D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 52 Citations 17,707 82 World Ranking 9072 National Ranking 315

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Immune system
  • Antibody

His primary areas of investigation include CD40, Molecular biology, Immunology, Cytokine and T cell. His CD40 research is multidisciplinary, relying on both Immunoglobulin class switching, Secretion, Antigen and Antibody, Monoclonal antibody. William C. Fanslow interconnects Chemokine, ULBP1 and Cell biology in the investigation of issues within Antigen.

He combines subjects such as Receptor, Interleukin-21 receptor, Interleukin-17 receptor and CD30 with his study of Molecular biology. His research in Immunology is mostly concerned with Immune system. His studies deal with areas such as Complementary DNA and Peptide sequence as well as T cell.

His most cited work include:

  • ULBPs, Novel MHC Class I–Related Molecules, Bind to CMV Glycoprotein UL16 and Stimulate NK Cytotoxicity through the NKG2D Receptor (1125 citations)
  • Molecular and biological characterization of a murine ligand for CD40 (1022 citations)
  • Human IL-17: a novel cytokine derived from T cells. (942 citations)

What are the main themes of his work throughout his whole career to date?

His scientific interests lie mostly in CD40, Molecular biology, Antibody, Immunology and Biochemistry. His CD40 study combines topics from a wide range of disciplines, such as Cell culture, Cancer research, Antigen, B cell and Monoclonal antibody. His work carried out in the field of Molecular biology brings together such families of science as T cell, Interleukin 21, Receptor, Peptide sequence and Interleukin-4 receptor.

William C. Fanslow studied T cell and Cytotoxic T cell that intersect with Cell biology and CD8. His Antibody research is multidisciplinary, incorporating perspectives in Mutation, Polynucleotide and Virology. In his research, In vitro and Stimulation is intimately related to In vivo, which falls under the overarching field of Immunology.

He most often published in these fields:

  • CD40 (35.45%)
  • Molecular biology (35.45%)
  • Antibody (26.36%)

What were the highlights of his more recent work (between 2004-2019)?

  • Antibody (26.36%)
  • Angiogenesis (10.91%)
  • Biochemistry (19.09%)

In recent papers he was focusing on the following fields of study:

William C. Fanslow mainly investigates Antibody, Angiogenesis, Biochemistry, Immunology and Molecular biology. The concepts of his Antibody study are interwoven with issues in Receptor, Cell, Polynucleotide and Pharmacology. His Immunology research incorporates elements of Interleukin-21 receptor and Cell biology.

William C. Fanslow studied Cell biology and Antigen that intersect with Immunotherapy, Hyper IgM syndrome, Interferon gamma, CD40 and Immune system. The various areas that William C. Fanslow examines in his Molecular biology study include Pharmacokinetics, In vitro, Immunoglobulin G, Recombinant CD40-Ligand and X-Linked Hyper IgM Syndrome. His Epitope study incorporates themes from Nectin, Cytotoxic T cell, T cell, Antigen-presenting cell and Function.

Between 2004 and 2019, his most popular works were:

  • Nectin-like protein 2 defines a subset of T-cell zone dendritic cells and is a ligand for class-I-restricted T-cell-associated molecule. (170 citations)
  • A Novel Antibody Engineering Strategy for Making Monovalent Bispecific Heterodimeric IgG Antibodies by Electrostatic Steering Mechanism (66 citations)
  • Asymmetrical Fc Engineering Greatly Enhances Antibody-dependent Cellular Cytotoxicity (ADCC) Effector Function and Stability of the Modified Antibodies (57 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Immune system
  • Antibody

The scientist’s investigation covers issues in Antibody, Antigen, Cell culture, Immunology and Cell. His studies in Antibody integrate themes in fields like Molecular biology and Receptor. The Molecular biology study combines topics in areas such as Immunoglobulin G, Immunoglobulin Fc Fragments, Antibody-dependent cell-mediated cytotoxicity, Fragment crystallizable region and Effector.

Nectin is closely connected to Cell biology in his research, which is encompassed under the umbrella topic of Antigen. His work on Immunology is being expanded to include thematically relevant topics such as CD40. William C. Fanslow has researched Cell in several fields, including Cell-mediated cytotoxicity, Mouse xenograft, Tumor growth, Transfection and Pharmacology.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

ULBPs, Novel MHC Class I–Related Molecules, Bind to CMV Glycoprotein UL16 and Stimulate NK Cytotoxicity through the NKG2D Receptor

David Cosman;Jürgen Müllberg;Claire L. Sutherland;Wilson Chin.
Immunity (2001)

1813 Citations

Human IL-17: a novel cytokine derived from T cells.

Zhengbin Yao;S. L. Painter;W. C. Fanslow;D. Ulrich.
Journal of Immunology (1995)

1485 Citations

Herpesvirus saimiri encodes a new cytokine, IL-17, which binds to a novel cytokine receptor.

Zhengbin Yao;William C. Fanslow;Michael F. Seldin;Anne Marie Rousseau.
Immunity (1995)

1409 Citations

Molecular and biological characterization of a murine ligand for CD40

Richard J. Armitage;William C. Fanslow;Laura Strockbine;Timothy A. Sato.
Nature (1992)

1276 Citations

CD40 ligand gene defects responsible for X-linked hyper-IgM syndrome

R. Cutler Allen;Richard J. Armitage;Mary Ellen Conley;Howard Rosenblatt.
Science (1993)

1151 Citations

CD30 antigen, a marker for Hodgkin's lymphoma, is a receptor whose ligand defines an emerging family of cytokines with homology to TNF

Craig A. Smith;Hans Juergen Gruss;Terri Davis;Dirk Anderson.
Cell (1993)

801 Citations

A Novel TNF Receptor Family Member Binds TWEAK and Is Implicated in Angiogenesis

Steven R Wiley;Linda Cassiano;Timothy Lofton;Terry Davis-Smith.
Immunity (2001)

508 Citations

Evidence for a Role of IL-17 in Organ Allograft Rejection: IL-17 Promotes the Functional Differentiation of Dendritic Cell Progenitors

Mary A. Antonysamy;William C. Fanslow;Fumin Fu;Wei Li.
Journal of Immunology (1999)

478 Citations

Molecular cloning of a ligand for the inducible T cell gene 4-1BB: a member of an emerging family of cytokines with homology to tumor necrosis factor.

Raymond G. Goodwin;Wenie S. Din;Terri Davis-Smith;Dirk M. Anderson.
European Journal of Immunology (1993)

477 Citations

CD40 Ligand Is Required for Protective Cell-Mediated Immunity to Leishmania major

Kim A Campbell;Pamela J Ovendale;Mary K Kennedy;William C Fanslow.
Immunity (1996)

469 Citations

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