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D-Index & Metrics

Biology and Biochemistry

D-Index
50
Citations
9889
World Ranking
17568
National Ranking
1270

Overview

Souichi Adachi is affiliated with Shiga Prefectural General Hospital in Japan, contributing extensively to medical research in hematology and related fields. Their primary fields of study include Medicine and Biochemistry, Genetics and Molecular Biology, with a significant focus on subfields such as Hematology, Molecular Biology, Public Health, Environmental and Occupational Health, Genetics, and Oncology.

The scientist's work spans various main research topics, notably Acute Myeloid Leukemia Research, Acute Lymphoblastic Leukemia research, Hematopoietic Stem Cell Transplantation, Histone Deacetylase Inhibitors Research, Chronic Myeloid Leukemia Treatments, CAR-T cell therapy research, and Protein Degradation and Inhibitors.

Souichi Adachi has published a notable number of papers in several prominent journals. Their frequent publication venues include:

  • Blood
  • Pediatric Blood & Cancer
  • Leukemia
  • Haematologica
  • Cancer Science

Significant recent publications include:

  • Clinical significance of RAS pathway alterations in pediatric acute myeloid leukemia, 2021, Haematologica
  • Fusion partner-specific mutation profiles and KRAS mutations as adverse prognostic factors in MLL-rearranged AML, 2020, Blood Advances
  • Predictive factors for the development of leukemia in patients with transient abnormal myelopoiesis and Down syndrome, 2021, Leukemia
  • Discontinuation of tyrosine kinase inhibitors in pediatric chronic myeloid leukemia, 2022, Pediatric Blood & Cancer
  • The outcomes of relapsed acute myeloid leukemia in children: Results from the Japanese Pediatric Leukemia/Lymphoma Study Group AML-05R study, 2020, Pediatric Blood & Cancer

The scientist collaborates frequently with several researchers, including:

  • Junko Takita
  • Takashi Taga
  • Hidefumi Hiramatsu
  • Daisuke Tomizawa
  • Katsutsugu Umeda

Best Publications

  • Diagnosis and management of acute myeloid leukemia in children and adolescents: recommendations from an international expert panel.

    Ursula Creutzig;Marry M. van den Heuvel-Eibrink;Brenda Gibson;Michael N. Dworzak

  • The landscape of somatic mutations in Down syndrome-related myeloid disorders

    Kenichi Yoshida;Tsutomu Toki;Yusuke Okuno;Rika Kanezaki

  • Collaborative Efforts Driving Progress in Pediatric Acute Myeloid Leukemia

    C. Michel Zwaan;Edward A. Kolb;Dirk Reinhardt;Jonas Abrahamsson

  • An Inv(16)(p13.3q24.3)-encoded CBFA2T3-GLIS2 fusion protein defines an aggressive subtype of pediatric acute megakaryoblastic leukemia.

    Tanja A. Gruber;Amanda Larson Gedman;Jinghui Zhang;Cary S. Koss

  • Feasibility of HLA-haploidentical hematopoietic stem cell transplantation between noninherited maternal antigen (NIMA)-mismatched family members linked with long-term fetomaternal microchimerism

    Tatsuo Ichinohe;Takashi Uchiyama;Chihiro Shimazaki;Keitaro Matsuo

  • Long-term efficacy of hematopoietic stem cell transplantation on brain involvement in patients with mucopolysaccharidosis type II: a nationwide survey in Japan.

    Akemi Tanaka;Torayuki Okuyama;Yasuyuki Suzuki;Norio Sakai

  • Calcineurin Pathway Is Required for Endothelin-1–Mediated Protection Against Oxidant Stress–Induced Apoptosis in Cardiac Myocytes

    Tsuyoshi Kakita;Koji Hasegawa;Eri Iwai-Kanai;Souichi Adachi

  • Disease-associated CIAS1 mutations induce monocyte death, revealing low-level mosaicism in mutation-negative cryopyrin-associated periodic syndrome patients

    Megumu Saito;Ryuta Nishikomori;Naotomo Kambe;Naotomo Kambe;Akihiro Fujisawa

  • Disease-associated mutations in CIAS1 induce cathepsin B-dependent rapid cell death of human THP-1 monocytic cells.

    Akihiro Fujisawa;Naotomo Kambe;Megumu Saito;Ryuta Nishikomori

  • Uric acid induces NADPH oxidase-independent neutrophil extracellular trap formation.

    Yasuyuki Arai;Yoko Nishinaka;Toshiyuki Arai;Makiko Morita

  • Singlet oxygen is essential for neutrophil extracellular trap formation.

    Yoko Nishinaka;Toshiyuki Arai;Souichi Adachi;Akifumi Takaori-Kondo

  • A novel mechanism for imatinib mesylate-induced cell death of BCR-ABL-positive human leukemic cells: caspase-independent, necrosis-like programmed cell death mediated by serine protease activity.

    Masayuki Okada;Souichi Adachi;Tsuyoshi Imai;Ken-ichiro Watanabe

  • NUP98-NSD1 gene fusion and its related gene expression signature are strongly associated with a poor prognosis in pediatric acute myeloid leukemia.

    Norio Shiba;Hitoshi Ichikawa;Tomohiko Taki;Myoung Ja Park

  • Genetic regulation of the RUNX transcription factor family has antitumor effects

    Ken Morita;Kensho Suzuki;Shintaro Maeda;Akihiko Matsuo

  • Down syndrome and GATA1 mutations in transient abnormal myeloproliferative disorder: mutation classes correlate with progression to myeloid leukemia

    Rika Kanezaki;Tsutomu Toki;Kiminori Terui;Gang Xu

  • Induction of autophagy in malignant rhabdoid tumor cells by the histone deacetylase inhibitor FK228 through AIF translocation.

    Motonobu Watanabe;Souichi Adachi;Hiroshi Matsubara;Tsuyoshi Imai

  • Constitutive SIRT1 overexpression impairs mitochondria and reduces cardiac function in mice.

    Tsuneaki Kawashima;Yasutaka Inuzuka;Junji Okuda;Takao Kato

  • Acute myeloid leukemia in children: Current status and future directions.

    Takashi Taga;Daisuke Tomizawa;Hiroyuki Takahashi;Souichi Adachi

  • Activation of Lectin-Like Oxidized Low-Density Lipoprotein Receptor-1 Induces Apoptosis in Cultured Neonatal Rat Cardiac Myocytes

    Eri Iwai-Kanai;Koji Hasegawa;Tatsuya Sawamura;Masatoshi Fujita

  • t(6;9)(p22;q34)/DEK-NUP214-rearranged pediatric myeloid leukemia: an international study of 62 patients

    Julie Damgaard Sandahl;Eva A. Coenen;Erik Forestier;Jochen Harbott

Frequent Co-Authors

Yasuhide Hayashi
Yasuhide Hayashi Gunma Children's Medical Center
Tatsutoshi Nakahata
Tatsutoshi Nakahata Kyoto University
Seishi Ogawa
Seishi Ogawa Kyoto University
Toshio Heike
Toshio Heike Kyoto University
Tomohiko Taki
Tomohiko Taki Kyorin University
Yuichi Shiraishi
Yuichi Shiraishi University of Tokyo
Satoru Miyano
Satoru Miyano Tokyo Medical and Dental University
Etsuro Ito
Etsuro Ito Hirosaki University
Hiroshi Matsubara
Hiroshi Matsubara Osaka Metropolitan University
Shuki Mizutani
Shuki Mizutani Tokyo Medical and Dental University

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