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Francisco B. Ortega

Francisco B. Ortega

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Medicine
Spain
2023

D-Index & Metrics

Medicine

D-Index
112
Citations
61283
World Ranking
5067
National Ranking
68

Research.com Recognitions

  • 2023 - Research.com Medicine in Spain Leader Award

Overview

Francisco B. Ortega is affiliated with the University of Granada in Spain. Their research primarily spans the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with significant contributions to several subfields including Physiology, Molecular Biology, Epidemiology, Endocrinology, Diabetes and Metabolism, and Cancer Research.

Ortega's work focuses on key topics such as Adipose Tissue and Metabolism, Adipokines, Inflammation, and Metabolic Diseases, Liver Disease Diagnosis and Treatment, Peroxisome Proliferator-Activated Receptors, Sulfur Compounds in Biology, Metabolism, Diabetes, and Cancer, as well as Diabetes and associated disorders.

The scientist has published extensively in notable venues including Biomedicine & Pharmacotherapy, EBioMedicine, Pharmacological Research, Nature Communications, and Molecular Therapy - Nucleic Acids. These journals feature multiple publications that reflect the evolution and scope of their research interests.

Frequent coauthors collaborating with Ortega include José Manuel Fernández-Real, Jèssica Latorre, José María Moreno-Navarrete, Aina Lluch, and Núria Oliveras-Cañellas. These collaborations have been central to numerous research outputs and reflect a networked approach to advancing scientific knowledge.

Key recent publications include:

  • Compounds that modulate AMPK activity and hepatic steatosis impact the biosynthesis of microRNAs required to maintain lipid homeostasis in hepatocytes, 2020, EBioMedicine
  • Adipose tissue cysteine dioxygenase type 1 is associated with an anti-inflammatory profile, impacting on systemic metabolic traits, 2022, EBioMedicine
  • Lysozyme is a component of the innate immune system linked to obesity associated-chronic low-grade inflammation and altered glucose tolerance, 2020, Clinical Nutrition
  • Adipose tissue knockdown of lysozyme reduces local inflammation and improves adipogenesis in high-fat diet-fed mice, 2021, Pharmacological Research
  • Permanent cystathionine-β-Synthase gene knockdown promotes inflammation and oxidative stress in immortalized human adipose-derived mesenchymal stem cells, enhancing their adipogenic capacity, 2020, Redox Biology

These publications address complex mechanisms involving metabolic regulation, inflammatory processes, and the molecular underpinnings of obesity and related disorders. They highlight an emphasis on understanding the role of enzymes, microRNAs, and inflammatory mediators within adipose tissue and liver physiology.

Best Publications

  • World Health Organization 2020 guidelines on physical activity and sedentary behaviour

    Fiona C. Bull;Salih S. Al-Ansari;Stuart Biddle;Katja Borodulin

  • Physical fitness in childhood and adolescence: a powerful marker of health

    F B Ortega;J R Ruiz;J R Ruiz;M J Castillo;M Sjöström

  • Accelerometer Data Collection and Processing Criteria to Assess Physical Activity and Other Outcomes: A Systematic Review and Practical Considerations

    Jairo H. Migueles;Cristina Cadenas-Sanchez;Ulf Ekelund;Ulf Ekelund;Christine Delisle Nyström

  • Role of Physical Activity and Sedentary Behavior in the Mental Health of Preschoolers, Children and Adolescents: A Systematic Review and Meta-Analysis.

    María Rodriguez-Ayllon;Cristina Cadenas-Sánchez;Fernando Estévez-López;Fernando Estévez-López;Nicolas E Muñoz

  • Predictive validity of health-related fitness in youth: a systematic review

    Jonatan R Ruiz;Jose Castro-Piñero;Enrique G Artero;Francisco B Ortega

  • 2020 WHO guidelines on physical activity and sedentary behaviour for children and adolescents aged 5–17 years: summary of the evidence

    Jean-Philippe Chaput;Jean-Philippe Chaput;Juana F. Willumsen;Fiona Bull;Roger Chou

  • Obesity and Cardiovascular Disease

    Francisco B. Ortega;Carl J. Lavie;Steven N. Blair

  • Field-based fitness assessment in young people: the ALPHA health-related fitness test battery for children and adolescents

    Jonatan R Ruiz;José Castro-Piñero;Vanesa España-Romero;Enrique G Artero

  • Muscular strength in male adolescents and premature death: cohort study of one million participants

    Francisco B Ortega;Karri Silventoinen;Per Tynelius;Finn Rasmussen

  • Criterion-related validity of field-based fitness tests in youth: a systematic review

    Jose Castro-Piñero;Enrique G Artero;Vanesa España-Romero;Francisco B Ortega

  • Physical fitness levels among European adolescents: The HELENA study

    Francisco B Ortega;Francisco B Ortega;Enrique G Artero;Jonatan R Ruiz;Jonatan R Ruiz;Vanesa España-Romero;Vanesa España-Romero

  • An Overview and Update on Obesity and the Obesity Paradox in Cardiovascular Diseases.

    Andrew Elagizi;Sergey Kachur;Carl J. Lavie;Salvatore Carbone

  • Relations of total physical activity and intensity to fitness and fatness in children: the European Youth Heart Study

    Jonatan R Ruiz;Nico S Rizzo;Anita Hurtig-Wennlöf;Francisco B Ortega

  • The intriguing metabolically healthy but obese phenotype: cardiovascular prognosis and role of fitness

    Francisco B. Ortega;Duck-chul Lee;Peter T. Katzmarzyk;Jonatan R. Ruiz;Jonatan R. Ruiz

  • Short sleep duration is associated with increased obesity markers in European adolescents: effect of physical activity and dietary habits. The HELENA study

    M Garaulet;F B Ortega;F B Ortega;J R Ruiz;J R Ruiz;J P Rey-López

  • Comparisons of leisure-time physical activity and cardiorespiratory fitness as predictors of all-cause mortality in men and women

    D.-C. Lee;X. Sui;F. B. Ortega;Y.-S. Kim

  • Obesity and Prevalence of Cardiovascular Diseases and Prognosis—The Obesity Paradox Updated

    Carl J. Lavie;Alban De Schutter;Parham Parto;Eiman Jahangir

  • Assessing muscular strength in youth: usefulness of standing long jump as a general index of muscular fitness.

    José Castro-Piñero;Francisco B Ortega;Enrique G Artero;Maria J Girela-Rejón

  • Muscular Strength as a Predictor of All-Cause Mortality in an Apparently Healthy Population: A Systematic Review and Meta-Analysis of Data From Approximately 2 Million Men and Women

    Antonio García-Hermoso;Iván Cavero-Redondo;Robinson Ramírez-Vélez;Jonatan R. Ruiz

  • Reliability of health-related physical fitness tests in European adolescents. The HELENA Study

    F. B. Ortega;F. B. Ortega;E. G. Artero;J. R. Ruiz;G. Vicente-Rodriguez

Frequent Co-Authors

Jonatan R. Ruiz
Jonatan R. Ruiz University of Granada
Luis A. Moreno
Luis A. Moreno University of Zaragoza
Michael Sjöström
Michael Sjöström Karolinska Institute
Marcela González-Gross
Marcela González-Gross Technical University of Madrid
Dénes Molnár
Dénes Molnár University of Pecs
Kurt Widhalm
Kurt Widhalm Medical University of Vienna
Yannis Manios
Yannis Manios Harokopio University
Frédéric Gottrand
Frédéric Gottrand University of Lille
Inge Huybrechts
Inge Huybrechts International Agency For Research On Cancer
Andrés Catena
Andrés Catena University of Granada

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