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Patrick Y. S. Lam

D-Index & Metrics

Chemistry

D-Index
51
Citations
12027
World Ranking
13803
National Ranking
1013

Patrick Y. S. Lam publication distribution in Chemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Chemistry in 2026. The highlighted bar marks where Patrick Y. S. Lam sits on this spectrum.

61–80 publications: 66 scientists 81–100 publications: 302 scientists 101–120 publications: 623 scientists 121–140 publications: 918 scientists 141–160 publications: 1,218 scientists 161–180 publications: 1,350 scientists 181–200 publications: 1,344 scientists 201–220 publications: 1,281 scientists 221–240 publications: 1,216 scientists 241–260 publications: 1,100 scientists 261–280 publications: 979 scientists 281–300 publications: 939 scientists 301–320 publications: 764 scientists 321–340 publications: 643 scientists 341–360 publications: 628 scientists 361–380 publications: 522 scientists 381–400 publications: 459 scientists 401–420 publications: 397 scientists 421–440 publications: 327 scientists 441–460 publications: 270 scientists 461–480 publications: 265 scientists 481–500 publications: 252 scientists 501–520 publications: 201 scientists 521–540 publications: 185 scientists 541–560 publications: 148 scientists 561–580 publications: 148 scientists 581–600 publications: 132 scientists 601–620 publications: 114 scientists 621–640 publications: 104 scientists 641–660 publications: 91 scientists 661–680 publications: 92 scientists 681–700 publications: 73 scientists 701–720 publications: 57 scientists 721–740 publications: 54 scientists 741–760 publications: 67 scientists 761–780 publications: 45 scientists 781–800 publications: 46 scientists 801–820 publications: 39 scientists 821–840 publications: 32 scientists 841–860 publications: 36 scientists 861–880 publications: 29 scientists 881–900 publications: 26 scientists 901–920 publications: 24 scientists 921–940 publications: 14 scientists 941–960 publications: 23 scientists 961–980 publications: 28 scientists 981–1,000 publications: 15 scientists 1,001–1,020 publications: 29 scientists 1,021–1,040 publications: 12 scientists 1,041–1,060 publications: 19 scientists 1,061–1,080 publications: 12 scientists 1,081–1,100 publications: 6 scientists 1,101–1,120 publications: 8 scientists 1,121–1,140 publications: 12 scientists 1,141–1,160 publications: 5 scientists 1,161–1,180 publications: 6 scientists 1,181–1,200 publications: 14 scientists 1,201–1,220 publications: 7 scientists 1,221–1,240 publications: 2 scientists 1,241–1,260 publications: 6 scientists 1,261–1,280 publications: 4 scientists 1,281–1,294 publications: 6 scientists 1,295+ publications: 100 scientists
61 publications 1,295+

This scientist: 156 publications — 16th percentile

16% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,295 publications or more.

Patrick Y. S. Lam D-index placement in Chemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Chemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Patrick Y. S. Lam sits on this spectrum.

40–41 D-Index: 289 scientists 42–43 D-Index: 612 scientists 44–45 D-Index: 808 scientists 46–47 D-Index: 776 scientists 48–49 D-Index: 835 scientists 50–51 D-Index: 861 scientists 52–53 D-Index: 872 scientists 54–55 D-Index: 933 scientists 56–57 D-Index: 1,051 scientists 58–59 D-Index: 930 scientists 60–61 D-Index: 882 scientists 62–63 D-Index: 834 scientists 64–65 D-Index: 731 scientists 66–67 D-Index: 775 scientists 68–69 D-Index: 683 scientists 70–71 D-Index: 646 scientists 72–73 D-Index: 561 scientists 74–75 D-Index: 501 scientists 76–77 D-Index: 437 scientists 78–79 D-Index: 388 scientists 80–81 D-Index: 354 scientists 82–83 D-Index: 292 scientists 84–85 D-Index: 275 scientists 86–87 D-Index: 254 scientists 88–89 D-Index: 235 scientists 90–91 D-Index: 185 scientists 92–93 D-Index: 192 scientists 94–95 D-Index: 155 scientists 96–97 D-Index: 163 scientists 98–99 D-Index: 125 scientists 100–101 D-Index: 105 scientists 102–103 D-Index: 105 scientists 104–105 D-Index: 112 scientists 106–107 D-Index: 88 scientists 108–109 D-Index: 68 scientists 110–111 D-Index: 69 scientists 112–113 D-Index: 65 scientists 114–115 D-Index: 79 scientists 116–117 D-Index: 61 scientists 118–119 D-Index: 44 scientists 120–121 D-Index: 37 scientists 122–123 D-Index: 40 scientists 124–125 D-Index: 33 scientists 126–127 D-Index: 26 scientists 128–129 D-Index: 34 scientists 130–131 D-Index: 35 scientists 132–133 D-Index: 25 scientists 134–135 D-Index: 27 scientists 136–137 D-Index: 17 scientists 138–139 D-Index: 16 scientists 140–141 D-Index: 20 scientists 142–143 D-Index: 20 scientists 144–145 D-Index: 15 scientists 146–147 D-Index: 9 scientists 148–149 D-Index: 9 scientists 150–151 D-Index: 16 scientists 152–153 D-Index: 11 scientists 154–155 D-Index: 9 scientists 156–157 D-Index: 3 scientists 158 D-Index: 3 scientists 159+ D-Index: 98 scientists
40 D-Index 159+

This scientist: 51 D-Index — 23rd percentile

23% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 159 D-Index or more.

Overview

Patrick Y. S. Lam is affiliated with Bristol-Myers Squibb in Germany. Their research spans multiple areas within the fields of Medicine and Chemistry, with a primary focus on Organic Chemistry, Epidemiology, Hepatology, Biochemistry, and Ecology.

The scientist's recent publications illustrate a broad engagement with both chemical synthesis and biomedical studies. These works include:

  • Advances in Carbon-Element Bond Construction under Chan-Lam Cross-Coupling Conditions: A Second Decade, 2020, published in Synthesis
  • Prevalence of simian malaria parasites in macaques of Singapore, 2021, published in PLoS neglected tropical diseases
  • Discovery of a first-in-class inhibitor of sulfide:quinone oxidoreductase that protects against adverse cardiac remodelling and heart failure, 2021, published in Cardiovascular Research
  • Discovery of a High Affinity, Orally Bioavailable Macrocyclic FXIa Inhibitor with Antithrombotic Activity in Preclinical Species, 2020, published in Journal of Medicinal Chemistry
  • Survey of rodent-borne pathogens in Singapore reveals the circulation of Leptospira spp., Seoul hantavirus, and Rickettsia typhi, 2022, published in Scientific Reports

Lam's research covers a range of topics including:

  • Hepatitis B Virus Studies
  • Hepatitis C virus research
  • Sulfur Compounds in Biology
  • Coagulation, Bradykinin, Polyphosphates, and Angioedema
  • Peptidase Inhibition and Analysis
  • Catalytic C-H Functionalization Methods
  • Catalytic Cross-Coupling Reactions

Frequent co-authors in Lam's work include:

  • Nicky Hwang
  • Yanming Du
  • Diyar Mailepessov
  • Lee Ching Ng
  • Michael R. Jackson

Publications by Lam have appeared in various scientific venues, predominantly:

  • Bioorganic & Medicinal Chemistry Letters
  • Synthesis
  • PLoS neglected tropical diseases
  • Cardiovascular Research
  • Scientific Reports

The interdisciplinary nature of Patrick Y. S. Lam's research integrates organic chemistry methodologies with medical and epidemiological investigations, highlighting work on viral hepatitis, biochemical pathways relating to sulfur compounds, and cardiovascular biology. This body of work reflects a combination of chemical synthesis approaches and biomedical applications.

Best Publications

  • New aryl/heteroaryl CN bond cross-coupling reactions via arylboronic acid/cupric acetate arylation

    Patrick Y.S Lam;Charles G Clark;Simon Saubern;Jessica Adams

  • Rational design of potent, bioavailable, nonpeptide cyclic ureas as HIV protease inhibitors

    PY Lam;PK Jadhav;CJ Eyermann;CN Hodge

  • Copper-Promoted Carbon-HeteroatomBond Cross-Coupling with Boronic Acids and Derivatives

    Jennifer X. Qiao;Patrick Y. S. Lam

  • Discovery of 1-(4-Methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,6,7-tetrahydro- 1H-pyrazolo[3,4-c]pyridine-3-carboxamide (Apixaban, BMS-562247), a Highly Potent, Selective, Efficacious, and Orally Bioavailable Inhibitor of Blood Coagulation Factor Xa.

    Donald J.P. Pinto;Michael J. Orwat;Stephanie Koch;Karen A. Rossi

  • Copper-catalyzed general CN and CO bond cross-coupling with arylboronic acid

    Patrick Y.S Lam;Guillaume Vincent;Charles G Clark;Sophie Deudon

  • Flexibility and function in HIV-1 protease

    Nicholson Lk;Yamazaki T;Torchia Da;Grzesiek S

  • Lactam-containing compounds and derivatives thereof as factor xa inhibitors

    Donald J.P. Pinto;Mimi L. Quan;Michael J. Orwat;Yun-Long Li

  • Copper-Promoted C−N Bond Cross-Coupling with Hypervalent Aryl Siloxanes and Room-Temperature N-Arylation with Aryl Iodide

    Patrick Y. S. Lam;Sophie Deudon;Kristin M. Averill;Renhua Li

  • Discovery of 1-(3'-aminobenzisoxazol-5'-yl)-3-trifluoromethyl-N-[2-fluoro-4- [(2'-dimethylaminomethyl)imidazol-1-yl]phenyl]-1H-pyrazole-5-carboxyamide hydrochloride (razaxaban), a highly potent, selective, and orally bioavailable factor Xa inhibitor.

    Mimi L. Quan;Patrick Y. S. Lam;Qi Han;Donald J. P. Pinto

  • Discovery of 1-[3-(aminomethyl)phenyl]-N-3-fluoro-2'-(methylsulfonyl)-[1,1'-biphenyl]-4-yl]-3-(trifluoromethyl)-1H-pyrazole-5-carboxamide (DPC423), a highly potent, selective, and orally bioavailable inhibitor of blood coagulation factor Xa.

    Donald J. P. Pinto;Michael J. Orwat;Shuaige Wang;John M. Fevig

  • Cyclic HIV protease inhibitors: synthesis, conformational analysis, P2/P2' structure-activity relationship, and molecular recognition of cyclic ureas.

    P. Y. S. Lam;Y. Ru;P. K. Jadhav;P. E. Aldrich

  • Copper-promoted/catalyzed CN and CO bond cross-coupling with vinylboronic acid and its utilities

    Patrick Y.S Lam;Guillaume Vincent;Damien Bonne;Charles G Clark

  • Copper promoted CN and CO bond cross-coupling with phenyl and pyridylboronates

    Dominic M.T. Chan;Kevin L. Monaco;Renhua Li;Damien Bonne

  • Inhibitors of factor Xa with a neutral P1 specificity group

    Robert Anthony Galemmo;Celia Dominguez;John Matthew Fevig;Qi Han

  • Factor xa inhibitors

    Mimi L. Quan;Patrick Y. Lam;Yunlong Li;Donald J. P. Pinto

  • Improved cyclic urea inhibitors of the HIV-1 protease: synthesis, potency, resistance profile, human pharmacokinetics and X-ray crystal structure of DMP 450

    Hodge Cn;Aldrich Pe;Bacheler Lt;Chang Ch

  • NMR and X-ray Evidence That the HIV Protease Catalytic Aspartyl Groups Are Protonated in the Complex Formed by the Protease and a Non-Peptide Cyclic Urea-Based Inhibitor

    Toshimasa Yamazaki;Linda K. Nicholson;Paul Wingfield;Stephen J. Stahl

  • Solid supported CN cross-coupling reactions

    Andrew P. Combs;Simon Saubern;Maria Rafalski;Patrick Y.S. Lam

  • N-Arylation of α-aminoesters with p-tolylboronic acid promoted by copper(II) acetate

    Patrick Y.S Lam;Damien Bonne;Guillaume Vincent;Charles G Clark

  • Molecular basis of HIV-1 protease drug resistance: structural analysis of mutant proteases complexed with cyclic urea inhibitors.

    P. J. Ala;E. E. Huston;R. M. Klabe;D. D. Mccabe

Frequent Co-Authors

Donald J. Cram
Donald J. Cram University of California, Los Angeles
Paul T. Wingfield
Paul T. Wingfield National Institutes of Health
Stephen J. Stahl
Stephen J. Stahl National Institutes of Health
Dennis A. Torchia
Dennis A. Torchia National Institutes of Health
Phil S. Baran
Phil S. Baran Scripps Research Institute

External Links

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Related Online Degrees & Career Pathways

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Career options in this field are varied. The forensic career paths include roles like forensic chemists, crime lab analysts, and toxicologists. These positions often require specialized knowledge that combines chemistry and criminal justice principles.

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Starting with an online associate degree in criminal justice is another accessible route to enter the field. This degree can provide foundational knowledge and prepare you for advanced studies or entry-level forensic positions.

Best Scientists Citing Patrick Y. S. Lam

John M. Louis

John M. Louis

National Institutes of Health

Publications: 27

Stephen L. Buchwald

Stephen L. Buchwald

MIT

Publications: 16

Ernesto Freire

Ernesto Freire

Johns Hopkins University

Publications: 15

Gerhard Klebe

Gerhard Klebe

Philipp University of Marburg

Publications: 15

Paul G. Mezey

Paul G. Mezey

Memorial University of Newfoundland

Publications: 15

Gregory Y.H. Lip

Gregory Y.H. Lip

University of Liverpool

Publications: 13

J. Andrew McCammon

J. Andrew McCammon

University of California, San Diego

Publications: 12

Celia A. Schiffer

Celia A. Schiffer

University of Massachusetts Chan Medical School

Publications: 12

M. Lakshmi Kantam

M. Lakshmi Kantam

Institute of Chemical Technology

Publications: 11

Anders Hallberg

Anders Hallberg

Uppsala University

Publications: 11

Glen E. Kellogg

Glen E. Kellogg

Virginia Commonwealth University

Publications: 11

Michael K. Gilson

Michael K. Gilson

University of California, San Diego

Publications: 11

Jeffrey I. Weitz

Jeffrey I. Weitz

McMaster University

Publications: 11

Ricardo A. Broglia

Ricardo A. Broglia

University of Milan

Publications: 11

Mats Larhed

Mats Larhed

Uppsala University

Publications: 10

Choung U. Kim

Choung U. Kim

Bristol-Myers Squibb (Germany)

Publications: 10

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