World's Best Scientists 2026 revealed!

D-Index & Metrics

Medicine

D-Index
96
Citations
32581
World Ranking
9699
National Ranking
537

Overview

Ivar Roots is affiliated with Charité - University Medicine Berlin in Germany. Their academic profile reflects an active engagement in research related to their affiliation, contributing to the scientific community through their work conducted at this institution.

No specific recent papers, co-authors, or publication venues have been listed, which suggests that available public records do not currently include detailed information about their specific research outputs or collaborative networks.

Similarly, there are no recorded book publications, main fields of study, or subfields of study attributed to Ivar Roots. The absence of such details limits the ability to define precise areas of scientific inquiry or thematic focuses within their academic work.

The same applies to the main topics covered in their research. Without listed topics or thematic categorizations, it is not possible to specify the particular issues or disciplines they have addressed in their scholarly activities.

There are no awards or recognitions documented for Ivar Roots, which indicates that either such honors have not been publicly recorded or have not been conferred.

Best Publications

  • Functional polymorphisms of the human multidrug-resistance gene: Multiple sequence variations and correlation of one allele with P-glycoprotein expression and activity in vivo

    S. Hoffmeyer;O. Burk;O. von Richter;H. P. Arnold

  • Cytochrome P450 2D6 variants in a Caucasian population: allele frequencies and phenotypic consequences.

    C Sachse;J Brockmöller;S Bauer;I Roots

  • Functional significance of a C-->A polymorphism in intron 1 of the cytochrome P450 CYP1A2 gene tested with caffeine

    Christoph Sachse;Jürgen Brockmöller;Steffen Bauer;Ivar Roots

  • Pharmacogenetics of antidepressants and antipsychotics: the contribution of allelic variations to the phenotype of drug response

    Kirchheiner J;Nickchen K;Bauer M;Wong Ml

  • Frequency of single nucleotide polymorphisms in the P-glycoprotein drug transporter MDR1 gene in white subjects.

    Ingolf Cascorbi;Thomas Gerloff;Andreas Johne;Christian Meisel

  • Pharmacokinetic interaction of digoxin with an herbal extract from St John's wort (Hypericum perforatum)

    Andreas Johne;Jörgen Brockmöller;Steffen Bauer;Agathe Maurer

  • CYP2D6 and CYP2C19 genotype-based dose recommendations for antidepressants: a first step towards subpopulation-specific dosages.

    J Kirchheiner;K Brosen;Marja-Liisa Dahl;LF Gram

  • Pharmacokinetics of codeine and its metabolite morphine in ultra-rapid metabolizers due to CYP2D6 duplication.

    J Kirchheiner;H Schmidt;M Tzvetkov;J-T H A Keulen

  • Combined Analysis of Inherited Polymorphisms in Arylamine N-Acetyltransferase 2, Glutathione S-Transferases M1 and T1, Microsomal Epoxide Hydrolase, and Cytochrome P450 Enzymes as Modulators of Bladder Cancer Risk

    Jürgen Brockmöller;Ingolf Cascorbi;Reinhold Kerb;Ivar Roots

  • A C4887A polymorphism in exon 7 of human CYP1A1: population frequency, mutation linkages, and impact on lung cancer susceptibility.

    Ingolf Cascorbi;Jürgen Brockmöller;Ivar Roots

  • Arylamine N-acetyltransferase (NAT2) mutations and their allelic linkage in unrelated Caucasian individuals: correlation with phenotypic activity.

    I Cascorbi;N Drakoulis;J Brockmöller;A Maurer

  • Association between the C3435T MDR1 gene polymorphism and susceptibility for ulcerative colitis

    Matthias Schwab;Elke Schaeffeler;Claudia Marx;Martin F. Fromm

  • Modulation of steady-state kinetics of digoxin by haplotypes of the P-glycoprotein MDR1 gene.

    Andreas Johne;Karla Köpke;Thomas Gerloff;Ingrid Mai

  • Polymorphisms of drug-metabolizing enzymes CYP2C9, CYP2C19, CYP2D6, CYP1A1, NAT2 and of P-glycoprotein in a Russian population

    Elena A. Gaikovitch;Ingolf Cascorbi;Przemyslaw M. Mrozikiewicz;Jürgen Brockmöller

  • Reduced nicotinamide adenine dinucleotide phosphate (NADPH)-dependent formation and breakdown of hydrogen peroxide during mixed function oxidation reactions in liver microsomes

    A G Hildebraunt;I Roots

  • Critical evaluation of the effect of valerian extract on sleep structure and sleep quality.

    F. Donath;S. Quispe;K. Diefenbach;A. Maurer

  • Frequency of cytochrome P450 CYP2C9 variants in a Turkish population and functional relevance for phenytoin

    A Sükrü Aynacioglu;A Sükrü Aynacioglu;Jürgen Brockmöller;Steffen Bauer;Christoph Sachse

  • Evidence for Inverse Effects of OATP-C (SLC21A6) *5 and *1b Haplotypes on Pravastatin Kinetics

    Jessica Mwinyi;Andreas Johne;Steffen Bauer;Ivar Roots

  • Patient-Tailored Antiemetic Treatment With 5-Hydroxytryptamine Type 3 Receptor Antagonists According to Cytochrome P-450 2D6 Genotypes

    Rolf Kaiser;Orhan Sezer;Anja Papies;Steffen Bauer

  • Hypericin and Pseudohypericin: Pharmacokinetics and Effects on Photosensitivity in Humans

    J. Brockmöller;T. Reum;S. Bauer;R. Kerb

Frequent Co-Authors

Jürgen Brockmöller
Jürgen Brockmöller University of Göttingen
Ingolf Cascorbi
Ingolf Cascorbi Kiel University
Ulrich Brinkmann
Ulrich Brinkmann Roche (Switzerland)
Klemens Budde
Klemens Budde Charité - University Medicine Berlin
Michel Eichelbaum
Michel Eichelbaum University of Tübingen
Matthias Schwab
Matthias Schwab University of Tübingen
Helmut Bartsch
Helmut Bartsch German Cancer Research Center
Orhan Sezer
Orhan Sezer Charité - University Medicine Berlin
Jörn Lötsch
Jörn Lötsch Goethe University Frankfurt
Gerd Walz
Gerd Walz University of Freiburg

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