World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
72
Citations
33494
World Ranking
6119
National Ranking
2874

Overview

Ting-Chao Chou is affiliated with the Memorial Sloan Kettering Cancer Center in the United States. Their research primarily spans medicine and biochemistry, genetics, and molecular biology, with significant focus areas including molecular biology, oncology, computational theory and mathematics, modeling and simulation, and radiology, nuclear medicine, and imaging.

Their recent publications demonstrate a concentration on computational drug discovery, cancer-related molecular pathways, gene regulatory network analysis, mathematical biology tumor growth, and statistical methods in clinical trials. Notable recent papers include:

  • Mathematical definitions of "additive effect of two (or more) drugs" and their synergism and/or antagonism based on mass-action law (MAL) algorithms for pharmacodynamics (PD), biodynamics (BD) and bioinformatics (BI) simulations (2022), published in The FASEB Journal
  • Functional biodynamics theory and algorithms for inhibitor or activator effectors and their interactions, by computer simulation bioinformatics for translational medicine (2022), published in The FASEB Journal
  • New Paradigm, Equations, Algorithm, and Computer software of Mass-action Law Based Biodynamics, Pharmacodynamics and Bioinformatics (MAL-BD/PD/BI) for Econo-Green Biomedical R&D and Regulatory Guidance (2021), published in The FASEB Journal
  • Efficacy of adavosertib therapy against anaplastic thyroid cancer (2021), published in Endocrine Related Cancer
  • P-124 Nivolumab plus ipilimumab as neoadjuvant therapy for potentially resectable hepatocellular carcinoma (2021), published in Annals of Oncology

Ting-Chao Chou frequently collaborates with several researchers, among whom are:

  • Shu-Fu Lin
  • Richard J. Wong
  • Yuling Lu
  • Ming-Hsien Wu
  • Wei-Yi Chen

Their works have been predominantly published in the following venues:

  • The FASEB Journal
  • Cancer Research
  • Endocrine Related Cancer
  • Cancers
  • Molecular Cancer Therapeutics

Main research topics along Ting-Chao Chou's work include:

  • Computational Drug Discovery Methods
  • Gene Regulatory Network Analysis
  • Cancer-related Molecular Pathways
  • Mathematical Biology Tumor Growth
  • Statistical Methods in Clinical Trials
  • DNA Repair Mechanisms
  • Cancer Treatment and Pharmacology

Best Publications

  • Quantitative analysis of dose-effect relationships: the combined effects of multiple drugs or enzyme inhibitors

    Ting Chao Chou;Paul Talalay

  • Drug Combination Studies and Their Synergy Quantification Using the Chou-Talalay Method

    Ting-Chao Chou

  • Human neutralizing monoclonal antibodies of the IgG1 subtype protect against mucosal simian-human immunodeficiency virus infection.

    Timothy W. Baba;Vladimir Liska;Regina Hofmann-Lehmann;Josef Vlasak

  • Analysis of combined drug effects: a new look at a very old problem

    Ting Chao Chou;Paul Talalay

  • Computerized Quantitation of Synergism and Antagonism of Taxol, Topotecan, and Cisplatin Against Human Teratocarcinoma Cell Growth: a Rational Approach to Clinical Protocol Design

    Ting-Chao Chou;Robert J. Motzer;Youzhi Tong;George J. Bosl

  • Generalized Equations for the Analysis of Inhibitions of Michaelis‐Menten and Higher‐Order Kinetic Systems with Two or More Mutually Exclusive and Nonexclusive Inhibitors

    Ting‐Chao ‐C Chou;Paul Talalay

  • Derivation and properties of Michaelis-Menten type and Hill type equations for reference ligands

    Ting-Chao Chou

  • Irinotecan is an active agent in untreated patients with metastatic colorectal cancer.

    J. A. Conti;N. E. Kemeny;L. B. Saltz;Ying Huang

  • A simple generalized equation for the analysis of multiple inhibitions of Michaelis-Menten kinetic systems.

    T C Chou;P Talaly

  • Ribavirin antagonizes the effect of azidothymidine on HIV replication

    Markus W. Vogt;Kevan L. Hartshorn;Phillip A. Furman;Ting-Chao Chou

  • Preclinical versus clinical drug combination studies.

    Ting-Chao Chou

  • Quantitation of chemopreventive synergism between (-)-epigallocatechin-3-gallate and curcumin in normal, premalignant and malignant human oral epithelial cells.

    Avi Khafif;Stimson P. Schantz;Ting Chao Chou;David Edelstein

  • Synergistic inhibition of human immunodeficiency virus in vitro by azidothymidine and recombinant alpha A interferon.

    K. L. Hartshorn;M. W. Vogt;Ting-Chao Chou;R. S. Blumberg

  • The Total Synthesis of Dynemicin A Leading to Development of a Fully Contained Bioreductively Activated Enediyne Prodrug

    Matthew D. Shair;Tae Young Yoon;Karoline K. Mosny;T. C. Chou

  • REMOTE EFFECTS IN MACROLIDE FORMATION THROUGH RING-FORMING OLEFIN METATHESIS : AN APPLICATION TO THE SYNTHESIS OF FULLY ACTIVE EPOTHILONE CONGENERS

    Dongfang Meng;Dai-Shi Su;Aaron Balog;Peter Bertinato

  • Synergistic Effects of New Chemopreventive Agents and Conventional Cytotoxic Agents against Human Lung Cancer Cell Lines

    Ariel F. Soriano;Barbara Helfrich;Daniel C. Chan;Lynn E. Heasley

  • Desoxyepothilone B: An efficacious microtubule-targeted antitumor agent with a promising in vivo profile relative to epothilone B

    Ting Chao Chou;Xiu Guo Zhang;Aaron Balog;Dai Shi Su

  • Total Synthesis of (–)‐Epothilone B: An Extension of the Suzuki Coupling Method and Insights into Structure–Activity Relationships of the Epothilones

    Dai Shi Su;Dongfang Meng;Dongfang Meng;Peter Bertinato;Aaron Balog

  • Synthesis of epothilones, intermediates thereto, analogues and uses thereof

    Samuel J. Danishefsky;Peter Bertinato;Dai-Shi Su;Dang Fang Meng

  • Pharmacokinetic Interactions Augment Toxicities of Sirolimus/Cyclosporine Combinations

    Hemangshu Podder;Stanislaw M. Stepkowski;Kimberly L. Napoli;James Clark

Frequent Co-Authors

Samuel J. Danishefsky
Samuel J. Danishefsky Columbia University
Martin S. Hirsch
Martin S. Hirsch Harvard Medical School
Te-Chang Lee
Te-Chang Lee Academia Sinica
Barry D. Kahan
Barry D. Kahan The University of Texas at Austin
Richard J. Wong
Richard J. Wong Memorial Sloan Kettering Cancer Center
Jack J. Fox
Jack J. Fox Memorial Sloan Kettering Cancer Center
Susan Band Horwitz
Susan Band Horwitz Albert Einstein College of Medicine
Yuman Fong
Yuman Fong City Of Hope National Medical Center
Lisa A. Cavacini
Lisa A. Cavacini University of Massachusetts Chan Medical School
Francis M. Sirotnak
Francis M. Sirotnak Memorial Sloan Kettering Cancer Center

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

The fields of biology and biochemistry open doors to a wide range of career pathways, many of which now offer online degree options. With the rapidly evolving landscape of health and life sciences, pursuing specialized degrees online provides flexibility and access to top programs.

For those interested in healthcare leadership, a doctorate in healthcare administration online prepares graduates for executive and management roles within hospitals and healthcare organizations. Similarly, if pharmacy is your passion, online pharmd programs for non pharmacists offer pathways into pharmaceutical research, regulatory affairs, or clinical practice—even for those without a bachelor's in pharmacy.

Alternatively, careers focusing on human movement and fitness can be accessed through an exercise science online degree or an online kinesiology bachelor's degree. These programs provide the knowledge and practical skills needed for roles in sports medicine, rehabilitation, coaching, or wellness.

Online degrees allow students to tailor their study to personal schedules, advancing their careers in biology, health, or fitness without sacrificing flexibility or educational quality.

Best Scientists Citing Ting-Chao Chou

Trending Scientists

Recently Published Articles