His work in the fields of Heat capacity, such as Thermodynamics, overlaps with other areas such as Chromatography. His multidisciplinary approach integrates Thermodynamics and Entropy (arrow of time) in his work. Ernesto Freire is involved in relevant fields of research such as Molecule and Dimer in the realm of Organic chemistry. His study in Organic chemistry extends to Molecule with its themes. A significant part of his Gene research incorporates Peptide sequence and Mutant studies. By researching both Mutant and Gene, Ernesto Freire produces research that crosses academic boundaries. His Virology research is linked to Human immunodeficiency virus (HIV) and Virus, among other subjects. Ernesto Freire conducted interdisciplinary study in his works that combined Virus and Virology. His Glycoprotein research extends to the thematically linked field of Biochemistry.
His Human immunodeficiency virus (HIV) study which covers Virology that intersects with Virus. His work often combines Virus and Virology studies. He applies his multidisciplinary studies on Biochemistry and Chromatography in his research. In his works, Ernesto Freire undertakes multidisciplinary study on Chromatography and Biochemistry. His Organic chemistry study frequently draws connections between adjacent fields such as Molecule. As part of his studies on Molecule, he often connects relevant subjects like Organic chemistry. He performs multidisciplinary study in the fields of Thermodynamics and Calorimetry via his papers. In his research, he undertakes multidisciplinary study on Enzyme and Stereochemistry. Ernesto Freire applies his multidisciplinary studies on Stereochemistry and Enzyme in his research.
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HIV-1 evades antibody-mediated neutralization through conformational masking of receptor-binding sites
Peter D. Kwong;Peter D. Kwong;Michael L. Doyle;Michael L. Doyle;David J. Casper;Claudia Cicala.
Direct measurement of protein binding energetics by isothermal titration calorimetry
Stephanie Leavitt;Ernesto Freire.
Current Opinion in Structural Biology (2001)
Thermodynamics of structural stability and cooperative folding behavior in proteins.
Kenneth P. Murphy;Ernesto Freire.
Advances in Protein Chemistry (1992)
Isothermal titration calorimetry
Ernesto Freire;Obdulio L. Mayorga;Martin Straume.
Analytical Chemistry (1990)
Do enthalpy and entropy distinguish first in class from best in class
Drug Discovery Today (2008)
The heat capacity of proteins.
Javier Gómez;Vincent J. Hilser;Dong Xie;Ernesto Freire.
Statistical mechanical deconvolution of thermal transitions in macromolecules. I. Theory and application to homogeneous systems
Ernesto Freire;Rodney L. Biltonen.
Adding calorimetric data to decision making in lead discovery: a hot tip
John E. Ladbury;Gerhard Klebe;Ernesto Freire.
Nature Reviews Drug Discovery (2010)
Impact of Surface Polyethylene Glycol (PEG) Density on Biodegradable Nanoparticle Transport in Mucus ex Vivo and Distribution in Vivo.
Qingguo Xu;Laura M. Ensign;Laura M. Ensign;Nicholas J. Boylan;Arne Schön.
ACS Nano (2015)
The magnitude of the backbone conformational entropy change in protein folding.
J. Alejandro D'Aquino;Javier Gómez;Vincent J. Hilser;Kon Ho Lee;Kon Ho Lee.
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