D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 51 Citations 8,975 141 World Ranking 9376 National Ranking 4142

Overview

What is he best known for?

The fields of study he is best known for:

  • Enzyme
  • Cancer
  • Gene

His primary areas of investigation include Pharmacology, Stereochemistry, Epothilone, Virology and Epothilones. His Pharmacology research is multidisciplinary, incorporating perspectives in Etoposide, IC50, Paclitaxel and Transplantation. His study in the field of Intramolecular force and Indole test is also linked to topics like Simple, Glycal and Staurosporine.

In his research, Suzuki reaction is intimately related to Total synthesis, which falls under the overarching field of Epothilone. His Virology study integrates concerns from other disciplines, such as Peripheral blood mononuclear cell, In vitro and Gp41. His work in Graph paper tackles topics such as Applied mathematics which are related to areas like Product.

His most cited work include:

  • Quantitative analysis of dose-effect relationships: the combined effects of multiple drugs or enzyme inhibitors (5663 citations)
  • Drug Combination Studies and Their Synergy Quantification Using the Chou-Talalay Method (2856 citations)
  • Human neutralizing monoclonal antibodies of the IgG1 subtype protect against mucosal simian-human immunodeficiency virus infection. (832 citations)

What are the main themes of his work throughout his whole career to date?

His main research concerns Pharmacology, Stereochemistry, In vitro, Cytotoxicity and Virology. The various areas that Ting-Chao Chou examines in his Pharmacology study include Toxicity, Paclitaxel and Immunology. His Stereochemistry research incorporates elements of Biological activity, Topoisomerase and Chemical synthesis.

His biological study deals with issues like Cell growth, which deal with fields such as Cancer research and Cancer. His Virus research includes themes of Epitope, Alpha interferon and Monoclonal antibody. Drug connects with themes related to Combination index in his study.

He most often published in these fields:

  • Pharmacology (25.58%)
  • Stereochemistry (26.74%)
  • In vitro (20.93%)

What were the highlights of his more recent work (between 2007-2021)?

  • Cell growth (15.12%)
  • Cancer research (11.63%)
  • Pharmacology (25.58%)

In recent papers he was focusing on the following fields of study:

Ting-Chao Chou mostly deals with Cell growth, Cancer research, Pharmacology, Cancer and In vitro. His Pharmacology research is mostly focused on the topic Drug. Ting-Chao Chou focuses mostly in the field of In vitro, narrowing it down to topics relating to Nitrogen mustard and, in certain cases, Chemical synthesis.

His Cytotoxicity research includes elements of Acridine and Stereochemistry. Ting-Chao Chou works on Stereochemistry which deals in particular with Pharmacophore. Ting-Chao Chou has researched Internal medicine in several fields, including Combination index and Endocrinology.

Between 2007 and 2021, his most popular works were:

  • Drug Combination Studies and Their Synergy Quantification Using the Chou-Talalay Method (2856 citations)
  • Preclinical versus clinical drug combination studies. (166 citations)
  • Synergistic combination of microtubule targeting anticancer fludelone with cytoprotective panaxytriol derived from panax ginseng against MX-1 cells in vitro: experimental design and data analysis using the combination index method. (75 citations)

In his most recent research, the most cited papers focused on:

  • Enzyme
  • Cancer
  • Gene

His primary areas of study are In vitro, Biochemistry, Cell growth, Cancer research and Cytotoxicity. His In vitro study combines topics in areas such as Antagonism, Panaxytriol, Ginseng and Stereochemistry. The Thiazole research Ting-Chao Chou does as part of his general Stereochemistry study is frequently linked to other disciplines of science, such as Multiple modes, therefore creating a link between diverse domains of science.

His Biochemistry research focuses on Nitrogen mustard and how it connects with Chemical synthesis. His research integrates issues of Epothilone, Nude mouse, Epothilones, Therapeutic effect and Natural product in his study of Cell growth. His research in Cancer research intersects with topics in Anaplastic thyroid cancer, Thyroid cancer, Paclitaxel, Doxorubicin and Cell cycle.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Quantitative analysis of dose-effect relationships: the combined effects of multiple drugs or enzyme inhibitors

Ting Chao Chou;Paul Talalay.
Advances in Enzyme Regulation (1984)

7235 Citations

Drug Combination Studies and Their Synergy Quantification Using the Chou-Talalay Method

Ting-Chao Chou.
Cancer Research (2010)

3767 Citations

Human neutralizing monoclonal antibodies of the IgG1 subtype protect against mucosal simian-human immunodeficiency virus infection.

Timothy W. Baba;Vladimir Liska;Regina Hofmann-Lehmann;Josef Vlasak.
Nature Medicine (2000)

1077 Citations

Analysis of combined drug effects: a new look at a very old problem

Ting Chao Chou;Paul Talalay.
Trends in Pharmacological Sciences (1983)

629 Citations

Computerized Quantitation of Synergism and Antagonism of Taxol, Topotecan, and Cisplatin Against Human Teratocarcinoma Cell Growth: a Rational Approach to Clinical Protocol Design

Ting-Chao Chou;Robert J. Motzer;Youzhi Tong;George J. Bosl.
Journal of the National Cancer Institute (1994)

572 Citations

Generalized Equations for the Analysis of Inhibitions of Michaelis‐Menten and Higher‐Order Kinetic Systems with Two or More Mutually Exclusive and Nonexclusive Inhibitors

Ting‐Chao ‐C Chou;Paul Talalay.
FEBS Journal (2005)

474 Citations

Irinotecan is an active agent in untreated patients with metastatic colorectal cancer.

J. A. Conti;N. E. Kemeny;L. B. Saltz;Ying Huang.
Journal of Clinical Oncology (1996)

396 Citations

Derivation and properties of Michaelis-Menten type and Hill type equations for reference ligands☆

Ting-Chao Chou.
Journal of Theoretical Biology (1976)

393 Citations

Ribavirin antagonizes the effect of azidothymidine on HIV replication

Markus W. Vogt;Kevan L. Hartshorn;Phillip A. Furman;Ting-Chao Chou.
Science (1987)

350 Citations

A simple generalized equation for the analysis of multiple inhibitions of Michaelis-Menten kinetic systems.

T C Chou;P Talaly.
Journal of Biological Chemistry (1977)

323 Citations

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