George L. Kenyon

Research.com Recognitions

• 1990 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Best Publications

• Structural identification of autoinducer of Photobacterium fischeri luciferase.

  A Eberhard;A L Burlingame;C Eberhard;G L Kenyon

  1403
  Citations

• Inhibition of the HIV-1 protease by fullerene derivatives: model building studies and experimental verification

  Simon H. Friedman;Dianne L. DeCamp;Rint P. Sijbesma;Gordana Srdanov

  1319
  Citations

• Synthesis of a fullerene derivative for the inhibition of HIV enzymes

  R. Sijbesma;G. Srdanov;F. Wudl;J. A. Castoro

  683
  Citations

• In Vitro Antimalarial Activity of Chalcones and Their Derivatives

  Rongshi Li;George L. Kenyon;Fred E. Cohen;Xiaowu Chen

  571
  Citations

• Simple alkanethiol groups for temporary blocking of sulfhydryl groups of enzymes.

  D J Smith;E T Maggio;G L Kenyon

  441
  Citations

• The Enolase Superfamily: A General Strategy for Enzyme-Catalyzed Abstraction of the α-Protons of Carboxylic Acids†

  Patricia C. Babbitt;Miriam S. Hasson;Miriam S. Hasson;Joseph E. Wedekind;Joseph E. Wedekind;David R.J. Palmer

  435
  Citations

• Optimizing the binding of fullerene inhibitors of the HIV-1 protease through predicted increases in hydrophobic desolvation.

  Simon H. Friedman;Padma S. Ganapathi;Yves Rubin;George L. Kenyon

  295
  Citations

• Ancestry of the 4-chlorobenzoate dehalogenase: analysis of amino acid sequence identities among families of acyl:adenyl ligases, enoyl-CoA hydratases/isomerases, and acyl-CoA thioesterases.

  Patricia C. Babbitt;George L. Kenyon;Brian M. Martin;Hugues Charest

  289
  Citations

• [40] Novel sulfhydryl reagents

  George L. Kenyon;Thomas W. Bruice

  260
  Citations

• The Crystal Structure of Benzoylformate Decarboxylase at 1.6 Å Resolution: Diversity of Catalytic Residues in Thiamin Diphosphate-Dependent Enzymes†,‡

  Miriam S. Hasson;Angelika Muscate;Michael J. McLeish;Lena S. Polovnikova

  241
  Citations

• Mechanism of the reaction catalyzed by acetoacetate decarboxylase. Importance of lysine 116 in determining the pKa of active-site lysine 115.

  Lane A. Highbarger;John A. Gerlt;George L. Kenyon

  224
  Citations

• Electrophilic catalysis can explain the unexpected acidity of carbon acids in enzyme-catalyzed reactions

  John Alan Gerlt;John W. Kozarich;George L. Kenyon;Paul G. Gassman

  223
  Citations

• On the specificity of creatine kinase. New glycocyamines and glycocyamine analogs related to creatine.

  Gerald L. Rowley;Arno L. Greenleaf;George L. Kenyon

  203
  Citations

• A functionally diverse enzyme superfamily that abstracts the alpha protons of carboxylic acids

  Patricia Clement Babbitt;Gregory T. Mrachko;Miriam Sarah Hasson;Gjalt W. Huisman

  193
  Citations

• Mechanism of the reaction catalyzed by mandelate racemase. 2. Crystal structure of mandelate racemase at 2.5-A resolution: identification of the active site and possible catalytic residues.

  David J. Neidhart;P. Lynne Howell;Gregory A. Petsko;Vincent M. Powers

  181
  Citations

• Mandelate racemase and muconate lactonizing enzyme are mechanistically distinct and structurally homologous

  David J. Neidhart;David J. Neidhart;David J. Neidhart;George L. Kenyon;John A. Gerlt;Gregory A. Petsko;Gregory A. Petsko;Gregory A. Petsko

  167
  Citations

• On the origin of enzymatic species

  Gregory A. Petsko;George L. Kenyon;John Alan Gerlt;Dagmar Ringe

  166
  Citations

• Structure-based design of parasitic protease inhibitors.

  Rongshi Li;Xiaowu Chen;Baoqing Gong;Paul M. Selzer

  166
  Citations

• The 2.1 A structure of Torpedo californica creatine kinase complexed with the ADP-Mg(2+)-NO(3)(-)-creatine transition-state analogue complex.

  Sushmita D Lahiri;Pan-Fen Wang;Patricia C Babbitt;Michael J McLeish

  164
  Citations

• Use of pH studies to elucidate the catalytic mechanism of rabbit muscle creatine kinase.

  Paul F. Cook;George L. Kenyon;W. Wallace Cleland

  153
  Citations