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Chemistry

D-Index
67
Citations
14184
World Ranking
7008
National Ranking
89

Overview

Mats Larhed is affiliated with Uppsala University in Sweden. Their research spans multiple fields primarily related to Medicine, Biochemistry, Genetics and Molecular Biology, and Chemistry. Within these broader areas, their work particularly engages with subfields such as Molecular Biology, Organic Chemistry, Oncology, Cellular and Molecular Neuroscience, and Pharmacology.

The core focus of Larhed's research involves topics like Peptidase Inhibition and Analysis, Neuropeptides and Animal Physiology, Receptor Mechanisms and Signaling, Chemical Synthesis and Analysis, Synthetic Organic Chemistry Methods, Asymmetric Synthesis and Catalysis, and Signaling Pathways in Disease.

Frequent co-authors in their publications include:

  • Mathias Hallberg
  • Johan Gising
  • Alfhild Grӧnbladh
  • Luke R. Odell
  • Hugo Gutiérrez-de-Terán

Larhed's research has been published repeatedly in several scientific journals, notably:

  • International Journal of Molecular Sciences
  • Bioorganic & Medicinal Chemistry
  • RSC Medicinal Chemistry
  • The Journal of Organic Chemistry
  • Synlett

Recent publications by Larhed include:

  • Heterodimeric Radiotracer Targeting PSMA and GRPR for Imaging of Prostate Cancer-Optimization of the Affinity towards PSMA by Linker Modification in Murine Model (2020) in Pharmaceutics
  • Structural Basis of Inhibition of Insulin-Regulated Aminopeptidase by a Macrocyclic Peptidic Inhibitor (2020) in ACS Medicinal Chemistry Letters
  • From Angiotensin IV to Small Peptidemimetics Inhibiting Insulin-Regulated Aminopeptidase (2020) in Frontiers in Pharmacology
  • Synthesis and In Vitro Biological Evaluation of Quinolinyl Pyrimidines Targeting Type II NADH-Dehydrogenase (NDH-2) (2022) in ACS Infectious Diseases
  • Macrocyclic peptidomimetics as inhibitors of insulin-regulated aminopeptidase (IRAP) (2020) in RSC Medicinal Chemistry

Best Publications

  • Microwave-accelerated homogeneous catalysis in organic chemistry.

    Mats Larhed;Christina Moberg;Anders Hallberg

  • Microwave-assisted high-speed chemistry: a new technique in drug discovery.

    Mats Larhed;Anders Hallberg

  • Microwave-Promoted Palladium-Catalyzed Coupling Reactions

    Mats Larhed;Anders Hallberg

  • Dimethylformamide as a carbon monoxide source in fast palladium-catalyzed aminocarbonylations of aryl bromides

    Yiqian Wan;Mathias Alterman;Mats Larhed;Anders Hallberg

  • Increasing rates and scope of reactions: sluggish amines in microwave-heated aminocarbonylation reactions under air.

    Johan Wannberg;Mats Larhed

  • Rapid microwave-assisted Suzuki coupling on solid-phase

    Mats Larhed;Gunnar Lindeberg;Anders Hallberg

  • In situ generation of carbon monoxide from solid molybdenum hexacarbonyl. A convenient and fast route to palladium-catalyzed carbonylation reactions.

    Nils-Fredrik K. Kaiser;and Anders Hallberg;Mats Larhed

  • Molybdenum Hexacarbonyl Mediated CO Gas-Free Carbonylative Reactions

    Luke R. Odell;Francesco Russo;Mats Larhed

  • High-speed heck reactions in ionic liquid with controlled microwave heating.

    Karl S. A. Vallin;Per Emilsson;Mats Larhed;Anders Hallberg

  • Lignin depolymerization to monophenolic compounds in a flow-through system

    Ivan Kumaniaev;Elena Subbotina;Jonas Sävmarker;Mats Larhed

  • Investigations on the 4-quinolone-3-carboxylic acid motif. 1. Synthesis and structure-activity relationship of a class of human immunodeficiency virus type 1 integrase inhibitors.

    Serena Pasquini;Claudia Mugnaini;Cristina Tintori;Maurizio Botta

  • Fast, Convenient, and Efficient Molybdenum‐Catalyzed Asymmetric Allylic Alkylation under Noninert Conditions: An Example of Microwave‐Promoted Fast Chemistry

    Nils‐Fredrik K. Kaiser;Ulf Bremberg;Mats Larhed;Christina Moberg

  • Microwave-Promoted Palladium(II)-Catalyzed C ? P Bond Formation by Using Arylboronic Acids or Aryltrifluoroborates

    Mounir Andaloussi;Jonas Lindh;Jonas Sävmarker;Per J.R. Sjöberg

  • Dioxygen-promoted regioselective oxidative heck arylations of electron-rich olefins with arylboronic acids.

    Murugaiah M S Andappan;Peter Nilsson;Henrik von Schenck;Mats Larhed

  • Highly regioselective, sequential, and multiple palladium-catalyzed arylations of vinyl ethers carrying a coordinating auxiliary: an example of a Heck triarylation process.

    Peter Nilsson;Mats Larhed;Anders Hallberg

  • Rapid Fluorous Stille Coupling Reactions Conducted under Microwave Irradiation

    Mats Larhed;Masahide Hoshino;Sabine Hadida;Dennis P. Curran

  • Microwave-enhanced aminocarbonylations in water.

    Xiongyu Wu;Mats Larhed

  • Microwave methods in organic synthesis

    Mats Larhed;Kristofer Olofssonq

  • High-Speed, Highly Fluorous Organic Reactions

    Kristofer Olofsson;Sun-Young Kim;Mats Larhed;Dennis P. Curran

  • The first ligand-modulated oxidative Heck vinylation. Efficient catalysis with molecular oxygen as palladium(0) oxidant

    Murugaiah M. S. Andappan;Peter Nilsson;Mats Larhed

  • Microwave-Assisted and Metal-Catalyzed Coupling Reactions

    Peter Nilsson;K Olofsson;Mats Larhed

Frequent Co-Authors

Anders Hallberg
Anders Hallberg Uppsala University
Peter M. Nilsson
Peter M. Nilsson Lund University
Anna Orlova
Anna Orlova Uppsala University
Vladimir Tolmachev
Vladimir Tolmachev Uppsala University
Christina Moberg
Christina Moberg Royal Institute of Technology
Bertil Samuelsson
Bertil Samuelsson Stockholm University
Sherry L. Mowbray
Sherry L. Mowbray Uppsala University
Johan Åqvist
Johan Åqvist Uppsala University
Jens Nørkær Sørensen
Jens Nørkær Sørensen Technical University of Denmark
Dennis P. Curran
Dennis P. Curran University of Pittsburgh

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