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Biology and Biochemistry

D-Index
83
Citations
39607
World Ranking
3425
National Ranking
55

Overview

Yvan Saeys is affiliated with Ghent University in Belgium and has contributed extensively to the field of Biochemistry, Genetics, and Molecular Biology, authoring a significant number of publications. Their research spans several subfields, including Molecular Biology, Immunology, Biophysics, Artificial Intelligence, and Plant Science.

Their scientific work focuses primarily on topics related to single-cell and spatial transcriptomics, cell image analysis techniques, immune cells in cancer, immune cell function and interaction, T-cell and B-cell immunology, immunotherapy and immune responses, as well as gene expression and cancer classification.

Saeys has published multiple papers in reputable journals. Notable recent papers include:

  • A scalable SCENIC workflow for single-cell gene regulatory network analysis, 2020, Nature Protocols
  • Spatial proteogenomics reveals distinct and evolutionarily conserved hepatic macrophage niches, 2022, Cell
  • Trajectory-based differential expression analysis for single-cell sequencing data, 2020, Nature Communications
  • A cell atlas of human thymic development defines T cell repertoire formation, 2020, Science
  • Single-cell profiling of myeloid cells in glioblastoma across species and disease stage reveals macrophage competition and specialization, 2021, Nature Neuroscience

Frequent coauthors in Saeys' research include Sofie Van Gassen, Ruth Seurinck, Niels Vandamme, Liesbet Martens, and Wouter Saelens, with collaboration counts ranging from 15 to 37 joint publications.

Their work has appeared repeatedly in venues such as bioRxiv (Cold Spring Harbor Laboratory), Cytometry Part A, arXiv (Cornell University), Nature Communications, and Zenodo (CERN European Organization for Nuclear Research).

Best Publications

  • A review of feature selection techniques in bioinformatics

    Yvan Saeys;Iñaki Inza;Pedro Larrañaga

  • FlowSOM: Using self-organizing maps for visualization and interpretation of cytometry data.

    Sofie Van Gassen;Sofie Van Gassen;Britt Callebaut;Mary J. Van Helden;Bart N. Lambrecht

  • A comparison of single-cell trajectory inference methods.

    Wouter Saelens;Robrecht Cannoodt;Robrecht Cannoodt;Helena Todorov;Helena Todorov;Yvan Saeys

  • NicheNet: modeling intercellular communication by linking ligands to target genes

    Robin Browaeys;Wouter Saelens;Yvan Saeys

  • A single-cell atlas of mouse brain macrophages reveals unique transcriptional identities shaped by ontogeny and tissue environment.

    Hannah Van Hove;Liesbet Martens;Isabelle Scheyltjens;Karen De Vlaminck

  • Genome analysis of the smallest free-living eukaryote Ostreococcus tauri unveils many unique features

    Evelyne Derelle;Conchita Ferraz;Stephane Rombauts;Pierre Rouzé

  • Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition)

    Andrea Cossarizza;Hyun Dong Chang;Andreas Radbruch;Andreas Acs

  • Bone marrow-derived monocytes give rise to self-renewing and fully differentiated Kupffer cells

    Charlotte L Scott;Fang Zheng;Fang Zheng;Patrick De Baetselier;Liesbet Martens

  • Unsupervised High-Dimensional Analysis Aligns Dendritic Cells across Tissues and Species.

    Martin Guilliams;Martin Guilliams;Charles-Antoine Dutertre;Charles-Antoine Dutertre;Charlotte L. Scott;Naomi McGovern

  • A scalable SCENIC workflow for single-cell gene regulatory network analysis.

    Bram Van de Sande;Christopher Flerin;Kristofer Davie;Maxime De Waegeneer

  • A cell atlas of human thymic development defines T cell repertoire formation.

    Jong-Eun Park;Rachel A. Botting;Cecilia Domínguez Conde;Dorin-Mirel Popescu

  • The function of Fcγ receptors in dendritic cells and macrophages

    Martin Guilliams;Pierre Bruhns;Yvan Saeys;Hamida Hammad

  • Robust biomarker identification for cancer diagnosis with ensemble feature selection methods

    Thomas Abeel;Thibault Helleputte;Yves Van de Peer;Pierre Dupont

  • Yolk Sac Macrophages, Fetal Liver, and Adult Monocytes Can Colonize an Empty Niche and Develop into Functional Tissue-Resident Macrophages

    Lianne van de Laar;Wouter Saelens;Sofie De Prijck;Liesbet Martens

  • Single-cell profiling of myeloid cells in glioblastoma across species and disease stage reveals macrophage competition and specialization.

    Ana Rita Pombo Antunes;Isabelle Scheyltjens;Francesca Lodi;Julie Messiaen

  • Stellate Cells, Hepatocytes, and Endothelial Cells Imprint the Kupffer Cell Identity on Monocytes Colonizing the Liver Macrophage Niche

    Johnny Bonnardel;Wouter T’Jonck;Djoere Gaublomme;Robin Browaeys

  • Trajectory-based differential expression analysis for single-cell sequencing data.

    Koen Van den Berge;Koen Van den Berge;Hector Roux de Bézieux;Kelly Street;Wouter Saelens

  • Computational flow cytometry: helping to make sense of high-dimensional immunology data

    Yvan Saeys;Sofie Van Gassen;Bart N. Lambrecht;Bart N. Lambrecht

  • Osteopontin Expression Identifies a Subset of Recruited Macrophages Distinct from Kupffer Cells in the Fatty Liver

    Anneleen Remmerie;Liesbet Martens;Tinne Thoné;Angela Castoldi

  • Robust biomarker identification for cancer diagnosis using ensemble feature selection methods

    Thomas Abeel;Thibault Helleputte;Yves Van de Peer;Pierre Dupont

Frequent Co-Authors

Yves Van de Peer
Yves Van de Peer Ghent University
Bart N. Lambrecht
Bart N. Lambrecht Ghent University
Tom Dhaene
Tom Dhaene Ghent University
Martin Guilliams
Martin Guilliams Ghent University
Wilfried Philips
Wilfried Philips Ghent University
Chris Cornelis
Chris Cornelis Ghent University
Pierre Rouzé
Pierre Rouzé Ghent University
Francisco Herrera
Francisco Herrera University of Granada
Hamida Hammad
Hamida Hammad Ghent University
Bernard De Baets
Bernard De Baets Ghent University

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