What is he best known for?
The fields of study he is best known for:
The scientist’s investigation covers issues in DNA replication, Cell biology, Molecular biology, Genetics and Origin recognition complex.
His research on DNA replication concerns the broader DNA.
The Cell biology study combines topics in areas such as Chromatin and Cell cycle.
His Molecular biology study also includes
- Embryonic stem cell together with Stem cell,
- Transcription factor that connect with fields like Proto-oncogene tyrosine-protein kinase Src.
His research in Origin recognition complex tackles topics such as Pre-replication complex which are related to areas like DNA replication factor CDT1, Licensing factor and DNA re-replication.
His Eukaryotic DNA replication research is multidisciplinary, incorporating perspectives in DNA polymerase delta and DNA polymerase II.
His most cited work include:
- TEAD/TEF transcription factors utilize the activation domain of YAP65, a Src/Yes-associated protein localized in the cytoplasm (505 citations)
- Transcription factor TEAD4 specifies the trophectoderm lineage at the beginning of mammalian development. (381 citations)
- Regulation of gene expression at the beginning of mammalian development. (267 citations)
What are the main themes of his work throughout his whole career to date?
His main research concerns Cell biology, DNA replication, Genetics, Origin recognition complex and Molecular biology.
His work carried out in the field of Cell biology brings together such families of science as Chromatin, Cellular differentiation and ORC1.
As a part of the same scientific study, Melvin L. DePamphilis usually deals with the Chromatin, concentrating on Enhancer and frequently concerns with Maternal to zygotic transition, Regulation of gene expression and Psychological repression.
His DNA replication research includes themes of DNA polymerase II, DNA clamp and DNA polymerase.
His Origin recognition complex research is multidisciplinary, relying on both Pre-replication complex, Replication factor C, DNA replication factor CDT1 and Control of chromosome duplication.
In his study, Transcription is strongly linked to Transcription factor, which falls under the umbrella field of Molecular biology.
He most often published in these fields:
- Cell biology (43.07%)
- DNA replication (39.42%)
- Genetics (35.77%)
What were the highlights of his more recent work (between 2010-2021)?
- Cell biology (43.07%)
- Cancer research (5.84%)
- Cellular differentiation (10.22%)
In recent papers he was focusing on the following fields of study:
Melvin L. DePamphilis mostly deals with Cell biology, Cancer research, Cellular differentiation, Genetics and DNA replication.
His research integrates issues of Endoreduplication and DNA re-replication, Origin recognition complex, Eukaryotic DNA replication in his study of Cell biology.
His study in Origin recognition complex is interdisciplinary in nature, drawing from both Pre-replication complex, Origin of replication, Protein subunit, Chromatin and Nuclear transport.
In his research on the topic of Eukaryotic DNA replication, Control of chromosome duplication is strongly related with Mitotic cell cycle.
DNA replication is a subfield of DNA that Melvin L. DePamphilis explores.
His work deals with themes such as Molecular biology and Genome instability, which intersect with Cell cycle.
Between 2010 and 2021, his most popular works were:
- TEAD4 establishes the energy homeostasis essential for blastocoel formation (51 citations)
- Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition) (38 citations)
- Checkpoint Kinase 1 Prevents Cell Cycle Exit Linked to Terminal Cell Differentiation (33 citations)
In his most recent research, the most cited papers focused on:
His primary areas of investigation include Cell biology, Autolysosome, Autophagy, Eukaryotic DNA replication and Polo-like kinase.
His biological study spans a wide range of topics, including Molecular biology, Origin recognition complex and Transcription factor.
The concepts of his Molecular biology study are interwoven with issues in Embryonic stem cell, TEAD4, Blastocyst, Mitochondrion and Embryo.
His Origin recognition complex research incorporates elements of Replication factor C, Replisome, Pre-replication complex, DNA replication checkpoint and Regulator.
His Eukaryotic DNA replication research integrates issues from Endoreduplication, Mitotic exit, Mitotic cell cycle and Phosphorylation.
Melvin L. DePamphilis works mostly in the field of Polo-like kinase, limiting it down to concerns involving Mitosis and, occasionally, Cellular differentiation and Cyclin-dependent kinase 6.
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