D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 54 Citations 13,843 81 World Ranking 10888 National Ranking 4705

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Gene expression
  • Cell nucleus

His primary areas of study are Cell biology, Nuclear protein, Nuclear transport, Nuclear lamina and Biochemistry. His work on Lamin and Importin as part of general Cell biology study is frequently connected to Nucleoplasm and RNA polymerase II, therefore bridging the gap between diverse disciplines of science and establishing a new relationship between them. The Nuclear protein study combines topics in areas such as Plasma protein binding and NLS.

Nuclear transport is a subfield of Cell nucleus that Stephen A. Adam studies. When carried out as part of a general Cell nucleus research project, his work on Importin-alpha is frequently linked to work in Cytosol, therefore connecting diverse disciplines of study. His work deals with themes such as Chromatin, Reactive oxygen species, Gene silencing and Euchromatin, which intersect with Nuclear lamina.

His most cited work include:

  • Nuclear protein import in permeabilized mammalian cells requires soluble cytoplasmic factors. (802 citations)
  • Mutant nuclear lamin A leads to progressive alterations of epigenetic control in premature aging (558 citations)
  • Importin α: A multipurpose nuclear-transport receptor (511 citations)

What are the main themes of his work throughout his whole career to date?

The scientist’s investigation covers issues in Cell biology, Nuclear lamina, Lamin, Nuclear transport and Nuclear pore. Stephen A. Adam focuses mostly in the field of Cell biology, narrowing it down to matters related to Intermediate filament and, in some cases, Keratin. His Nuclear lamina study integrates concerns from other disciplines, such as Molecular biology, Progerin, Transcription and DNA repair.

His Nuclear transport research incorporates elements of Nuclear protein and Nuclear localization sequence. Nuclear protein is a subfield of Biochemistry that he tackles. His Nuclear pore research is multidisciplinary, incorporating perspectives in Proteome, Biophysics and Nucleoporin.

He most often published in these fields:

  • Cell biology (58.43%)
  • Nuclear lamina (44.94%)
  • Lamin (41.57%)

What were the highlights of his more recent work (between 2016-2021)?

  • Lamin (41.57%)
  • Nuclear lamina (44.94%)
  • Cell biology (58.43%)

In recent papers he was focusing on the following fields of study:

Stephen A. Adam mostly deals with Lamin, Nuclear lamina, Cell biology, Chromatin and Nuclear pore. The study of Lamin is intertwined with the study of Gene expression in a number of ways. His Nuclear lamina research includes themes of RNA, LINC complex, Knockout mouse and Transcription.

His Cell biology study incorporates themes from Cell and Intermediate filament. His biological study spans a wide range of topics, including Nucleoporin, Gene knockdown and Gene isoform. Cell nucleus is a subfield of Cytoplasm that Stephen A. Adam explores.

Between 2016 and 2021, his most popular works were:

  • Chromatin and lamin A determine two different mechanical response regimes of the cell nucleus (184 citations)
  • Mapping 3D genome organization relative to nuclear compartments using TSA-Seq as a cytological ruler (116 citations)
  • Chromatin histone modifications and rigidity affect nuclear morphology independent of lamins (107 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Gene expression
  • Cell nucleus

Cell biology, Lamin, Vimentin, Intermediate filament and Chromatin are his primary areas of study. His study in Cell biology focuses on Cell nucleus in particular. The concepts of his Cell nucleus study are interwoven with issues in Progeria and Intracellular.

Stephen A. Adam combines subjects such as Housekeeping gene, Gene expression, Genome, Genomic organization and Nuclear lamina with his study of Lamin. His research in Nuclear lamina intersects with topics in Histone H2A, Chromatin remodeling, Histone H1 and Chromosome. His Intermediate filament research integrates issues from Kinesin, Biophysics, Actin cytoskeleton and Keratin.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Nuclear protein import in permeabilized mammalian cells requires soluble cytoplasmic factors.

Stephen A. Adam;Rachel Sterne Marr;Larry Gerace.
Journal of Cell Biology (1990)

1017 Citations

Mutant nuclear lamin A leads to progressive alterations of epigenetic control in premature aging

Dale K. Shumaker;Thomas Dechat;Alexander Kohlmaier;Alexander Kohlmaier;Stephen A. Adam.
Proceedings of the National Academy of Sciences of the United States of America (2006)

771 Citations

Importin α: A multipurpose nuclear-transport receptor

David S. Goldfarb;Anita H. Corbett;D. Adam Mason;Michelle T. Harreman.
Trends in Cell Biology (2004)

724 Citations

mRNA polyadenylate-binding protein: gene isolation and sequencing and identification of a ribonucleoprotein consensus sequence.

S A Adam;T Nakagawa;M S Swanson;T K Woodruff.
Molecular and Cellular Biology (1986)

580 Citations

The A- and B-type nuclear lamin networks: microdomains involved in chromatin organization and transcription

Takeshi Shimi;Katrin Pfleghaar;Katrin Pfleghaar;Shin Ichiro Kojima;Chan Gi Pack.
Genes & Development (2008)

514 Citations

Cytosolic proteins that specifically bind nuclear location signals are receptors for nuclear import.

Stephen A. Adam;Stephen A. Adam;Larry Geracet.
Cell (1991)

490 Citations

Autophagy mediates degradation of nuclear lamina

Zhixun Dou;Caiyue Xu;Greg Donahue;Takeshi Shimi.
Nature (2015)

485 Citations

Physical change in cytoplasmic messenger ribonucleoproteins in cells treated with inhibitors of mRNA transcription.

G Dreyfuss;S A Adam;Y D Choi.
Molecular and Cellular Biology (1984)

397 Citations

Identification of cytosolic factors required for nuclear location sequence-mediated binding to the nuclear envelope

Ermoné J.H. Adam;Stephen A Adam.
Journal of Cell Biology (1994)

380 Citations

Role of Importin-β in Coupling Ran to Downstream Targets in Microtubule Assembly

Christiane Wiese;Andrew Wilde;Mary Shannon Moore;Stephen A. Adam.
Science (2001)

379 Citations

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