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Chemistry

D-Index
58
Citations
9432
World Ranking
10858
National Ranking
781

Biology and Biochemistry

D-Index
58
Citations
9419
World Ranking
13428
National Ranking
956

Overview

Rolf Jansen is affiliated with the Helmholtz Centre for Infection Research in Germany. Their research focuses on various aspects of biochemistry, genetics, molecular biology, and medicine, with specific attention to subfields such as pharmacology, molecular biology, molecular medicine, biotechnology, and infectious diseases.

The scientist's work frequently addresses topics including antibiotic resistance in bacteria, antibiotics pharmacokinetics and efficacy, microbial natural products and biosynthesis, phytochemistry and bioactivity studies, molecular spectroscopy and chirality, bacterial biofilms and quorum sensing, and marine sponges and natural products.

They have published extensively in several research venues, with multiple papers in Pharmaceutics, Antibiotics, and Microbiology Spectrum. Other publication venues include bioRxiv (Cold Spring Harbor Laboratory) and PLoS neglected tropical diseases. Their recent papers cover a range of studies on Corallopyronin A and antimicrobial research. Some of these are:

  • Corallopyronin A for short-course anti-wolbachial, macrofilaricidal treatment of filarial infections (2020, PLoS neglected tropical diseases)
  • Corallopyronin A: antimicrobial discovery to preclinical development (2022, Natural Product Reports)
  • Pharmacokinetics and Pharmacodynamics (PK/PD) of Corallopyronin A against Methicillin-Resistant Staphylococcus aureus (2022, Pharmaceutics)
  • Solubility and Stability Enhanced Oral Formulations for the Anti-Infective Corallopyronin A (2020, Pharmaceutics)
  • Amidochelocardin Overcomes Resistance Mechanisms Exerted on Tetracyclines and Natural Chelocardin (2020, Antibiotics)

Jansen collaborates frequently with colleagues such as Rolf Müller, Marc Stadler, Thomas Hesterkamp, Stephan Hüttel, and Jennifer Herrmann. These collaborations reflect joint contributions across microbiology and pharmacological research areas.

Best Publications

  • Fungal endophytes and bioprospecting

    T.S. Suryanarayanan;N. Thirunavukkarasu;M.B. Govindarajulu;F. Sasse

  • The RNA Polymerase “Switch Region” Is a Target for Inhibitors

    Jayanta Mukhopadhyay;Kalyan Das;Kalyan Das;Sajida Ismail;Sajida Ismail;David Koppstein;David Koppstein

  • Opening and Closing of the Bacterial RNA Polymerase Clamp

    Anirban Chakraborty;Dongye Wang;Yon W. Ebright;You Korlann

  • Ganomycins A and B, new antimicrobial farnesyl hydroquinones from the basidiomycete Ganoderma pfeifferi.

    Ramzi A. A. Mothana;Rolf Jansen;Wolf-Dieter Jülich;Ulrike Lindequist

  • Apicularens A and B, new cytostatic macrolides from Chondromyces species (myxobacteria): production, physico-chemical and biological properties.

    Brigitte Kunze;Rolf Jansen;Florenz Sasse;Gerhard Höfle

  • New target for inhibition of bacterial RNA polymerase: ‘switch region’

    Aashish Srivastava;Meliza Talaue;Shuang Liu;David Degen

  • Fatty acids with antibacterial activity from the cyanobacterium Oscillatoria redekei HUB 051

    Sabine Mundt;Susann Kreitlow;Rolf Jansen

  • Structural, functional, and genetic analysis of sorangicin inhibition of bacterial RNA polymerase

    Elizabeth A Campbell;Olga Pavlova;Olga Pavlova;Nikolay Zenkin;Fred Leon

  • 7-O-Malonyl Macrolactin A, a New Macrolactin Antibiotic from Bacillus subtilis Active against Methicillin-Resistant Staphylococcus aureus, Vancomycin-Resistant Enterococci, and a Small-Colony Variant of Burkholderia cepacia

    Magally Romero-Tabarez;Rolf Jansen;Marita Sylla;Heinrich Lünsdorf

  • The sorangicins, novel and powerful inhibitors of eubacterial RNA polymerase isolated from myxobacteria.

    Herbert Irschik;Rolf Jansen;Klaus Gerth;Gerhardt Höfle

  • Streptococcus mutans inhibits Candida albicans hyphal formation by the fatty acid signaling molecule trans-2-decenoic acid (SDSF).

    Ramiro Vílchez;André Lemme;Britta Ballhausen;Verena Thiel

  • Chondramides A~D, New Antifungal and Cytostatic Depsipeptides from Chondromyces crocatus(Myxobacteria)Production, Physico-chemical and Biological Properties

    Brigitte Kunze;Rolf Jansen;Florenz Sasse;Gerhard Höfle

  • Antiviral lanostanoid triterpenes from the fungus Ganoderma pfeifferi

    R.A.A Mothana;R.A.A Mothana;N.A Awadh Ali;N.A Awadh Ali;R Jansen;U Wegner

  • Correlating chemical diversity with taxonomic distance for discovery of natural products in myxobacteria.

    Thomas Hoffmann;Daniel Krug;Nisa Bozkurt;Srikanth Duddela

  • Pinensins: The First Antifungal Lantibiotics

    Kathrin I. Mohr;Carsten Volz;Rolf Jansen;Victor Wray

  • The corallopyronins, new inhibitors of bacterial RNA synthesis from Myxobacteria.

    H. Irschik;R. Jansen;G. Höfle;K. Gerth

  • Marinoquinolines A-F, pyrroloquinolines from Ohtaekwangia kribbensis (Bacteroidetes).

    Patrick W Okanya;Kathrin I Mohr;Klaus Gerth;Rolf Jansen

  • Stereochemical Determination and Complex Biosynthetic Assembly of Etnangien, a Highly Potent RNA Polymerase Inhibitor from the Myxobacterium Sorangium cellulosum

    Dirk Menche;Fatih Arikan;Olena Perlova;Nicole Horstmann

  • Rescue of Progranulin Deficiency Associated with Frontotemporal Lobar Degeneration by Alkalizing Reagents and Inhibition of Vacuolar ATPase

    A. Capell;S. Liebscher;K. Fellerer;N. Brouwers

  • The myxalamids, new antibiotics from Myxococcus xanthus (Myxobacterales). I. Production, physico-chemical and biological properties, and mechanism of action.

    K. Gerth;R. Jansen;G. Reifenstahl;G. Höfle

Frequent Co-Authors

Gerhard Höfle
Gerhard Höfle Helmholtz Centre for Infection Research
Hans Reichenbach
Hans Reichenbach University of California, Los Angeles
Klaus Gerth
Klaus Gerth Helmholtz Centre for Infection Research
Rolf Müller
Rolf Müller Saarland University
Florenz Sasse
Florenz Sasse Technische Universität Braunschweig
Andreas Kirschning
Andreas Kirschning University of Hannover
Marc Stadler
Marc Stadler Helmholtz Centre for Infection Research
Victor Wray
Victor Wray Heinrich Heine University Düsseldorf
Gerhard Hunsmann
Gerhard Hunsmann University of Göttingen
Volker Huch
Volker Huch Saarland University

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