His primary areas of study are Immunology, Immune system, Haematopoiesis, Antigen and Antibody. His Immunology research is multidisciplinary, incorporating perspectives in Induced pluripotent stem cell, Xenotransplantation, Severe combined immunodeficiency and Cell biology. His studies in Immune system integrate themes in fields like Molecular biology, Cell therapy, Transplantation and Tyrosine phosphorylation.
His Haematopoiesis research includes themes of Nod and Adult stem cell. As a part of the same scientific study, he usually deals with the Antigen, concentrating on Humanized mouse and frequently concerns with Viral pathogenesis, Lymphocyte function-associated antigen 1 and Gene knockdown. His work carried out in the field of Antibody brings together such families of science as Progenitor cell and T cell.
Yong-Guang Yang focuses on Immunology, Immune system, Transplantation, Haematopoiesis and Bone marrow. His work deals with themes such as Hematopoietic stem cell transplantation, Stem cell and Xenotransplantation, which intersect with Immunology. His Immune system study combines topics in areas such as Cancer research, Cell therapy and Antigen.
His Transplantation research also works with subjects such as
His scientific interests lie mostly in Cancer research, Immune system, Chemistry, T cell and Humanized mouse. In his study, Metastasis is inextricably linked to CD8, which falls within the broad field of Cancer research. His research on Immune system concerns the broader Immunology.
His Immunology study combines topics from a wide range of disciplines, such as Anemia, Coagulopathy and Transplantation. His research investigates the connection between T cell and topics such as Macrophage that intersect with problems in CD47 and Red blood cell. His Humanized mouse study integrates concerns from other disciplines, such as Cancer, Haematopoiesis, Progenitor cell, Human tumor and Long term survival.
His main research concerns T cell, Antigen, Cancer research, CD8 and Cytotoxic T cell. T cell is the subject of his research, which falls under Immunology. His research on Antigen often connects related topics like T-cell receptor.
The Cancer research study combines topics in areas such as Immune system and Immunotherapy. His Immune system study frequently draws connections to other fields, such as Leukemia. The concepts of his Cytotoxic T cell study are interwoven with issues in Epitope, Clonal deletion, Thymocyte and Cell biology.
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Hematopoietic stem cell quiescence maintained by p21cip1/waf1.
Tao Cheng;Neil Rodrigues;Hongmei Shen;Yong-guang Yang.
Science (2000)
T Cell-Specific siRNA Delivery Suppresses HIV-1 Infection in Humanized Mice
Priti Kumar;Hong Seok Ban;Sang Soo Kim;Haoquan Wu.
Cell (2008)
Reconstitution of a functional human immune system in immunodeficient mice through combined human fetal thymus/liver and CD34+ cell transplantation.
Ping Lan;Noriko Tonomura;Akira Shimizu;Shumei Wang.
Blood (2006)
Efficient generation of lung and airway epithelial cells from human pluripotent stem cells
Sarah X L Huang;Mohammad Naimul Islam;John O'Neill;Zheng Hu.
Nature Biotechnology (2014)
Xenotransplantation: current status and a perspective on the future.
Yong-Guang Yang;Megan Sykes.
Nature Reviews Immunology (2007)
Induction of Robust Cellular and Humoral Virus-Specific Adaptive Immune Responses in Human Immunodeficiency Virus-Infected Humanized BLT Mice
Diana M. Brainard;Edward Seung;Nicole Frahm;Nicole Frahm;Annaiah Cariappa.
Journal of Virology (2009)
Role for CD47-SIRPα signaling in xenograft rejection by macrophages
Kentaro Ide;Hui Wang;Hiroyuki Tahara;Jianxiang Liu.
Proceedings of the National Academy of Sciences of the United States of America (2007)
Tolerization of Anti–Galα1-3Gal Natural Antibody–forming B Cells by Induction of Mixed Chimerism
Yong-Guang Yang;Emil deGoma;Hideki Ohdan;Jennifer L. Bracy.
Journal of Experimental Medicine (1998)
Donor-derived interferon gamma is required for inhibition of acute graft-versus-host disease by interleukin 12.
Yong-Guang Yang;Bimalangshu R. Dey;Justin J. Sergio;Denise A. Pearson.
Journal of Clinical Investigation (1998)
Lymphohematopoietic graft-vs.-host reactions can be induced without graft-vs.-host disease in murine mixed chimeras established with a cyclophosphamide-based nonmyeloablative conditioning regimen
Michele R Pelot;Denise A Pearson;Kirsten Swenson;Guiling Zhao.
Biology of Blood and Marrow Transplantation (1999)
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