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D-Index & Metrics

Biology and Biochemistry

D-Index
53
Citations
9937
World Ranking
16184
National Ranking
6707

Robert A. Nicholas publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where Robert A. Nicholas sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 414 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 849 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 950 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 841 scientists 207–216 publications: 735 scientists 217–226 publications: 709 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 418 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 197 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 60 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 134 publications — 19th percentile

19% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

Robert A. Nicholas D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Robert A. Nicholas sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 317 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 900 scientists 52–53 D-Index: 1,026 scientists 54–55 D-Index: 1,150 scientists 56–57 D-Index: 1,236 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,163 scientists 62–63 D-Index: 1,131 scientists 64–65 D-Index: 1,032 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 715 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 72 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 53 D-Index — 19th percentile

19% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Overview

Robert A. Nicholas is affiliated with the University of North Carolina at Chapel Hill in the United States. Their research primarily spans the fields of Medicine; Biochemistry, Genetics and Molecular Biology; and Immunology and Microbiology. Within these broader areas, they focus on subfields such as Microbiology, Physiology, Molecular Biology, Molecular Medicine, and Oncology.

The scientist's work covers a range of main topics, including:

  • Bacterial Infections and Vaccines
  • Reproductive tract infections research
  • Adenosine and Purinergic Signaling
  • Receptor Mechanisms and Signaling
  • Antibiotic Resistance in Bacteria
  • Gastroesophageal reflux and treatments
  • Pneumonia and Respiratory Infections

Robert A. Nicholas has contributed to numerous publications with a notable presence in several venues. The most frequent publication outlets include UNC Libraries, bioRxiv (Cold Spring Harbor Laboratory), Journal of Biological Chemistry, PLoS ONE, and ACS Infectious Diseases.

Selected recent papers include:

  • "Preclinical safety and efficacy characterization of an LpxC inhibitor against Gram-negative pathogens" (2023), Science Translational Medicine
  • "Mutations in penicillin-binding protein 2 from cephalosporin-resistant Neisseria gonorrhoeae hinder ceftriaxone acylation by restricting protein dynamics" (2020), Journal of Biological Chemistry
  • "High-Level Cefixime- and Ceftriaxone-Resistant Neisseria gonorrhoeae in France: Novel penA Mosaic Allele in a Successful International Clone Causes Treatment Failure" (2020), UNC Libraries
  • "Mutations in PBP2 from ceftriaxone-resistant Neisseria gonorrhoeae alter the dynamics of the β3-β4 loop to favor a low-affinity drug-binding state" (2021), Journal of Biological Chemistry
  • "Commensal Neisseria species share immune suppressive mechanisms with Neisseria gonorrhoeae" (2023), PLoS ONE

The scientist has frequently collaborated with several researchers, including:

  • Christopher Davies
  • Joshua Tomberg
  • T. Kendall Harden
  • Alena Fedarovich
  • Ann E. Jerse

Best Publications

  • High-level cefixime- and ceftriaxone-resistant Neisseria gonorrhoeae in France: novel penA mosaic allele in a successful international clone causes treatment failure.

    Magnus Unemo;Daniel Golparian;Robert Nicholas;Makoto Ohnishi

  • Emergence of multidrug-resistant, extensively drug-resistant and untreatable gonorrhea

    Magnus Unemo;Robert A Nicholas

  • Uridine nucleotide selectivity of three phospholipase C-activating P2 receptors: identification of a UDP-selective, a UTP-selective, and an ATP- and UTP-specific receptor.

    Robert A. Nicholas;William C. Watt;Eduardo R. Lazarowski;Qing Li

  • P2-Purinergic Receptors: Subtype-Associated Signaling Responses and Structure

    T K Harden;J L Boyer;R A Nicholas

  • Second messenger cascade specificity and pharmacological selectivity of the human P2Y1-purinoceptor

    Joel B. Schachter;Qing Li;José L. Boyer;Robert A. Nicholas

  • Physiological regulation of ATP release at the apical surface of human airway epithelia.

    Seiko F. Okada;Robert A. Nicholas;Silvia M. Kreda;Eduardo R. Lazarowski

  • Neisseria gonorrhoeae isolates with reduced susceptibility to cefixime and ceftriaxone: association with genetic polymorphisms in penA, mtrR, porB1b, and ponA.

    Robert Lindberg;Hans Fredlund;Robert Nicholas;Magnus Unemo

  • Expression of a cloned P2Y purinergic receptor that couples to phospholipase C.

    T M Filtz;Q Li;J L Boyer;R A Nicholas

  • Agonist Action of Adenosine Triphosphates at the Human P2Y1 Receptor

    R. Kyle Palmer;José L. Boyer;Joel B. Schachter;Robert A. Nicholas

  • Mutations in ponA, the Gene Encoding Penicillin-Binding Protein 1, and a Novel Locus, penC, Are Required for High-Level Chromosomally Mediated Penicillin Resistance in Neisseria gonorrhoeae

    Patricia A. Ropp;Mei Hu;Melanie Olesky;Robert A. Nicholas

  • Overexpression of the MtrC-MtrD-MtrE Efflux Pump Due to an mtrR Mutation Is Required for Chromosomally Mediated Penicillin Resistance in Neisseria gonorrhoeae

    Wendy L. Veal;Wendy L. Veal;Robert A. Nicholas;William M. Shafer;William M. Shafer

  • Voltage-dependent Anion Channel-1 (VDAC-1) Contributes to ATP Release and Cell Volume Regulation in Murine Cells

    Seiko F. Okada;Wanda K. O'Neal;Pingbo Huang;Robert A. Nicholas

  • Genetics of chromosomally mediated intermediate resistance to ceftriaxone and cefixime in Neisseria gonorrhoeae.

    Shuqing Zhao;Margaret Duncan;Joshua Tomberg;Christopher Davies

  • Identification and Analysis of Amino Acid Mutations in Porin IB That Mediate Intermediate-Level Resistance to Penicillin and Tetracycline in Neisseria gonorrhoeae

    Melanie Olesky;Marcia Hobbs;Robert A. Nicholas

  • HEK293 human embryonic kidney cells endogenously express the P2Y1 and P2Y2 receptors.

    Joel B. Schachter;Susan M. Sromek;Robert A. Nicholas;T.Kendall Harden

  • Porin-Mediated Antibiotic Resistance in Neisseria gonorrhoeae: Ion, Solute, and Antibiotic Permeation through PIB Proteins with penB Mutations

    Melanie Olesky;Shuqing Zhao;Robert L. Rosenberg;Robert A. Nicholas

  • The Role of Amino Acids in Extracellular Loops of the Human P2Y1 Receptor in Surface Expression and Activation Processes

    Carsten Hoffmann;Stefano Moro;Robert A. Nicholas;T. Kendall Harden

  • Extracellular NAD+ is an agonist of the human P2Y11 purinergic receptor in human granulocytes.

    Iliana Moreschi;Santina Bruzzone;Robert A. Nicholas;Floriana Fruscione

  • Molecular and structural analysis of mosaic variants of penicillin-binding protein 2 conferring decreased susceptibility to expanded-spectrum cephalosporins in Neisseria gonorrhoeae: Role of epistatic mutations

    Joshua Tomberg;Magnus Unemo;Christopher Davies;Robert A Nicholas

  • ATP, an agonist at the rat P2Y(4) receptor, is an antagonist at the human P2Y(4) receptor.

    C Kennedy;A D Qi;C L Herold;T K Harden

Frequent Co-Authors

T. Kendall Harden
T. Kendall Harden University of North Carolina at Chapel Hill
Magnus Unemo
Magnus Unemo Örebro University
Eduardo R. Lazarowski
Eduardo R. Lazarowski University of North Carolina at Chapel Hill
José L. Boyer
José L. Boyer Inspire Pharmaceuticals
William M. Shafer
William M. Shafer Emory University
Ann E. Jerse
Ann E. Jerse Uniformed Services University of the Health Sciences
Kenneth A. Jacobson
Kenneth A. Jacobson National Institutes of Health
Makoto Ohnishi
Makoto Ohnishi National Institutes of Health
Wanda K. O'Neal
Wanda K. O'Neal University of North Carolina at Chapel Hill
Charles Kennedy
Charles Kennedy University of Strathclyde

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