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William C. Fanslow

William C. Fanslow

D-Index & Metrics

Biology and Biochemistry

D-Index
68
Citations
23449
World Ranking
7653
National Ranking
265

Overview

William C. Fanslow is affiliated with Fibrocor Therapeutics in Canada. Their research primarily spans the field of Medicine, with specific contributions to Radiology, Nuclear Medicine and Imaging, Genetics, and Pathology and Forensic Medicine.

Their work covers several main topics including:

  • Monoclonal and Polyclonal Antibodies Research
  • Chronic Lymphocytic Leukemia Research
  • Lymphoma Diagnosis and Treatment

Fanslow has authored publications in prominent venues such as Cancer Research, where they contributed a paper titled Abstract 2902: Development of PSB202, a bifunctional antibody pair that target CD20 and CD37, for the treatment of B-cell malignancies published in 2022.

Frequent coauthors collaborating with Fanslow include:

  • Paul A. Algate
  • Zhi Liu
  • Saying Yuan
  • Hua Liu
  • Cristina Domeier

The scientific output reflects a focus on immunological therapies related to hematologic malignancies, especially B-cell lymphomas and leukemia. The 2022 publication introduces PSB202, a bifunctional antibody treatment designed to simultaneously target CD20 and CD37 molecules, which play roles in B-cell malignancies.

By integrating expertise across multiple subfields of Medicine, Fanslow's contributions connect advances in antibody research with clinical applications in chronic lymphocytic leukemia and lymphoma diagnosis and treatment strategies.

Best Publications

  • ULBPs, Novel MHC Class I–Related Molecules, Bind to CMV Glycoprotein UL16 and Stimulate NK Cytotoxicity through the NKG2D Receptor

    David Cosman;Jürgen Müllberg;Claire L. Sutherland;Wilson Chin

  • Human IL-17: a novel cytokine derived from T cells.

    Zhengbin Yao;S. L. Painter;W. C. Fanslow;D. Ulrich

  • Herpesvirus saimiri encodes a new cytokine, IL-17, which binds to a novel cytokine receptor.

    Zhengbin Yao;William C. Fanslow;Michael F. Seldin;Anne Marie Rousseau

  • Molecular and biological characterization of a murine ligand for CD40

    Richard J. Armitage;William C. Fanslow;Laura Strockbine;Timothy A. Sato

  • CD40 ligand gene defects responsible for X-linked hyper-IgM syndrome

    R. Cutler Allen;Richard J. Armitage;Mary Ellen Conley;Howard Rosenblatt

  • CD40 expression by human monocytes: regulation by cytokines and activation of monocytes by the ligand for CD40.

    M R Alderson;R J Armitage;T W Tough;L Strockbine

  • CD30 antigen, a marker for Hodgkin's lymphoma, is a receptor whose ligand defines an emerging family of cytokines with homology to TNF

    Craig A. Smith;Hans Juergen Gruss;Terri Davis;Dirk Anderson

  • CD40 on human endothelial cells: inducibility by cytokines and functional regulation of adhesion molecule expression.

    Karin Karmann;Christopher C. W. Hughes;Jeffrey Schechner;William C. Fanslow

  • Recombinant human CD40 ligand stimulates B cell proliferation and immunoglobulin E secretion.

    M K Spriggs;R J Armitage;L Strockbine;K N Clifford

  • A Novel TNF Receptor Family Member Binds TWEAK and Is Implicated in Angiogenesis

    Steven R Wiley;Linda Cassiano;Timothy Lofton;Terry Davis-Smith

  • Molecular cloning of a ligand for the inducible T cell gene 4-1BB: a member of an emerging family of cytokines with homology to tumor necrosis factor.

    Raymond G. Goodwin;Wenie S. Din;Terri Davis-Smith;Dirk M. Anderson

  • Evidence for a Role of IL-17 in Organ Allograft Rejection: IL-17 Promotes the Functional Differentiation of Dendritic Cell Progenitors

    Mary A. Antonysamy;William C. Fanslow;Fumin Fu;Wei Li

  • Molecular characterization of murine and human OX40/OX40 ligand systems: identification of a human OX40 ligand as the HTLV-1-regulated protein gp34.

    P.R. Baum;R.B. Gayle rd;F. Ramsdell;S. Srinivasan

  • CD40 Ligand Is Required for Protective Cell-Mediated Immunity to Leishmania major

    Kim A Campbell;Pamela J Ovendale;Mary K Kennedy;William C Fanslow

  • Human B cell proliferation and Ig secretion induced by recombinant CD40 ligand are modulated by soluble cytokines.

    R J Armitage;B M Macduff;M K Spriggs;W C Fanslow

  • CD40 ligand and its role in X-linked hyper-IgM syndrome.

    Robin E. Callard;Richard J. Armitage;William C. Fanslow;Melanie K. Spriggs

  • The CD39 lymphoid cell activation antigen. Molecular cloning and structural characterization.

    C R Maliszewski;G J Delespesse;M A Schoenborn;R J Armitage

  • Regulation of alloreactivity in vivo by a soluble form of the interleukin-1 receptor.

    William C. Fanslow;John E. Sims;Helmut Sassenfeld;Philip J. Morrissey

  • Inhibition of Human B-Cell Lymphoma Growth by CD40 Stimulation

    Satoshi Funakoshi;Dan L. Longo;Margaret Beckwith;Denise K. Conley

  • Structural characteristics of CD40 ligand that determine biological function

    William C. Fanslow;Subhashini Srinivasan;Ray Paxton;Marylou G. Gibson

Frequent Co-Authors

Charles R. Maliszewski
Charles R. Maliszewski Amgen (United States)
Douglas Pat Cerretti
Douglas Pat Cerretti Amgen (United States)
Kenneth H. Grabstein
Kenneth H. Grabstein Corixa Corporation
Dan L. Longo
Dan L. Longo Harvard University
William J. Murphy
William J. Murphy Texas A&M University
Craig A. Smith
Craig A. Smith Vanderbilt University
David Cosman
David Cosman Amgen (United States)
Dennis D. Taub
Dennis D. Taub George Washington University
Neal G. Copeland
Neal G. Copeland The University of Texas MD Anderson Cancer Center
Nancy A. Jenkins
Nancy A. Jenkins The University of Texas MD Anderson Cancer Center

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