Biology (2009)
α-Catenin-Vinculin Interaction Functions to Organize the Apical Junctional Complex in Epithelial Cells
Mitsuko Watabe-Uchida;Naoshige Uchida;Yuzo Imamura;Akira Nagafuchi.
Journal of Cell Biology (1998)
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