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Biology and Biochemistry

D-Index
54
Citations
14984
World Ranking
15412
National Ranking
1211

Overview

Lothar Schermelleh is affiliated with the University of Oxford in the United Kingdom. Their research contributions span the fields of Biochemistry, Genetics, and Molecular Biology, with a particular focus on Molecular Biology, Biophysics, Plant Science, Structural Biology, and Biomedical Engineering.

The scientist's work covers several main topics, including:

  • Advanced Fluorescence Microscopy Techniques
  • Genomics and Chromatin Dynamics
  • Cell Image Analysis Techniques
  • Advanced Electron Microscopy Techniques and Applications
  • RNA Research and Splicing
  • Molecular Biology Techniques and Applications
  • Optical Coherence Tomography Applications

Among the recent papers involving Lothar Schermelleh are the following:

  • "Chromatin arranges in chains of mesoscale domains with nanoscale functional topography independent of cohesin," 2020, published in Science Advances
  • "Whole-body integration of gene expression and single-cell morphology," 2021, published in Cell
  • "Super-resolution microscopy: a brief history and new avenues," 2022, published in Philosophical Transactions of the Royal Society A Mathematical Physical and Engineering Sciences
  • "Structured illumination microscopy with noise-controlled image reconstructions," 2021, published in Nature Methods
  • "Time-resolved structured illumination microscopy reveals key principles of Xist RNA spreading," 2021, published in Science

Frequent coauthors contributing to these works alongside Lothar Schermelleh include:

  • Roel Oldenkamp
  • David Miguel Susano Pinto
  • Kirti Prakash
  • Carlas Smith
  • Kim Nasmyth

Schermelleh's publications have been frequently featured in venues such as:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Cell
  • Science
  • Journal of Visualized Experiments
  • OPAL (Open@LaTrobe) (La Trobe University)

Best Publications

  • A guide to super-resolution fluorescence microscopy

    Lothar Schermelleh;Rainer Heintzmann;Rainer Heintzmann;Heinrich Leonhardt

  • Subdiffraction Multicolor Imaging of the Nuclear Periphery with 3D Structured Illumination Microscopy

    Lothar Schermelleh;Peter M. Carlton;Sebastian Haase;Lin Shao

  • Super-resolution microscopy demystified

    L Schermelleh;A Ferrand;T Huser;C Eggeling

  • Targeting and tracing antigens in live cells with fluorescent nanobodies

    Ulrich Rothbauer;Kourosh Zolghadr;Sergey Tillib;Danny Nowak

  • Cortical Constriction During Abscission Involves Helices of ESCRT-III–Dependent Filaments

    Julien Guizetti;Julien Guizetti;Lothar Schermelleh;Jana Mäntler;Sandra Maar

  • Recruitment of DNA methyltransferase I to DNA repair sites.

    Oliver Mortusewicz;Lothar Schermelleh;Joachim Walter;M. Cristina Cardoso

  • Chromosome order in HeLa cells changes during mitosis and early G1, but is stably maintained during subsequent interphase stages

    Joachim Walter;Lothar Schermelleh;Marion Cremer;Satoshi Tashiro

  • 3D-structured illumination microscopy provides novel insight into architecture of human centrosomes.

    Katharina F. Sonnen;Lothar Schermelleh;Lothar Schermelleh;Heinrich Leonhardt;Erich A. Nigg

  • Targeting polycomb to pericentric heterochromatin in embryonic stem cells reveals a role for H2AK119u1 in PRC2 recruitment.

    Sarah Cooper;Martin Dienstbier;Raihann Hassan;Lothar Schermelleh

  • Spatial Preservation of Nuclear Chromatin Architecture during Three-Dimensional Fluorescence in Situ Hybridization (3D-FISH)

    Irina Solovei;Antonio Cavallo;Lothar Schermelleh;Françoise Jaunin

  • Chromatin domains and the interchromatin compartment form structurally defined and functionally interacting nuclear networks

    Heiner Albiez;Marion Cremer;Cinzia Tiberi;Lorella Vecchio

  • Strategic and practical guidelines for successful structured illumination microscopy

    Justin Demmerle;Cassandravictoria Innocent;Alison J North;Graeme Ball

  • Dynamics of Dnmt1 interaction with the replication machinery and its role in postreplicative maintenance of DNA methylation.

    Lothar Schermelleh;Andrea Haemmer;Fabio Spada;Nicole Rösing

  • SIMcheck: a Toolbox for Successful Super-resolution Structured Illumination Microscopy.

    Graeme Ball;Justin Demmerle;Rainer Kaufmann;Rainer Kaufmann;Ilan Davis

  • A Pooled shRNA Screen Identifies Rbm15, Spen, and Wtap as Factors Required for Xist RNA-Mediated Silencing

    Benoit Moindrot;Andrea Cerase;Heather Coker;Osamu Masui

  • PCGF3/5–PRC1 initiates Polycomb recruitment in X chromosome inactivation

    Mafalda Almeida;Greta Pintacuda;Osamu Masui;Yoko Koseki

  • DNMT1 but not its interaction with the replication machinery is required for maintenance of DNA methylation in human cells.

    Fabio Spada;Andrea Haemmer;David Kuch;Ulrich Rothbauer

  • Replication-independent chromatin loading of Dnmt1 during G2 and M phases.

    Hariharan P Easwaran;Lothar Schermelleh;Heinrich Leonhardt;Heinrich Leonhardt;M Cristina Cardoso

  • The potential of 3D-FISH and super-resolution structured illumination microscopy for studies of 3D nuclear architecture

    Yolanda Markaki;Daniel Smeets;Susanne Fiedler;Volker J. Schmid

  • Three-dimensional super-resolution microscopy of the inactive X chromosome territory reveals a collapse of its active nuclear compartment harboring distinct Xist RNA foci

    Daniel Smeets;Daniel Smeets;Yolanda Markaki;Volker J Schmid;Felix Kraus;Felix Kraus

Frequent Co-Authors

Heinrich Leonhardt
Heinrich Leonhardt Ludwig-Maximilians-Universität München
Thomas Cremer
Thomas Cremer Ludwig-Maximilians-Universität München
Neil Brockdorff
Neil Brockdorff University of Oxford
M. Cristina Cardoso
M. Cristina Cardoso Technical University of Darmstadt
Christoph Cremer
Christoph Cremer Heidelberg University
Volker Schmid
Volker Schmid Ludwig-Maximilians-Universität München
Veronica J. Buckle
Veronica J. Buckle University of Oxford
Tatyana B. Nesterova
Tatyana B. Nesterova University of Oxford
Thomas Carell
Thomas Carell Ludwig-Maximilians-Universität München
Elisabeth Kremmer
Elisabeth Kremmer Max Planck Society

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