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Irwin M. Chaiken

Irwin M. Chaiken

Drexel University
United States

D-Index & Metrics

Chemistry

D-Index
53
Citations
10849
World Ranking
13010
National Ranking
3436

Irwin M. Chaiken publication distribution in Chemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Chemistry in 2026. The highlighted bar marks where Irwin M. Chaiken sits on this spectrum.

61–80 publications: 66 scientists 81–100 publications: 302 scientists 101–120 publications: 623 scientists 121–140 publications: 918 scientists 141–160 publications: 1,218 scientists 161–180 publications: 1,350 scientists 181–200 publications: 1,344 scientists 201–220 publications: 1,281 scientists 221–240 publications: 1,216 scientists 241–260 publications: 1,100 scientists 261–280 publications: 979 scientists 281–300 publications: 939 scientists 301–320 publications: 764 scientists 321–340 publications: 643 scientists 341–360 publications: 628 scientists 361–380 publications: 522 scientists 381–400 publications: 459 scientists 401–420 publications: 397 scientists 421–440 publications: 327 scientists 441–460 publications: 270 scientists 461–480 publications: 265 scientists 481–500 publications: 252 scientists 501–520 publications: 201 scientists 521–540 publications: 185 scientists 541–560 publications: 148 scientists 561–580 publications: 148 scientists 581–600 publications: 132 scientists 601–620 publications: 114 scientists 621–640 publications: 104 scientists 641–660 publications: 91 scientists 661–680 publications: 92 scientists 681–700 publications: 73 scientists 701–720 publications: 57 scientists 721–740 publications: 54 scientists 741–760 publications: 67 scientists 761–780 publications: 45 scientists 781–800 publications: 46 scientists 801–820 publications: 39 scientists 821–840 publications: 32 scientists 841–860 publications: 36 scientists 861–880 publications: 29 scientists 881–900 publications: 26 scientists 901–920 publications: 24 scientists 921–940 publications: 14 scientists 941–960 publications: 23 scientists 961–980 publications: 28 scientists 981–1,000 publications: 15 scientists 1,001–1,020 publications: 29 scientists 1,021–1,040 publications: 12 scientists 1,041–1,060 publications: 19 scientists 1,061–1,080 publications: 12 scientists 1,081–1,100 publications: 6 scientists 1,101–1,120 publications: 8 scientists 1,121–1,140 publications: 12 scientists 1,141–1,160 publications: 5 scientists 1,161–1,180 publications: 6 scientists 1,181–1,200 publications: 14 scientists 1,201–1,220 publications: 7 scientists 1,221–1,240 publications: 2 scientists 1,241–1,260 publications: 6 scientists 1,261–1,280 publications: 4 scientists 1,281–1,294 publications: 6 scientists 1,295+ publications: 100 scientists
61 publications 1,295+

This scientist: 240 publications — 46th percentile

46% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,295 publications or more.

Irwin M. Chaiken D-index placement in Chemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Chemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Irwin M. Chaiken sits on this spectrum.

40–41 D-Index: 289 scientists 42–43 D-Index: 612 scientists 44–45 D-Index: 808 scientists 46–47 D-Index: 776 scientists 48–49 D-Index: 835 scientists 50–51 D-Index: 861 scientists 52–53 D-Index: 872 scientists 54–55 D-Index: 933 scientists 56–57 D-Index: 1,051 scientists 58–59 D-Index: 930 scientists 60–61 D-Index: 882 scientists 62–63 D-Index: 834 scientists 64–65 D-Index: 731 scientists 66–67 D-Index: 775 scientists 68–69 D-Index: 683 scientists 70–71 D-Index: 646 scientists 72–73 D-Index: 561 scientists 74–75 D-Index: 501 scientists 76–77 D-Index: 437 scientists 78–79 D-Index: 388 scientists 80–81 D-Index: 354 scientists 82–83 D-Index: 292 scientists 84–85 D-Index: 275 scientists 86–87 D-Index: 254 scientists 88–89 D-Index: 235 scientists 90–91 D-Index: 185 scientists 92–93 D-Index: 192 scientists 94–95 D-Index: 155 scientists 96–97 D-Index: 163 scientists 98–99 D-Index: 125 scientists 100–101 D-Index: 105 scientists 102–103 D-Index: 105 scientists 104–105 D-Index: 112 scientists 106–107 D-Index: 88 scientists 108–109 D-Index: 68 scientists 110–111 D-Index: 69 scientists 112–113 D-Index: 65 scientists 114–115 D-Index: 79 scientists 116–117 D-Index: 61 scientists 118–119 D-Index: 44 scientists 120–121 D-Index: 37 scientists 122–123 D-Index: 40 scientists 124–125 D-Index: 33 scientists 126–127 D-Index: 26 scientists 128–129 D-Index: 34 scientists 130–131 D-Index: 35 scientists 132–133 D-Index: 25 scientists 134–135 D-Index: 27 scientists 136–137 D-Index: 17 scientists 138–139 D-Index: 16 scientists 140–141 D-Index: 20 scientists 142–143 D-Index: 20 scientists 144–145 D-Index: 15 scientists 146–147 D-Index: 9 scientists 148–149 D-Index: 9 scientists 150–151 D-Index: 16 scientists 152–153 D-Index: 11 scientists 154–155 D-Index: 9 scientists 156–157 D-Index: 3 scientists 158 D-Index: 3 scientists 159+ D-Index: 98 scientists
40 D-Index 159+

This scientist: 53 D-Index — 28th percentile

28% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 159 D-Index or more.

Research.com Recognitions

  • 2020 - Fellow, National Academy of Inventors

Overview

Irwin M. Chaiken is affiliated with Drexel University in the United States. Their research primarily focuses on Medicine and Immunology and Microbiology, with significant contributions in related subfields such as Infectious Diseases, Virology, Molecular Biology, Immunology, and Radiology, Nuclear Medicine and Imaging.

The main topics of their work include HIV Research and Treatment, HIV/AIDS drug development and treatment, SARS-CoV-2 and COVID-19 Research, RNA Interference and Gene Delivery, Monoclonal and Polyclonal Antibodies Research, COVID-19 Clinical Research Studies, and Immune Cell Function and Interaction.

Irwin M. Chaiken has published extensively in several venues, with frequent publications in:

  • Frontiers in Immunology
  • Biochemistry
  • ACS Chemical Biology
  • The Journal of Immunology
  • bioRxiv (Cold Spring Harbor Laboratory)

Some selected recent papers include:

  • The Case for S2: The Potential Benefits of the S2 Subunit of the SARS-CoV-2 Spike Protein as an Immunogen in Fighting the COVID-19 Pandemic (2021), Frontiers in Immunology
  • The HIV-1 Env gp120 Inner Domain Shapes the Phe43 Cavity and the CD4 Binding Site (2020), mBio
  • Injectable Granular Hydrogels Enable Avidity-Controlled Biotherapeutic Delivery (2024), ACS Biomaterials Science & Engineering
  • Metastable HIV-1 Surface Protein Env Sensitizes Cell Membranes to Transformation and Poration by Dual-Acting Virucidal Entry Inhibitors (2020), Biochemistry
  • Irreversible Inactivation of SARS-CoV-2 by Lectin Engagement with Two Glycan Clusters on the Spike Protein (2023), Biochemistry

Frequent collaborators of Irwin M. Chaiken include:

  • Gabriela Canziani
  • Cameron F. Abrams
  • Charles G. Ang
  • Adel A. Rashad
  • Amos B. Smith

In 2020, Irwin M. Chaiken was recognized as a Fellow of the National Academy of Inventors.

Best Publications

  • HIV-1 evades antibody-mediated neutralization through conformational masking of receptor-binding sites

    Peter D. Kwong;Peter D. Kwong;Michael L. Doyle;Michael L. Doyle;David J. Casper;Claudia Cicala

  • Interpreting complex binding kinetics from optical biosensors: a comparison of analysis by linearization, the integrated rate equation, and numerical integration.

    T.A. Morton;D.G. Myszka;I.M. Chaiken

  • Nature of the charged-group effect on the stability of the C-peptide helix.

    Kevin R. Shoemaker;Peter S. Kim;David N. Brems;Susan Marqusee

  • Stable exposure of the coreceptor-binding site in a CD4-independent HIV-1 envelope protein

    Trevor L. Hoffman;Celia C. LaBranche;Wentao Zhang;Gabriella Canziani

  • Kinetic analysis of a protein antigen-antibody interaction limited by mass transport on an optical biosensor.

    David G. Myszka;Thomas A. Morton;Michael L. Doyle;Irwin M. Chaiken

  • Small-molecule inhibitors of HIV-1 entry block receptor-induced conformational changes in the viral envelope glycoproteins

    Zhihai Si;Navid Madani;Jason M. Cox;Jason J. Chruma

  • Analysis of macromolecular interactions using immobilized ligands.

    Irwin Chaiken;Sergio Rosé;Robert Karlsson

  • Semisynthetic peptides and proteins

    Irwin M. Chaiken

  • Click Chemistry in Peptide-Based Drug Design

    Huiyuan Li;Rachna Aneja;Irwin Chaiken

  • Controlled formation of model homo- and heterodimer coiled coil polypeptides

    Thomas J. Graddis;David G. Myszka;Irwin M. Chaiken

  • Binding Interactions of Human Interleukin 5 with Its Receptor α Subunit: LARGE SCALE PRODUCTION, STRUCTURAL, AND FUNCTIONAL STUDIES OF DROSOPHILA-EXPRESSED RECOMBINANT PROTEINS (∗)

    Kyung Johanson;Edward Appelbaum;Michael Doyle;Preston Hensley

  • Quantitative affinity chromatography. Determination of binding constants by elution with competitive inhibitors.

    Ben M. Dunn;Irwin M. Chaiken

  • Recombinant IL-5 antagonists useful in treatment of IL-5 mediated disorders

    Robert S. Ames;Edward Robert Appelbaum;Irwin M. Chaiken;Richard M. Cook

  • Conformational changes of gp120 in epitopes near the CCR5 binding site are induced by CD4 and a CD4 miniprotein mimetic.

    Wentao Zhang;Gabriela Canziani;Carmela Plugariu;Richard Wyatt

  • Anti-sense peptide recognition of sense peptides: direct quantitative characterization with the ribonuclease S-peptide system using analytical high-performance affinity chromatography.

    Yechiel Shai;Michael Flashner;Irwin M. Chaiken

  • Structure-based design, synthesis and validation of CD4-mimetic small molecule inhibitors of HIV-1 entry: conversion of a viral entry agonist to an antagonist

    Joel R. Courter;Navid Madani;Joseph Sodroski;Joseph Sodroski;Arne Schön

  • Evaluation of quantitative affinity chromatography by comparison with kinetic and equilibrium dialysis methods for the analysis of nucleotide binding to staphylococcal nuclease.

    Ben M. Dunn;Irwin M. Chaiken

  • Current trends in molecular recognition and bioseparation

    Chris Jones;Arun Patel;Skip Griffin;John Martin

  • Enhanced EGFR inhibition and distinct epitope recognition by EGFR antagonistic mAbs C225 and 425.

    Vishal Kamat;Joshua M. Donaldson;Csaba Kari;Marlene R.D. Quadros

  • Design and characterization of an intramolecular antiparallel coiled coil peptide.

    David G. Myszka;Irwin M. Chaiken

  • Kinetic and structural analysis of mutant CD4 receptors that are defective in HIV gp120 binding.

    Hao Wu;David G. Myszka;Susan W. Tendian;Christie G. Brouillette

  • Peptides 1982—Proceedings of the 17th European Peptide Symposium: Edited by K. Bláha and P. Malon̆, de Gruyter, Berlin, 1983. 846 pp. $134.00

    Irwin M. Chaiken

Frequent Co-Authors

Joseph Sodroski
Joseph Sodroski Harvard Medical School
David G. Myszka
David G. Myszka University of Utah
Amos B. Smith
Amos B. Smith University of Pennsylvania
Ernesto Freire
Ernesto Freire Johns Hopkins University
Thomas A. Morton
Thomas A. Morton University of Copenhagen
Wayne A. Hendrickson
Wayne A. Hendrickson Columbia University
Richard J. Cook
Richard J. Cook University of Waterloo
Richard T. Wyatt
Richard T. Wyatt Scripps Research Institute
Peter D. Kwong
Peter D. Kwong Columbia University Medical Center
Douglas B. Cines
Douglas B. Cines University of Pennsylvania

External Links

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Best Scientists Citing Irwin M. Chaiken

Joseph Sodroski

Joseph Sodroski

Harvard Medical School

Publications: 91

Peter D. Kwong

Peter D. Kwong

Columbia University Medical Center

Publications: 87

John R. Mascola

John R. Mascola

ModeX Therapeutics

Publications: 55

Barton F. Haynes

Barton F. Haynes

Duke University

Publications: 55

David C. Montefiori

David C. Montefiori

Duke University

Publications: 55

Andrés Finzi

Andrés Finzi

University of Montreal

Publications: 50

Dennis R. Burton

Dennis R. Burton

Scripps Research Institute

Publications: 47

Richard T. Wyatt

Richard T. Wyatt

Scripps Research Institute

Publications: 44

Amos B. Smith

Amos B. Smith

University of Pennsylvania

Publications: 36

Rogier W. Sanders

Rogier W. Sanders

University of Amsterdam

Publications: 33

David G. Myszka

David G. Myszka

University of Utah

Publications: 32

Robert W. Doms

Robert W. Doms

Children's Hospital of Philadelphia

Publications: 31

Susan Zolla-Pazner

Susan Zolla-Pazner

Icahn School of Medicine at Mount Sinai

Publications: 31

James A. Hoxie

James A. Hoxie

University of Pennsylvania

Publications: 29

George M. Shaw

George M. Shaw

University of Pennsylvania

Publications: 27

Tongqing Zhou

Tongqing Zhou

National Institutes of Health

Publications: 26

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