His primary areas of study are Cell biology, Nuclear protein, Nuclear transport, Nuclear lamina and Biochemistry. His work on Lamin and Importin as part of general Cell biology study is frequently connected to Nucleoplasm and RNA polymerase II, therefore bridging the gap between diverse disciplines of science and establishing a new relationship between them. The Nuclear protein study combines topics in areas such as Plasma protein binding and NLS.
Nuclear transport is a subfield of Cell nucleus that Stephen A. Adam studies. When carried out as part of a general Cell nucleus research project, his work on Importin-alpha is frequently linked to work in Cytosol, therefore connecting diverse disciplines of study. His work deals with themes such as Chromatin, Reactive oxygen species, Gene silencing and Euchromatin, which intersect with Nuclear lamina.
The scientist’s investigation covers issues in Cell biology, Nuclear lamina, Lamin, Nuclear transport and Nuclear pore. Stephen A. Adam focuses mostly in the field of Cell biology, narrowing it down to matters related to Intermediate filament and, in some cases, Keratin. His Nuclear lamina study integrates concerns from other disciplines, such as Molecular biology, Progerin, Transcription and DNA repair.
His Nuclear transport research incorporates elements of Nuclear protein and Nuclear localization sequence. Nuclear protein is a subfield of Biochemistry that he tackles. His Nuclear pore research is multidisciplinary, incorporating perspectives in Proteome, Biophysics and Nucleoporin.
Stephen A. Adam mostly deals with Lamin, Nuclear lamina, Cell biology, Chromatin and Nuclear pore. The study of Lamin is intertwined with the study of Gene expression in a number of ways. His Nuclear lamina research includes themes of RNA, LINC complex, Knockout mouse and Transcription.
His Cell biology study incorporates themes from Cell and Intermediate filament. His biological study spans a wide range of topics, including Nucleoporin, Gene knockdown and Gene isoform. Cell nucleus is a subfield of Cytoplasm that Stephen A. Adam explores.
Cell biology, Lamin, Vimentin, Intermediate filament and Chromatin are his primary areas of study. His study in Cell biology focuses on Cell nucleus in particular. The concepts of his Cell nucleus study are interwoven with issues in Progeria and Intracellular.
Stephen A. Adam combines subjects such as Housekeeping gene, Gene expression, Genome, Genomic organization and Nuclear lamina with his study of Lamin. His research in Nuclear lamina intersects with topics in Histone H2A, Chromatin remodeling, Histone H1 and Chromosome. His Intermediate filament research integrates issues from Kinesin, Biophysics, Actin cytoskeleton and Keratin.
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Nuclear protein import in permeabilized mammalian cells requires soluble cytoplasmic factors.
Stephen A. Adam;Rachel Sterne Marr;Larry Gerace.
Journal of Cell Biology (1990)
Mutant nuclear lamin A leads to progressive alterations of epigenetic control in premature aging
Dale K. Shumaker;Thomas Dechat;Alexander Kohlmaier;Alexander Kohlmaier;Stephen A. Adam.
Proceedings of the National Academy of Sciences of the United States of America (2006)
Importin α: A multipurpose nuclear-transport receptor
David S. Goldfarb;Anita H. Corbett;D. Adam Mason;Michelle T. Harreman.
Trends in Cell Biology (2004)
mRNA polyadenylate-binding protein: gene isolation and sequencing and identification of a ribonucleoprotein consensus sequence.
S A Adam;T Nakagawa;M S Swanson;T K Woodruff.
Molecular and Cellular Biology (1986)
The A- and B-type nuclear lamin networks: microdomains involved in chromatin organization and transcription
Takeshi Shimi;Katrin Pfleghaar;Katrin Pfleghaar;Shin Ichiro Kojima;Chan Gi Pack.
Genes & Development (2008)
Cytosolic proteins that specifically bind nuclear location signals are receptors for nuclear import.
Stephen A. Adam;Stephen A. Adam;Larry Geracet.
Cell (1991)
Autophagy mediates degradation of nuclear lamina
Zhixun Dou;Caiyue Xu;Greg Donahue;Takeshi Shimi.
Nature (2015)
Physical change in cytoplasmic messenger ribonucleoproteins in cells treated with inhibitors of mRNA transcription.
G Dreyfuss;S A Adam;Y D Choi.
Molecular and Cellular Biology (1984)
Identification of cytosolic factors required for nuclear location sequence-mediated binding to the nuclear envelope
Ermoné J.H. Adam;Stephen A Adam.
Journal of Cell Biology (1994)
Role of Importin-β in Coupling Ran to Downstream Targets in Microtubule Assembly
Christiane Wiese;Andrew Wilde;Mary Shannon Moore;Stephen A. Adam.
Science (2001)
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