World's Best Scientists 2026 revealed!

D-Index & Metrics

Medicine

D-Index
78
Citations
18292
World Ranking
18184
National Ranking
733

Edoardo Spina publication distribution in Medicine in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Medicine in 2026. The highlighted bar marks where Edoardo Spina sits on this spectrum.

101–120 publications: 5 scientists 121–140 publications: 26 scientists 141–160 publications: 73 scientists 161–180 publications: 155 scientists 181–200 publications: 230 scientists 201–220 publications: 363 scientists 221–240 publications: 487 scientists 241–260 publications: 545 scientists 261–280 publications: 722 scientists 281–300 publications: 768 scientists 301–320 publications: 834 scientists 321–340 publications: 895 scientists 341–360 publications: 922 scientists 361–380 publications: 838 scientists 381–400 publications: 861 scientists 401–420 publications: 918 scientists 421–440 publications: 806 scientists 441–460 publications: 771 scientists 461–480 publications: 751 scientists 481–500 publications: 713 scientists 501–520 publications: 617 scientists 521–540 publications: 611 scientists 541–560 publications: 537 scientists 561–580 publications: 504 scientists 581–600 publications: 509 scientists 601–620 publications: 396 scientists 621–640 publications: 386 scientists 641–660 publications: 371 scientists 661–680 publications: 340 scientists 681–700 publications: 336 scientists 701–720 publications: 307 scientists 721–740 publications: 259 scientists 741–760 publications: 230 scientists 761–780 publications: 228 scientists 781–800 publications: 217 scientists 801–820 publications: 204 scientists 821–840 publications: 186 scientists 841–860 publications: 177 scientists 861–880 publications: 155 scientists 881–900 publications: 139 scientists 901–920 publications: 145 scientists 921–940 publications: 116 scientists 941–960 publications: 133 scientists 961–980 publications: 91 scientists 981–1,000 publications: 96 scientists 1,001–1,020 publications: 77 scientists 1,021–1,040 publications: 70 scientists 1,041–1,060 publications: 63 scientists 1,061–1,080 publications: 77 scientists 1,081–1,100 publications: 49 scientists 1,101–1,120 publications: 54 scientists 1,121–1,140 publications: 49 scientists 1,141–1,160 publications: 51 scientists 1,161–1,180 publications: 35 scientists 1,181–1,200 publications: 39 scientists 1,201–1,220 publications: 26 scientists 1,221–1,240 publications: 37 scientists 1,241–1,260 publications: 36 scientists 1,261–1,280 publications: 27 scientists 1,281–1,300 publications: 32 scientists 1,301–1,320 publications: 28 scientists 1,321–1,340 publications: 17 scientists 1,341–1,360 publications: 30 scientists 1,361–1,380 publications: 28 scientists 1,381–1,400 publications: 17 scientists 1,401–1,420 publications: 21 scientists 1,421–1,440 publications: 15 scientists 1,441–1,460 publications: 12 scientists 1,461–1,480 publications: 12 scientists 1,481–1,500 publications: 18 scientists 1,501–1,520 publications: 14 scientists 1,521–1,540 publications: 17 scientists 1,541–1,560 publications: 15 scientists 1,561–1,580 publications: 6 scientists 1,581–1,600 publications: 2 scientists 1,601–1,620 publications: 12 scientists 1,621–1,640 publications: 11 scientists 1,641–1,660 publications: 8 scientists 1,661–1,680 publications: 5 scientists 1,681–1,700 publications: 5 scientists 1,701–1,720 publications: 10 scientists 1,721–1,740 publications: 12 scientists 1,741–1,760 publications: 14 scientists 1,761–1,780 publications: 6 scientists 1,781–1,795 publications: 5 scientists 1,796+ publications: 100 scientists
101 publications 1,796+

This scientist: 330 publications — 23rd percentile

23% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,796 publications or more.

Edoardo Spina D-index placement in Medicine in 2026

The chart shows the D-index (discipline H-index) distribution of Medicine scientists ranked by Research.com in 2026. The highlighted bar marks where Edoardo Spina sits on this spectrum.

70–71 D-Index: 226 scientists 72–73 D-Index: 391 scientists 74–75 D-Index: 574 scientists 76–77 D-Index: 730 scientists 78–79 D-Index: 891 scientists 80–81 D-Index: 972 scientists 82–83 D-Index: 1,027 scientists 84–85 D-Index: 1,003 scientists 86–87 D-Index: 960 scientists 88–89 D-Index: 970 scientists 90–91 D-Index: 922 scientists 92–93 D-Index: 839 scientists 94–95 D-Index: 808 scientists 96–97 D-Index: 779 scientists 98–99 D-Index: 668 scientists 100–101 D-Index: 611 scientists 102–103 D-Index: 630 scientists 104–105 D-Index: 513 scientists 106–107 D-Index: 541 scientists 108–109 D-Index: 445 scientists 110–111 D-Index: 429 scientists 112–113 D-Index: 400 scientists 114–115 D-Index: 393 scientists 116–117 D-Index: 318 scientists 118–119 D-Index: 302 scientists 120–121 D-Index: 287 scientists 122–123 D-Index: 255 scientists 124–125 D-Index: 256 scientists 126–127 D-Index: 252 scientists 128–129 D-Index: 230 scientists 130–131 D-Index: 179 scientists 132–133 D-Index: 168 scientists 134–135 D-Index: 163 scientists 136–137 D-Index: 159 scientists 138–139 D-Index: 134 scientists 140–141 D-Index: 134 scientists 142–143 D-Index: 118 scientists 144–145 D-Index: 109 scientists 146–147 D-Index: 106 scientists 148–149 D-Index: 74 scientists 150–151 D-Index: 79 scientists 152–153 D-Index: 80 scientists 154–155 D-Index: 87 scientists 156–157 D-Index: 57 scientists 158–159 D-Index: 74 scientists 160–161 D-Index: 69 scientists 162–163 D-Index: 60 scientists 164–165 D-Index: 53 scientists 166–167 D-Index: 39 scientists 168–169 D-Index: 42 scientists 170–171 D-Index: 32 scientists 172–173 D-Index: 39 scientists 174–175 D-Index: 40 scientists 176–177 D-Index: 28 scientists 178–179 D-Index: 19 scientists 180–181 D-Index: 23 scientists 182–183 D-Index: 31 scientists 184–185 D-Index: 18 scientists 186–187 D-Index: 20 scientists 188–189 D-Index: 22 scientists 190–191 D-Index: 13 scientists 192–193 D-Index: 21 scientists 194–195 D-Index: 12 scientists 196–197 D-Index: 12 scientists 198–199 D-Index: 14 scientists 200–201 D-Index: 15 scientists 202–203 D-Index: 13 scientists 204–205 D-Index: 10 scientists 206–207 D-Index: 8 scientists 208–209 D-Index: 4 scientists 210–211 D-Index: 12 scientists 212–213 D-Index: 11 scientists 214–215 D-Index: 10 scientists 216 D-Index: 4 scientists 217+ D-Index: 98 scientists
70 D-Index 217+

This scientist: 78 D-Index — 12th percentile

12% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 217 D-Index or more.

Overview

Edoardo Spina is affiliated with the University of Messina in Italy and has contributed extensively to the field of medicine, with a focus on psychiatry, pharmacology, pediatrics, oncology, and surgery. Their research emphasizes several key areas including schizophrenia research and treatment, treatment of major depression, pharmaceutical studies and practices, bipolar disorder and treatment, pharmacovigilance and adverse drug reactions, biosimilars and bioanalytical methods, and epilepsy research and treatment.

Spina has published papers in a variety of academic journals with notable recurring appearances in such venues as:

  • Pharmaceuticals
  • CNS & Neurological Disorders - Drug Targets
  • Neuroscience Applied
  • Expert Opinion on Drug Metabolism & Toxicology
  • Frontiers in Pharmacology

Recent research publications by Spina include:

  • "An International Adult Guideline for Making Clozapine Titration Safer by Using Six Ancestry-Based Personalized Dosing Titrations, CRP, and Clozapine Levels" (2021), published in Pharmacopsychiatry
  • "COVID-19 Vaccination in Pregnancy, Paediatrics, Immunocompromised Patients, and Persons with History of Allergy or Prior SARS-CoV-2 Infection: Overview of Current Recommendations and Pre- and Post-Marketing Evidence for Vaccine Efficacy and Safety" (2021), published in Drug Safety
  • "Safety profiles of biologic agents for inflammatory bowel diseases: a prospective pharmacovigilance study in Southern Italy" (2020), published in Current Medical Research and Opinion
  • "An update on the complex relationship between clozapine and pneumonia" (2021), published in Expert Review of Clinical Pharmacology
  • "A Narrative Review on Efficacy and Safety of Proton Pump Inhibitors in Children" (2022), published in Frontiers in Pharmacology

Frequent co-authors collaborating with Spina include:

  • María Antonietta Barbieri
  • Giuseppe Cicala
  • Paola Maria Cutroneo
  • José de León
  • Georgios Schoretsanitis

Spina's work spans multiple subfields of medicine, prominently including:

  • Psychiatry and Mental health
  • Pharmacology
  • Pediatrics, Perinatology and Child Health
  • Oncology
  • Surgery

The scientist's research also addresses topics of clinical and pharmaceutical relevance, focusing particularly on:

  • Schizophrenia research and treatment
  • Treatment of Major Depression
  • Pharmaceutical studies and practices
  • Bipolar Disorder and Treatment
  • Pharmacovigilance and Adverse Drug Reactions
  • Biosimilars and Bioanalytical Methods
  • Epilepsy research and treatment

Best Publications

  • CYP2D6 and CYP2C19 genotype-based dose recommendations for antidepressants: a first step towards subpopulation-specific dosages.

    J Kirchheiner;K Brosen;Marja-Liisa Dahl;LF Gram

  • Clinically relevant pharmacokinetic drug interactions with second-generation antidepressants: An update

    Edoardo Spina;Vincenza Santoro;Concetta D'Arrigo

  • CLINICALLY SIGNIFICANT PHARMACOKINETIC DRUG INTERACTIONS WITH CARBAMAZEPINE: AN UPDATE

    Edoardo Spina;Franco Pisani;Emilio Perucca

  • Influence of CYP2C9 and CYP2C19 genetic polymorphisms on warfarin maintenance dose and metabolic clearance

    Maria Gabriella Scordo;Maria Gabriella Scordo;Maria Gabriella Scordo;Vittorio Pengo;Vittorio Pengo;Vittorio Pengo;Edoardo Spina;Edoardo Spina;Edoardo Spina;Marja Liisa Dahl;Marja Liisa Dahl;Marja Liisa Dahl

  • Metabolic drug interactions with newer antipsychotics: a comparative review.

    Edoardo Spina;Jose de Leon

  • Antiepileptic drugs: indications other than epilepsy

    Edoardo Spina;Giulio Perugi

  • Genetic polymorphism of cytochrome P450 2C9 in a Caucasian and a black African population.

    Maria Gabriella Scordo;Maria Gabriella Scordo;Eleni Aklillu;Umit Yasar;Marja-Liisa Dahl

  • Allele and genotype frequencies of CYP2C9, CYP2C19 and CYP2D6 in an Italian population.

    Maria Gabriella Scordo;Achille P Caputi;Concetta D'Arrigo;Giuseppina Fava

  • Quetiapine and clozapine in parkinsonian patients with dopaminergic psychosis

    Letterio Morgante;Antonio Epifanio;Edoardo Spina;Mario Zappia

  • Cytochrome P450 2D6 genotype and steady state plasma levels of risperidone and 9-hydroxyrisperidone.

    Maria Gabriella Scordo;Edoardo Spina;Gabriella Facciolà;Angela Avenoso

  • Relationship between plasma concentrations of clozapine and norclozapine and therapeutic response in patients with schizophrenia resistant to conventional neuroleptics

    Edoardo Spina;Angela Avenoso;Gabriella Facciolà;Maria G. Scordo

  • Different enantioselective 9-hydroxylation of risperidone by the two human CYP2D6 and CYP3A4 enzymes.

    Norio Yasui-Furukori;Mats Hidestrand;Edoardo Spina;Gabriella Facciolá

  • Clinically significant drug interactions with newer antidepressants.

    Edoardo Spina;Gianluca Trifirò;Filippo Caraci

  • Metabolic drug interactions with new psychotropic agents.

    Edoardo Spina;Maria Gabriella Scordo;Concetta D'Arrigo

  • Clinically significant drug interactions with antidepressants in the elderly.

    Edoardo Spina;Maria Gabriella Scordo

  • Effect of fluvoxamine on the pharmacokinetics of imipramine and desipramine in healthy subjects.

    E. Spina;A. M. Pollicino;A. Avenoso;G. M. Campo

  • Plasma Concentrations of Risperidone and 9-Hydroxyrisperidone: Effect of Comedication With Carbamazepine or Valproate

    Edoardo Spina;Angela Avenoso;Gabriella Facciolà;Monica Salemi

  • The economic burden of preventable adverse drug reactions: a systematic review of observational studies

    D Formica;J Sultana;P M Cutroneo;S Lucchesi

  • Clinical applications of CYP genotyping in psychiatry.

    Edoardo Spina;Jose de Leon;Jose de Leon;Jose de Leon

  • Inhibition of risperidone metabolism by fluoxetine in patients with schizophrenia: a clinically relevant pharmacokinetic drug interaction.

    Edoardo Spina;Angela Avenoso;Maria Gabriella Scordo;Maria Ancione

Frequent Co-Authors

Jose de Leon
Jose de Leon University of Kentucky
Achille P. Caputi
Achille P. Caputi University of Messina
Emilio Perucca
Emilio Perucca University of Pavia
Marja-Liisa Dahl
Marja-Liisa Dahl Karolinska University Hospital
Alessandro Serretti
Alessandro Serretti Kore University of Enna
Placido Bramanti
Placido Bramanti University of Messina
Fortunato Battaglia
Fortunato Battaglia Seton Hall University
Edoardo Ferlazzo
Edoardo Ferlazzo Magna Graecia University
Siegfried Kasper
Siegfried Kasper Medical University of Vienna
Umberto Aguglia
Umberto Aguglia Magna Graecia University

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