World's Best Scientists 2026 revealed!

D-Index & Metrics

Microbiology

D-Index
74
Citations
17070
World Ranking
1597
National Ranking
36

Manuel Fresno publication distribution in Microbiology in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Microbiology in 2026. The highlighted bar marks where Manuel Fresno sits on this spectrum.

55–64 publications: 8 scientists 65–74 publications: 29 scientists 75–84 publications: 55 scientists 85–94 publications: 112 scientists 95–104 publications: 137 scientists 105–114 publications: 190 scientists 115–124 publications: 235 scientists 125–134 publications: 234 scientists 135–144 publications: 288 scientists 145–154 publications: 264 scientists 155–164 publications: 264 scientists 165–174 publications: 253 scientists 175–184 publications: 276 scientists 185–194 publications: 190 scientists 195–204 publications: 233 scientists 205–214 publications: 207 scientists 215–224 publications: 198 scientists 225–234 publications: 155 scientists 235–244 publications: 161 scientists 245–254 publications: 160 scientists 255–264 publications: 146 scientists 265–274 publications: 139 scientists 275–284 publications: 148 scientists 285–294 publications: 115 scientists 295–304 publications: 96 scientists 305–314 publications: 88 scientists 315–324 publications: 106 scientists 325–334 publications: 65 scientists 335–344 publications: 76 scientists 345–354 publications: 64 scientists 355–364 publications: 62 scientists 365–374 publications: 65 scientists 375–384 publications: 61 scientists 385–394 publications: 34 scientists 395–404 publications: 44 scientists 405–414 publications: 36 scientists 415–424 publications: 35 scientists 425–434 publications: 29 scientists 435–444 publications: 33 scientists 445–454 publications: 34 scientists 455–464 publications: 25 scientists 465–474 publications: 26 scientists 475–484 publications: 20 scientists 485–494 publications: 19 scientists 495–504 publications: 16 scientists 505–514 publications: 17 scientists 515–524 publications: 23 scientists 525–534 publications: 14 scientists 535–544 publications: 14 scientists 545–554 publications: 18 scientists 555–564 publications: 12 scientists 565–574 publications: 7 scientists 575–584 publications: 9 scientists 585–594 publications: 9 scientists 595–604 publications: 9 scientists 605–614 publications: 7 scientists 615–624 publications: 9 scientists 625–634 publications: 7 scientists 635–644 publications: 4 scientists 645–654 publications: 5 scientists 655–664 publications: 6 scientists 665–674 publications: 7 scientists 675–678 publications: 3 scientists 679+ publications: 99 scientists
55 publications 679+

This scientist: 319 publications — 80th percentile

80% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 679 publications or more.

Manuel Fresno D-index placement in Microbiology in 2026

The chart shows the D-index (discipline H-index) distribution of Microbiology scientists ranked by Research.com in 2026. The highlighted bar marks where Manuel Fresno sits on this spectrum.

40 D-Index: 30 scientists 41 D-Index: 86 scientists 42 D-Index: 90 scientists 43 D-Index: 117 scientists 44 D-Index: 122 scientists 45 D-Index: 123 scientists 46 D-Index: 108 scientists 47 D-Index: 110 scientists 48 D-Index: 106 scientists 49 D-Index: 109 scientists 50 D-Index: 129 scientists 51 D-Index: 111 scientists 52 D-Index: 116 scientists 53 D-Index: 127 scientists 54 D-Index: 134 scientists 55 D-Index: 134 scientists 56 D-Index: 111 scientists 57 D-Index: 136 scientists 58 D-Index: 162 scientists 59 D-Index: 151 scientists 60 D-Index: 139 scientists 61 D-Index: 122 scientists 62 D-Index: 126 scientists 63 D-Index: 144 scientists 64 D-Index: 109 scientists 65 D-Index: 103 scientists 66 D-Index: 124 scientists 67 D-Index: 112 scientists 68 D-Index: 103 scientists 69 D-Index: 131 scientists 70 D-Index: 93 scientists 71 D-Index: 93 scientists 72 D-Index: 96 scientists 73 D-Index: 92 scientists 74 D-Index: 80 scientists 75 D-Index: 66 scientists 76 D-Index: 87 scientists 77 D-Index: 60 scientists 78 D-Index: 73 scientists 79 D-Index: 59 scientists 80 D-Index: 57 scientists 81 D-Index: 55 scientists 82 D-Index: 47 scientists 83 D-Index: 77 scientists 84 D-Index: 50 scientists 85 D-Index: 45 scientists 86 D-Index: 42 scientists 87 D-Index: 41 scientists 88 D-Index: 32 scientists 89 D-Index: 38 scientists 90 D-Index: 35 scientists 91 D-Index: 34 scientists 92 D-Index: 27 scientists 93 D-Index: 26 scientists 94 D-Index: 33 scientists 95 D-Index: 22 scientists 96 D-Index: 37 scientists 97 D-Index: 22 scientists 98 D-Index: 21 scientists 99 D-Index: 22 scientists 100 D-Index: 30 scientists 101 D-Index: 16 scientists 102 D-Index: 20 scientists 103 D-Index: 17 scientists 104 D-Index: 19 scientists 105 D-Index: 16 scientists 106 D-Index: 19 scientists 107 D-Index: 18 scientists 108 D-Index: 14 scientists 109 D-Index: 10 scientists 110 D-Index: 9 scientists 111 D-Index: 7 scientists 112 D-Index: 11 scientists 113 D-Index: 6 scientists 114 D-Index: 15 scientists 115 D-Index: 10 scientists 116 D-Index: 12 scientists 117 D-Index: 7 scientists 118 D-Index: 10 scientists 119 D-Index: 10 scientists 120 D-Index: 11 scientists 121 D-Index: 2 scientists 122 D-Index: 7 scientists 123 D-Index: 12 scientists 124 D-Index: 5 scientists 125 D-Index: 9 scientists 126 D-Index: 6 scientists 127+ D-Index: 95 scientists
40 D-Index 127+

This scientist: 74 D-Index — 72nd percentile

72% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 127 D-Index or more.

Overview

Manuel Fresno is affiliated with the Autonomous University of Madrid in Spain and focuses on research primarily within the fields of Medicine, Immunology and Microbiology, and Biochemistry, Genetics and Molecular Biology. Their work covers several subfields, including Immunology, Epidemiology, Infectious Diseases, Molecular Biology, and Public Health, Environmental and Occupational Health.

The main topics of Manuel Fresno's research activity include:

  • Trypanosoma species research and implications
  • Research on Leishmaniasis Studies
  • Immune Response and Inflammation
  • SARS-CoV-2 and COVID-19 Research
  • COVID-19 Clinical Research Studies
  • Immune cells in cancer
  • COVID-19 Impact on Reproduction

Frequent co-authors in Fresno's publications are:

  • Núria Gironès
  • Alfonso Herreros-Cabello
  • Francisco Callejas-Hernández
  • Konstantinos Stamatakis
  • María del Carmen Lapo Maza

Manuel Fresno has published extensively in several scientific venues, notably:

  • Frontiers in Immunology
  • Scientific Reports
  • bioRxiv (Cold Spring Harbor Laboratory)
  • International Journal of Molecular Sciences
  • Frontiers in Cellular and Infection Microbiology

Key recent papers authored include:

  • "Trypanosoma Cruzi Genome: Organization, Multi-Gene Families, Transcription, and Biological Implications" (2020), published in Genes
  • "Induction of TLR4/TLR2 Interaction and Heterodimer Formation by Low Endotoxic Atypical LPS" (2022), published in Frontiers in Immunology
  • "Is Covid-19 Severity Associated With ACE2 Degradation?" (2022), published in Frontiers in Drug Discovery
  • "Cyclooxygenase 2-Regulated Genes an Alternative Avenue to the Development of New Therapeutic Drugs for Colorectal Cancer" (2020), published in Frontiers in Pharmacology
  • "Flow cytometry multiplexed method for the detection of neutralizing human antibodies to the native SARS-CoV-2 spike protein" (2021), published in EMBO Molecular Medicine

Manuel Fresno's research addresses various aspects of immunology and infectious diseases, with notable attention to Trypanosoma species and related parasitic diseases, as well as COVID-19 and immune responses linked to viral infections and cancer.

Best Publications

  • Selective Inhibition of Vascular Endothelial Growth Factor–Mediated Angiogenesis by Cyclosporin a Roles of the Nuclear Factor of Activated T Cells and Cyclooxygenase 2

    Gabriela L. Hernández;Olga V. Volpert;Miguel A. Iñiguez;Elisa Lorenzo

  • The role of tumour necrosis factor, interleukin 6, interferon-γ and inducible nitric oxide synthase in the development and pathology of the nervous system

    Ma Angeles Muñoz-Fernández;Manuel Fresno

  • Synergism between tumor necrosis factor-alpha and interferon-gamma on macrophage activation for the killing of intracellular Trypanosoma cruzi through a nitric oxide-dependent mechanism.

    M A Muñoz-Fernández;M A Fernández;M Fresno

  • Inhibition of Translation in Eukaryotic Systems by Harringtonine

    Manuel Fresno;Antonio Jiménez;David Vázquez

  • An Essential Role of the Nuclear Factor of Activated T Cells in the Regulation of the Expression of the Cyclooxygenase-2 Gene in Human T Lymphocytes

    Miguel A. Íñiguez;Sara Martı́nez-Martı́nez;Carmen Punzón;Juan Miguel Redondo

  • Cyclooxygenase-2: a therapeutic target in angiogenesis

    Miguel A Iñiguez;Antonio Rodrı́guez;Olga V Volpert;Manuel Fresno

  • Prostaglandin E2 and T cells: friends or foes?

    Vinatha Sreeramkumar;Manuel Fresno;Natalia Cuesta

  • Induction of Cyclooxygenase-2 on Activated T Lymphocytes: Regulation of T Cell Activation by Cyclooxygenase-2 Inhibitors

    Miguel A. Iñiguez;Carmen Punzón;Manuel Fresno

  • Immunosuppression during acute Trypanosoma cruzi infection : involvement of Ly6G (Gr1^+)CD11b^+ immature myeloid suppressor cells

    Oscar Goñi;Pilar Alcaide;Manuel Fresno

  • Activation of human macrophages for the killing of intracellular Trypanosoma cruzi by TNF-α and IFN-γ through a nitric oxide-dependent mechanism

    Maria Angeles Muñoz-Fernández;Monica A. Fernández;Manuel Fresno

  • The hepatitis B virus X protein promotes tumor cell invasion by inducing membrane-type matrix metalloproteinase-1 and cyclooxygenase-2 expression

    Enrique Lara-Pezzi;Maria Victoria Gómez-Gaviro;Beatriz G. Gálvez;Emilia Mira

  • Nitric oxide-producing CD11b+Ly-6G(Gr-1)+CD31(ER-MP12)+cells in the spleen of cyclophosphamide–treated mice: implications for T-cell responses in immunosuppressed mice

    Iñigo Angulo;Iñigo Angulo;Federico Gómez de las Heras;Federico Gómez de las Heras;José F. Garcı́a-Bustos;José F. Garcı́a-Bustos;Domingo Gargallo;Domingo Gargallo

  • Cytokines in the Pathogenesis of and Protection against Malaria

    Iñigo Angulo;Manuel Fresno

  • T cell–intrinsic role of Nod2 in promoting type 1 immunity to Toxoplasma gondii

    Michael H. Shaw;Thornik Reimer;Carmen Sánchez-Valdepeñas;Neil Warner

  • Toll-like receptors, inflammation, metabolism and obesity.

    Manuel Fresno;Ruth Alvarez;Natalia Cuesta

  • Mitochondrial ROS Production Protects the Intestine from Inflammation through Functional M2 Macrophage Polarization.

    Laura Formentini;Laura Formentini;Fulvio Santacatterina;Fulvio Santacatterina;Cristina Núñez de Arenas;Cristina Núñez de Arenas;Konstantinos Stamatakis

  • Inhibition of Nuclear Factor κB Activation by a Virus-encoded IκB-like Protein

    Yolanda Revilla;Mario Callejo;Javier M. Rodrı́guez;Esther Culebras

  • Cytokines and infectious diseases

    Manuel Fresno;Manfred Kopf;Luis Rivas

  • IFN-gamma-induced TNF-alpha expression is regulated by interferon regulatory factors 1 and 8 in mouse macrophages.

    Virginia Vila-del Sol;Carmen Punzón;Manuel Fresno

  • Carcinoma-associated fibroblasts derive from mesothelial cells via mesothelial-to-mesenchymal transition in peritoneal metastasis

    Pilar Sandoval;Jose Antonio Jiménez-Heffernan;Ángela Rynne-Vidal;María Luisa Pérez-Lozano

  • Prostanoid signal transduction and gene expression in the endothelium: Role in cardiovascular diseases

    Arántzazu Alfranca;Arántzazu Alfranca;Miguel A. Iñiguez;Manuel Fresno;Juan Miguel Redondo;Juan Miguel Redondo

  • Phosphodiesterase 4 inhibitors prevent cytokine secretion by T lymphocytes by inhibiting nuclear factor-kappaB and nuclear factor of activated T cells activation.

    J L Jimenez;C Punzón;J Navarro;M A Muñoz-Fernández

Frequent Co-Authors

Francisco Sánchez-Madrid
Francisco Sánchez-Madrid Autonomous University of Madrid
Balbino Alarcón
Balbino Alarcón Spanish National Research Council
Juan Miguel Redondo
Juan Miguel Redondo Spanish National Centre for Cardiovascular Research
David Vazquez
David Vazquez Autonomous University of Madrid
Miguel A. Alonso
Miguel A. Alonso Spanish National Research Council
Luis Carrasco
Luis Carrasco Centro de Biología Molecular Severo Ochoa
Manuel López-Cabrera
Manuel López-Cabrera Spanish National Research Council
Gema Moreno-Bueno
Gema Moreno-Bueno The University of Texas MD Anderson Cancer Center
Manuel Soto
Manuel Soto Autonomous University of Madrid
Santiago Mas-Coma
Santiago Mas-Coma University of Valencia

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