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Frans C. S. Ramaekers

Frans C. S. Ramaekers

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Biology and Biochemistry
Netherlands
2023

D-Index & Metrics

Biology and Biochemistry

D-Index
94
Citations
31164
World Ranking
2022
National Ranking
41

Medicine

D-Index
93
Citations
30664
World Ranking
10920
National Ranking
432

Research.com Recognitions

  • 2023 - Research.com Biology and Biochemistry in Netherlands Leader Award

Overview

Frans C. S. Ramaekers is affiliated with Maastricht University in the Netherlands. Their research spans primarily the fields of Medicine as well as Biochemistry, Genetics, and Molecular Biology. Within these areas, their work focuses significantly on Hematology, Emergency Medicine, Molecular Biology, Orthopedics and Sports Medicine, and Genetics.

Their main research topics include Acute Myeloid Leukemia Research, Hematological disorders and diagnostics, Bone and Joint Diseases, Myeloproliferative Neoplasms: Diagnosis and Treatment, Nuclear Structure and Function, RNA Research and Splicing, and Cervical Cancer and HPV Research.

Some notable recent papers by Ramaekers and collaborators are:

  • Structural and Mechanical Aberrations of the Nuclear Lamina in Disease, 2020, Cells
  • Proliferative activity is disturbed in myeloproliferative neoplasms (MPN), myelodysplastic syndrome (MDS), and MDS/MPN diseases. Differences between MDS and MDS/MPN, 2020, Cytometry Part B Clinical Cytometry
  • Switches of SOX17 and SOX2 expression in the development of squamous metaplasia and squamous intraepithelial lesions of the uterine cervix, 2020, Cancer Medicine
  • Super-Resolution Imaging of the A- and B-Type Lamin Networks: A Comparative Study of Different Fluorescence Labeling Procedures, 2021, International Journal of Molecular Sciences
  • The Role of Lamins in the Nucleoplasmic Reticulum, a Pleiomorphic Organelle That Enhances Nucleo-Cytoplasmic Interplay, 2022, Frontiers in Cell and Developmental Biology

Ramaekers has frequently collaborated with several scientists, including:

  • Anton H. N. Hopman
  • Stefan G.C. Mestrum
  • Mathie P.G. Leers
  • Norbert C.J. De Wit
  • Roosmarie J.M. Drent

Their publications appear regularly in venues such as Zenodo (CERN European Organization for Nuclear Research), Cytometry Part B Clinical Cytometry, Data in Brief, Histochemistry and Cell Biology, and Cells.

Best Publications

  • Annexin V-affinity assay: a review on an apoptosis detection system based on phosphatidylserine exposure.

    Manon van Engeland;Luc J. W. Nieland;Frans C. S. Ramaekers;Bert Schutte

  • Immunocytochemical detection and mapping of a cytokeratin 18 neo-epitope exposed during early apoptosis.

    Mathie P. G. Leers;Wendy Kölgen;Viveka Björklund;Tomas Bergman

  • A NOVEL ASSAY TO MEASURE LOSS OF PLASMA MEMBRANE ASYMMETRY DURING APOPTOSIS OF ADHERENT CELLS IN CULTURE

    Manon van Engeland;Frans C.S. Ramaekers;Bert Schutte;Chris P.M. Reutelingsperger

  • Nuclear lamins: laminopathies and their role in premature ageing

    J. L. V. Broers;F. C. S. Ramaekers;G. Bonne;R. Ben Yaou

  • In situ hybridization as a tool to study numerical chromosome aberrations in solid bladder tumors.

    A. H. N. Hopman;F. C. S. Ramaekers;A. K. Raap;J. L. M. Beck

  • Contribution of mutations in the cytochrome P450 14α-demethylase (Erg11p, Cyp51p) to azole resistance in Candida albicans

    Patrick Marichal;Patrick Marichal;Luc Koymans;Staf Willemsens;Danny Bellens

  • Marked differences in survival rate between smokers and nonsmokers with HPV 16-associated tonsillar carcinomas

    Harriët C. Hafkamp;J.J. Manni;A. Haesevoets;A.C. Voogd

  • Decreased mechanical stiffness in LMNA−/− cells is caused by defective nucleo-cytoskeletal integrity: implications for the development of laminopathies

    Jos L.V. Broers;Emiel A.G. Peeters;Helma J.H. Kuijpers;Jorike Endert

  • Coexpression of keratin- and vimentin-type intermediate filaments in human metastatic carcinoma cells

    F. C. S. Ramaekers;D. Haag;A. Kant;O. Moesker

  • Rapid Synthesis of Biotin-, Digoxigenin-, Trinitrophenyl-, and Fluorochrome-labeled Tyramides and Their Application for In Situ Hybridization Using CARD Amplification

    Anton H.N. Hopman;Frans C.S. Ramaekers;Ernst J.M. Speel

  • A subset of head and neck squamous cell carcinomas exhibits integration of HPV 16/18 DNA and overexpression of p16INK4A and p53 in the absence of mutations in p53 exons 5–8

    Harriet C. Hafkamp;Ernst J.M. Speel;Annick Haesevoets;Fredrik J. Bot

  • Smoothelin, a novel cytoskeletal protein specific for smooth muscle cells

    F. T. L. Van Der Loop;G. Schaart;E. D. J. Timmer;F. C. S. Ramaekers

  • Numerical chromosome 1, 7, 9, and 11 aberrations in bladder cancer detected by in situ hybridization.

    A. H. N. Hopman;O. Moesker;A. W. G. B. Smeets;R. P. E. Pauwels

  • Transient expression of phosphatidylserine at cell-cell contact areas is required for myotube formation

    S.M. van den Eijnde;M.J.B. van den Hoff;C.P.M. Reutelingsperger;W.L. van Heerde

  • Dynamics of the nuclear lamina as monitored by GFP-tagged A-type lamins

    J.L.V. Broers;B.M. Machiels;G.J.J.M. van Eys;H.J.H. Kuijpers

  • Gene expression of tumor angiogenesis dissected: specific targeting of colon cancer angiogenic vasculature

    Judy R. van Beijnum;Ruud P. Dings;Ruud P. Dings;Edith van der Linden;Edith van der Linden;Bernadette M. M. Zwaans;Bernadette M. M. Zwaans

  • Identification of the sex of human preimplantation embryos in two hours using an improved spreading method and fluorescent in-situ hybridization (FISH) using directly labelled probes

    Joyce C. Harper;Edith Coonen;Frans C.S. Ramaekers;D.A. Joy Delhanty

  • Cytokeratins in Different Types of Human Lung Cancer as Monitored by Chain-specific Monoclonal Antibodies

    J. L. V. Broers;F. C. S. Ramaekers;M. K. Rot;T. Oostendorp

  • The inner nuclear membrane protein emerin regulates beta-catenin activity by restricting its accumulation in the nucleus.

    Ewa Markiewicz;Katarzyna Tilgner;Nick Barker;Mark van de Wetering

  • Detection of numerical chromosome aberrations using in situ hybridization in paraffin sections of routinely processed bladder cancers.

    Hopman Ah;van Hooren E;van de Kaa Ca;Vooijs Pg

Frequent Co-Authors

Jos L. V. Broers
Jos L. V. Broers Maastricht University
Manon van Engeland
Manon van Engeland Maastricht University
Joris A. Veltman
Joris A. Veltman University of Edinburgh
Hans Bloemendal
Hans Bloemendal Radboud University
Folkert Kuipers
Folkert Kuipers University Medical Center Groningen
Dieter Lütjohann
Dieter Lütjohann University Hospital Bonn
Chris P. M. Reutelingsperger
Chris P. M. Reutelingsperger Maastricht University
Irene M. Leigh
Irene M. Leigh University of Dundee
Aurel Perren
Aurel Perren University of Bern
Wan L. Lam
Wan L. Lam BC Cancer Research Centre

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