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Biology and Biochemistry

D-Index
52
Citations
7573
World Ranking
16870
National Ranking
6952

Overview

David M. Engman is affiliated with Northwestern University in the United States and primarily works within the field of Medicine. Their research spans several subfields, including Epidemiology, Public Health, Environmental and Occupational Health, Organic Chemistry, Infectious Diseases, and Molecular Biology.

The core topics of Engman's work focus extensively on Trypanosoma species research and implications and Research on Leishmaniasis Studies. Additional areas of study include Synthesis and Biological Evaluation, as well as investigations into COVID-19, covering COVID-19 Clinical Research Studies, SARS-CoV-2 and COVID-19 Research, and the COVID-19 Impact on Reproduction. Parasite-host interactions also form a part of their scientific exploration.

Key papers authored or co-authored by Engman reflect these themes across several respected venues. Notable recent publications include:

  • "Precision Health for Chagas Disease: Integrating Parasite and Host Factors to Predict Outcome of Infection and Response to Therapy" (2020) in Frontiers in Cellular and Infection Microbiology
  • "TMPRSS2 activity may mediate sex differences in COVID-19 severity" (2021) in Signal Transduction and Targeted Therapy
  • "Leishmaniasis and Chagas disease: Is there hope in nanotechnology to fight neglected tropical diseases?" (2022) in Frontiers in Cellular and Infection Microbiology
  • "Comparison of Large, Medium, and Small Solid Tumor Gene Panels for Detection of Clinically Actionable Mutations in Cancer" (2020) in Targeted Oncology
  • "Repurposing Carvedilol as a Novel Inhibitor of the Trypanosoma cruzi Autophagy Flux That Affects Parasite Replication and Survival" (2021) in Frontiers in Cellular and Infection Microbiology

Engman frequently publishes in Frontiers in Cellular and Infection Microbiology, which accounts for multiple articles in their portfolio. Other publication venues include Signal Transduction and Targeted Therapy, Targeted Oncology, JCI Insight, and Biomaterials.

Among frequent collaborators are Débora B. Scariot, Xiaomo Li, Evan A. Scott, Santiago Martínez, and Patricia Silvia Romano, with counts of multiple co-authored works indicating ongoing research partnerships.

Best Publications

  • The Life cycle of Trypanosoma cruzi revisited

    K.M. Tyler;D.M. Engman

  • Enhanced Efferocytosis of Apoptotic Cardiomyocytes Through Myeloid-Epithelial-Reproductive Tyrosine Kinase Links Acute Inflammation Resolution to Cardiac Repair After Infarction

    Elaine Wan;Xin-Yi Yeap;Shirley Dehn;Rachael L. Terry

  • Are MD-PhD programs meeting their goals? An analysis of career choices made by graduates of 24 MD-PhD programs.

    Lawrence F. Brass;Myles H. Akabas;Linda D. Burnley;David M. Engman

  • Chagas heart disease pathogenesis: one mechanism or many?

    Kevin M Bonney;David M Engman

  • Pathology and Pathogenesis of Chagas Heart Disease

    Kevin M. Bonney;Daniel J. Luthringer;Stacey A. Kim;Nisha J. Garg

  • The 35-nucleotide spliced leader sequence is common to all trypanosome messenger RNA's

    Joseph A. Walder;Paul S. Eder;David M. Engman;Steven T. Brentano

  • Induction of cardiac autoimmunity in Chagas heart disease: A case for molecular mimicry

    Edecio Cunha-Neto;Angelina M Bilate;Kenneth V Hyland;Simone G Fonseca

  • Flagellar protein localization mediated by a calcium–myristoyl/palmitoyl switch mechanism

    Lisa M. Godsel;David M. Engman

  • Extracellular Release of the Glycosylphosphatidylinositol (GPI)-linked Leishmania Surface Metalloprotease, gp63, Is Independent of GPI Phospholipolysis IMPLICATIONS FOR PARASITE VIRULENCE

    Bradford S. McGwire;Bradford S. McGwire;William A. O'Connell;Kwang-Poo Chang;David M. Engman

  • Migration through the Extracellular Matrix by the Parasitic Protozoan Leishmania Is Enhanced by Surface Metalloprotease gp63

    Bradford S. McGwire;Bradford S. McGwire;Kwang-Poo Chang;David M. Engman

  • Pathogenesis of Chagas heart disease: role of autoimmunity

    David M. Engman;Juan S. Leon

  • Flagellar membrane localization via association with lipid rafts

    Kevin M. Tyler;Alina Fridberg;Krista M. Toriello;Cheryl L. Olson

  • Killing of African Trypanosomes by Antimicrobial Peptides

    Bradford S. McGwire;Cheryl L. Olson;Brian F. Tack;David M. Engman

  • Molecular mechanisms of protein and lipid targeting to ciliary membranes

    Brian T. Emmer;Danijela Maric;David M. Engman

  • The major surface-metalloprotease of the parasitic protozoan, Leishmania, protects against antimicrobial peptide-induced apoptotic killing.

    Manjusha M. Kulkarni;W. Robert McMaster;Elzbieta Kamysz;Wojciech Kamysz

  • A novel flagellar Ca2+-binding protein in trypanosomes.

    D M Engman;K H Krause;K H Krause;J H Blumin;K S Kim

  • Molecular Mechanisms of Host Cell Invasion by Trypanosoma cruzi

    Conrad L. Epting;Bria M. Coates;David M. Engman

  • Cardiac antigen-specific autoantibody production is associated with cardiomyopathy in Trypanosoma cruzi-infected mice.

    Randal S. Tibbetts;Thomas S. McCormick;Edwin C. Rowland;Stephen D. Miller

  • Autoimmune Pathogenesis of Chagas Heart Disease: Looking Back, Looking Ahead

    Kevin M. Bonney;David M. Engman

  • Molecular cloning of mtp70, a mitochondrial member of the hsp70 family.

    D M Engman;L V Kirchhoff;J E Donelson

Frequent Co-Authors

John E. Donelson
John E. Donelson University of Iowa
Stephen D. Miller
Stephen D. Miller Northwestern University
Igor C. Almeida
Igor C. Almeida The University of Texas at El Paso
Kari C. Nadeau
Kari C. Nadeau Harvard University
Roberto Docampo
Roberto Docampo University of Georgia
Silvia N. J. Moreno
Silvia N. J. Moreno University of Georgia
Ernesto S. Nakayasu
Ernesto S. Nakayasu Pacific Northwest National Laboratory
Antoniana U. Krettli
Antoniana U. Krettli Oswaldo Cruz Foundation
Renato A. Mortara
Renato A. Mortara Federal University of Sao Paulo
Liléia Diotaiuti
Liléia Diotaiuti Oswaldo Cruz Foundation

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