Ronald Wetzel

Overview

Best Publications

• Recombinant immunoglobulin preparations, methods for their preparation, DNA sequences, expression vectors and recombinant host cells therefor

  Shmuel Cabilly;William Evans Holmes;Ronald Burnell Wetzel;Herbert Louis Heyneker

  1473
  Citations

• Huntington's disease age-of-onset linked to polyglutamine aggregation nucleation

  Songming Chen;Frank A. Ferrone;Ronald Wetzel

  660
  Citations

• Eukaryotic Proteasomes Cannot Digest Polyglutamine Sequences and Release Them during Degradation of Polyglutamine-Containing Proteins

  Prasanna Venkatraman;Ronald Wetzel;Motomasa Tanaka;Nobuyuki Nukina

  526
  Citations

• Polyglutamine disruption of the huntingtin exon 1 N terminus triggers a complex aggregation mechanism

  Ashwani K Thakur;Murali Jayaraman;Rakesh Mishra;Monika Thakur

  497
  Citations

• Disulfide bond engineered into T4 lysozyme: stabilization of the protein toward thermal inactivation

  LJ Perry;R Wetzel

  489
  Citations

• Seeding Specificity in Amyloid Growth Induced by Heterologous Fibrils

  Brian O'Nuallain;Angela D. Williams;Per Westermark;Ronald Wetzel

  479
  Citations

• Mapping Aβ amyloid fibril secondary structure using scanning proline mutagenesis

  Angela D. Williams;Erik Portelius;Indu Kheterpal;Jun-tao Guo

  469
  Citations

• Physical, morphological and functional differences between ph 5.8 and 7.4 aggregates of the Alzheimer's amyloid peptide Abeta.

  Stephen J. Wood;Beverly Maleeff;Timothy Hart;Ronald Wetzel

  452
  Citations

• Polymorphism in the intermediates and products of amyloid assembly.

  Ravindra Kodali;Ronald Wetzel

  447
  Citations

• Aggregated polyglutamine peptides delivered to nuclei are toxic to mammalian cells

  Wen Yang;John R. Dunlap;Richard B. Andrews;Ronald Wetzel

  441
  Citations

• Prolines and amyloidogenicity in fragments of the Alzheimer's peptide beta/A4.

  Stephen J. Wood;Ronald Wetzel;John D. Martin;Mark R. Hurle

  437
  Citations

• A role for destabilizing amino acid replacements in light-chain amyloidosis

  Mark R. Hurle;Larry R. Helms;Lin Li;Winnie Chan

  432
  Citations

• Conformational Abs recognizing a generic amyloid fibril epitope.

  Brian O'Nuallain;Ronald Wetzel

  431
  Citations

• Amyloid-like features of polyglutamine aggregates and their assembly kinetics.

  Songming Chen;Valerie Berthelier;J Bradley Hamilton;Brian O'Nuallain

  424
  Citations

• Polyglutamine aggregation behavior in vitro supports a recruitment mechanism of cytotoxicity.

  Songming Chen;Valerie Berthelier;Wen Yang;Ronald Wetzel

  411
  Citations

• Generation of antibody activity from immunoglobulin polypeptide chains produced in Escherichia coli

  S Cabilly;A D Riggs;H Pande;J E Shively

  377
  Citations

• Serines 13 and 16 Are Critical Determinants of Full-Length Human Mutant Huntingtin Induced Disease Pathogenesis in HD Mice

  Xiaofeng Gu;Xiaofeng Gu;Erin R. Greiner;Erin R. Greiner;Rakesh Mishra;Ravindra Kodali

  362
  Citations

• Absence of behavioral abnormalities and neurodegeneration in vivo despite widespread neuronal huntingtin inclusions

  Elizabeth J. Slow;Rona K. Graham;Alexander P. Osmand;Rebecca S. Devon

  362
  Citations

• Amyloid adhesins are abundant in natural biofilms.

  Poul Larsen;Jeppe Lund Nielsen;Morten Simonsen Dueholm;Ronald Wetzel

  358
  Citations

• Kinetics and thermodynamics of amyloid fibril assembly

  Ronald Wetzel

  356
  Citations