D-Index & Metrics Best Publications

Ernesto Freire

Johns Hopkins University
United States

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name Citations Publications World Ranking National Ranking

Chemistry D-index 98 Citations 27,514 256 World Ranking 787 National Ranking 354

Overview

What is he best known for?

The fields of study Ernesto Freire is best known for:

Enzyme
Gene
Amino acid

His work in the fields of Heat capacity, such as Thermodynamics, overlaps with other areas such as Chromatography. His multidisciplinary approach integrates Thermodynamics and Entropy (arrow of time) in his work. Ernesto Freire is involved in relevant fields of research such as Molecule and Dimer in the realm of Organic chemistry. His study in Organic chemistry extends to Molecule with its themes. A significant part of his Gene research incorporates Peptide sequence and Mutant studies. By researching both Mutant and Gene, Ernesto Freire produces research that crosses academic boundaries. His Virology research is linked to Human immunodeficiency virus (HIV) and Virus, among other subjects. Ernesto Freire conducted interdisciplinary study in his works that combined Virus and Virology. His Glycoprotein research extends to the thematically linked field of Biochemistry.

His most cited work include:

Isothermal titration calorimetry (500 citations)
Do enthalpy and entropy distinguish first in class from best in class? (402 citations)
Impact of Surface Polyethylene Glycol (PEG) Density on Biodegradable Nanoparticle Transport in Mucus ex Vivo and Distribution in Vivo (372 citations)

What are the main themes of his work throughout his whole career to date

His Human immunodeficiency virus (HIV) study which covers Virology that intersects with Virus. His work often combines Virus and Virology studies. He applies his multidisciplinary studies on Biochemistry and Chromatography in his research. In his works, Ernesto Freire undertakes multidisciplinary study on Chromatography and Biochemistry. His Organic chemistry study frequently draws connections between adjacent fields such as Molecule. As part of his studies on Molecule, he often connects relevant subjects like Organic chemistry. He performs multidisciplinary study in the fields of Thermodynamics and Calorimetry via his papers. In his research, he undertakes multidisciplinary study on Enzyme and Stereochemistry. Ernesto Freire applies his multidisciplinary studies on Stereochemistry and Enzyme in his research.

Ernesto Freire most often published in these fields:

Biochemistry (86.73%)
Organic chemistry (41.59%)
Thermodynamics (35.40%)

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

HIV-1 evades antibody-mediated neutralization through conformational masking of receptor-binding sites

Peter D. Kwong;Peter D. Kwong;Michael L. Doyle;Michael L. Doyle;David J. Casper;Claudia Cicala.
Nature (2002)

1111 Citations

Direct measurement of protein binding energetics by isothermal titration calorimetry

Stephanie Leavitt;Ernesto Freire.
Current Opinion in Structural Biology (2001)

903 Citations

Thermodynamics of structural stability and cooperative folding behavior in proteins.

Kenneth P. Murphy;Ernesto Freire.
Advances in Protein Chemistry (1992)

835 Citations

Isothermal titration calorimetry

Ernesto Freire;Obdulio L. Mayorga;Martin Straume.
Analytical Chemistry (1990)

756 Citations

Do enthalpy and entropy distinguish first in class from best in class

Ernesto Freire.
Drug Discovery Today (2008)

593 Citations

The heat capacity of proteins.

Javier Gómez;Vincent J. Hilser;Dong Xie;Ernesto Freire.
Proteins (1995)

529 Citations

Statistical mechanical deconvolution of thermal transitions in macromolecules. I. Theory and application to homogeneous systems

Ernesto Freire;Rodney L. Biltonen.
Biopolymers (1978)

471 Citations

Adding calorimetric data to decision making in lead discovery: a hot tip

John E. Ladbury;Gerhard Klebe;Ernesto Freire.
Nature Reviews Drug Discovery (2010)

443 Citations

Impact of Surface Polyethylene Glycol (PEG) Density on Biodegradable Nanoparticle Transport in Mucus ex Vivo and Distribution in Vivo.

Qingguo Xu;Laura M. Ensign;Laura M. Ensign;Nicholas J. Boylan;Arne Schön.
ACS Nano (2015)

401 Citations

The magnitude of the backbone conformational entropy change in protein folding.

J. Alejandro D'Aquino;Javier Gómez;Vincent J. Hilser;Kon Ho Lee;Kon Ho Lee.
Proteins (1996)

353 Citations

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Frequent Co-Authors

External Links

Personal Website for Ernesto Freire