D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 45 Citations 11,185 87 World Ranking 12828 National Ranking 222

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • DNA
  • Genetics

His primary areas of study are Cadherin, Cell biology, Catenin, Genetics and Cancer research. His work carried out in the field of Cadherin brings together such families of science as Transcription factor, Cell junction, Molecular biology, Cell adhesion and Tight junction. His study looks at the relationship between Transcription factor and fields such as Psychological repression, as well as how they intersect with chemical problems.

The Cell biology study combines topics in areas such as Desmoplakin, Desmosome assembly and Desmocollin. His Catenin study combines topics from a wide range of disciplines, such as Mutation, Beta-catenin, Carcinogenesis and Exon. His biological study spans a wide range of topics, including Loss of heterozygosity, CDH1, Tumor suppressor gene, Breast cancer and Adenomatous polyposis coli.

His most cited work include:

  • The Two-Handed E Box Binding Zinc Finger Protein SIP1 Downregulates E-Cadherin and Induces Invasion (1126 citations)
  • Phylogenetic analysis of the cadherin superfamily allows identification of six major subfamilies besides several solitary members. (609 citations)
  • The p300/CBP acetyltransferases function as transcriptional coactivators of β‐catenin in vertebrates (521 citations)

What are the main themes of his work throughout his whole career to date?

Frans van Roy spends much of his time researching Cell biology, Cadherin, Genetics, Catenin and Molecular biology. His studies deal with areas such as Cell culture, Embryonic stem cell, Cellular differentiation, Immunology and Plakophilins as well as Cell biology. Frans van Roy interconnects Cell adhesion, Phosphorylation and Pathology in the investigation of issues within Cadherin.

His Catenin research is multidisciplinary, incorporating elements of Beta-catenin, Cancer research and Cell adhesion molecule. The concepts of his Cancer research study are interwoven with issues in Carcinogenesis, Cancer, Tumor suppressor gene and Mutation. His study in Zinc finger extends to Molecular biology with its themes.

He most often published in these fields:

  • Cell biology (40.97%)
  • Cadherin (39.58%)
  • Genetics (32.64%)

What were the highlights of his more recent work (between 2013-2020)?

  • Cell biology (40.97%)
  • Cadherin (39.58%)
  • Catenin (31.94%)

In recent papers he was focusing on the following fields of study:

Frans van Roy mostly deals with Cell biology, Cadherin, Catenin, Cell junction and Adherens junction. His Cell biology study combines topics in areas such as Embryonic stem cell, Cell, Cell adhesion and Cellular differentiation. His primary area of study in Cadherin is in the field of Protocadherin.

Frans van Roy specializes in Catenin, namely Alpha catenin. His Cell junction study also includes

  • Pathology and Fascia adherens most often made with reference to Cardiac muscle,
  • Intercalated disc, which have a strong connection to Biophysics. His biological study spans a wide range of topics, including Cerebral cortex, Neuroscience and Ependymal Cell.

Between 2013 and 2020, his most popular works were:

  • Beyond E-cadherin: roles of other cadherin superfamily members in cancer (229 citations)
  • Formin Is Associated with Left-Right Asymmetry in the Pond Snail and the Frog (105 citations)
  • Role of cell-cell adhesion complexes in embryonic stem cell biology. (90 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • DNA
  • Genetics

His scientific interests lie mostly in Cell biology, Genetics, Plakoglobin, Molecular evolution and Evolutionary biology. His Cell biology study focuses on Catenin in particular. He focuses mostly in the field of Plakoglobin, narrowing it down to topics relating to Protocadherin and, in certain cases, Armadillo and Protein family.

His research integrates issues of Most recent common ancestor, Phylogenetics, Armadillo repeats, BCL10 and Protein superfamily in his study of Evolutionary biology. He interconnects Lymnaea stagnalis, Xenopus, Cancer research and Wnt signaling pathway in the investigation of issues within Mutation. His work on CDH1 as part of general Cadherin study is frequently linked to Structure and function, therefore connecting diverse disciplines of science.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

The Two-Handed E Box Binding Zinc Finger Protein SIP1 Downregulates E-Cadherin and Induces Invasion

Joke Comijn;Geert Berx;Petra Vermassen;Kristin Verschueren.
Molecular Cell (2001)

1550 Citations

Phylogenetic analysis of the cadherin superfamily allows identification of six major subfamilies besides several solitary members.

Friedel Nollet;Patrick Kools;Frans van Roy.
Journal of Molecular Biology (2000)

950 Citations

The p300/CBP acetyltransferases function as transcriptional coactivators of β‐catenin in vertebrates

Andreas Hecht;Kris Vleminckx;Marc P. Stemmler;Frans van Roy.
The EMBO Journal (2000)

812 Citations

The Protein Kinase Akt Induces Epithelial Mesenchymal Transition and Promotes Enhanced Motility and Invasiveness of Squamous Cell Carcinoma Lines

Sylvia Julien Grille;Alfonso Bellacosa;John Upson;Andres J. Klein-Szanto.
Cancer Research (2003)

787 Citations

Mutations of the human E‐cadherin (CDH1) gene

Geert Berx;Karl-Friedrich Becker;Heinz Höfler;Frans van Roy.
Human Mutation (1998)

709 Citations

A novel role for p120 catenin in E-cadherin function.

Reneé C. Ireton;Michael A. Davis;Jolanda van Hengel;Deborah J. Mariner.
Journal of Cell Biology (2002)

645 Citations

SIP1/ZEB2 induces EMT by repressing genes of different epithelial cell–cell junctions

Cindy Vandewalle;Joke Comijn;Bram De Craene;Petra Vermassen.
Nucleic Acids Research (2005)

595 Citations

The E-cadherin/catenin complex: an important gatekeeper in breast cancer tumorigenesis and malignant progression.

Geert Berx;Frans Van Roy.
Breast Cancer Research (2001)

555 Citations

Molecular evolution of the cadherin superfamily

Paco Hulpiau;Frans van Roy.
The International Journal of Biochemistry & Cell Biology (2009)

468 Citations

α-Catenin-Vinculin Interaction Functions to Organize the Apical Junctional Complex in Epithelial Cells

Mitsuko Watabe-Uchida;Naoshige Uchida;Yuzo Imamura;Akira Nagafuchi.
Journal of Cell Biology (1998)

392 Citations

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