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Biology and Biochemistry

D-Index
98
Citations
30862
World Ranking
1694
National Ranking
943

Overview

Elizabeth Murphy is affiliated with the National Institutes of Health in the United States and has contributed extensively to the fields of biochemistry, genetics, molecular biology, and medicine. Their research primarily focuses on mitochondrial function and pathology, with significant exploration into ATP synthase, cardiac ischemia and reperfusion, and signaling pathways involved in disease.

The scientist's work spans multiple subfields including molecular biology, pathology and forensic medicine, cardiology and cardiovascular medicine, cancer research, and epidemiology. This multidisciplinary approach allows for insights into complex biological processes and disease mechanisms.

Elizabeth Murphy's recent publications reflect their focus on mitochondrial biology and cardiovascular health. Notable papers include:

  • "Role of Mitochondrial Calcium and the Permeability Transition Pore in Regulating Cell Death" (2020, Circulation Research)
  • "Mitochondrial permeability transition pore-dependent necrosis" (2022, Journal of Molecular and Cellular Cardiology)
  • "Cyclophilin D: An Integrator of Mitochondrial Function" (2020, Frontiers in Physiology)
  • "Mitochondrial calcium and reactive oxygen species in cardiovascular disease" (2022, Cardiovascular Research)
  • "Improving translational research in sex-specific effects of comorbidities and risk factors in ischaemic heart disease and cardioprotection: position paper and recommendations of the ESC Working Group on Cellular Biology of the Heart" (2020, Cardiovascular Research)

Frequent coauthors who have collaborated extensively with Elizabeth Murphy include Junhui Sun, Chengyu Liu, Danielle Springer, Julia Liu, and María M. Fergusson. These partnerships have contributed to a cohesive body of research within the mitochondrial and cardiovascular domains.

Their work is often published in specialized scientific journals, with repeated contributions found in:

  • Circulation Research
  • Journal of Molecular and Cellular Cardiology
  • Cardiovascular Research
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Journal of Molecular and Cellular Cardiology Plus

The main topics covered in Elizabeth Murphy's research include:

  • Mitochondrial Function and Pathology
  • ATP Synthase and ATPases Research
  • Cardiac Ischemia and Reperfusion
  • Signaling Pathways in Disease
  • Cancer, Hypoxia, and Metabolism
  • RNA modifications and cancer
  • Cardiovascular Function and Risk Factors

Best Publications

  • Mechanisms Underlying Acute Protection From Cardiac Ischemia-Reperfusion Injury

    Elizabeth Murphy;Charles Steenbergen

  • The physiological role of mitochondrial calcium revealed by mice lacking the mitochondrial calcium uniporter

    Xin Pan;Jie Liu;Tiffany Nguyen;Chengyu Liu

  • Deoxymyoglobin is a Nitrite Reductase That Generates Nitric Oxide and Regulates Mitochondrial Respiration

    Sruti Shiva;Zhi Huang;Rozalina Grubina;Junhui Sun

  • Estrogen Signaling and Cardiovascular Disease

    Elizabeth Murphy

  • Diazoxide-Induced Cardioprotection Requires Signaling Through a Redox-Sensitive Mechanism

    Robert A. Forbes;Charles Steenbergen;Elizabeth Murphy

  • Guidelines for experimental models of myocardial ischemia and infarction.

    Merry L. Lindsey;Merry L. Lindsey;Roberto Bolli;John M. Canty;Xiao Jun Du

  • Phosphorylation of Glycogen Synthase Kinase-3β During Preconditioning Through a Phosphatidylinositol-3-Kinase–Dependent Pathway Is Cardioprotective

    Haiyan Tong;Kenichi Imahashi;Charles Steenbergen;Elizabeth Murphy

  • Ischemic Preconditioning Activates Phosphatidylinositol-3-Kinase Upstream of Protein Kinase C

    Haiyan Tong;Weina Chen;Charles Steenbergen;Elizabeth Murphy

  • Cyclophilin D controls mitochondrial pore–dependent Ca2+ exchange, metabolic flexibility, and propensity for heart failure in mice

    John W. Elrod;Renee Wong;Shikha Mishra;Ronald J. Vagnozzi

  • Preconditioning Results in S-Nitrosylation of Proteins Involved in Regulation of Mitochondrial Energetics and Calcium Transport

    Junhui Sun;Meghan Morgan;Rong Fong Shen;Charles Steenbergen

  • Nuclear miRNA Regulates the Mitochondrial Genome in the Heart

    Samarjit Das;Marcella Ferlito;Oliver A. Kent;Karen Fox-Talbot

  • Mitochondrial Function, Biology, and Role in Disease A Scientific Statement From the American Heart Association

    Elizabeth Murphy;Hossein Ardehali;Robert S. Balaban;Fabio DiLisa

  • Enhanced Postischemic Functional Recovery in CYP2J2 Transgenic Hearts Involves Mitochondrial ATP-Sensitive K+ Channels and p42/p44 MAPK Pathway

    John Seubert;Baichun Yang;J. Alyce Bradbury;Joan Graves

  • Inhibition of δ-Protein Kinase C Protects Against Reperfusion Injury of the Ischemic Heart In Vivo

    Koichi Inagaki;Leon Chen;Fumiaki Ikeno;Felix H. Lee

  • Role of Mitochondrial Calcium and the Permeability Transition Pore in Regulating Cell Death.

    Tyler M. Bauer;Elizabeth Murphy

  • S-Nitrosylation: NO-Related Redox Signaling to Protect Against Oxidative Stress

    Junhui Sun;Charles Steenbergen;Elizabeth Murphy

  • The Nuclear Receptor ERRα Is Required for the Bioenergetic and Functional Adaptation to Cardiac Pressure Overload

    Janice M. Huss;Ken-ichi Imahashi;Catherine R. Dufour;Carla J. Weinheimer

  • Estrogen receptor-β mediates male-female differences in the development of pressure overload hypertrophy

    Maryanne Skavdahl;Charles Steenbergen;James Clark;Page Myers

  • Molecular Cloning, Expression, and Functional Significance of a Cytochrome P450 Highly Expressed in Rat Heart Myocytes

    Shu Wu;Weina Chen;Elizabeth Murphy;Scott Gabel

  • Erythropoietin receptor expression in adult rat cardiomyocytes is associated with an acute cardioprotective effect for recombinant erythropoietin during ischemia-reperfusion injury.

    Gary L. Wright;Paul Hanlon;Khalid Amin;Charles Steenbergen

Frequent Co-Authors

Charles Steenbergen
Charles Steenbergen Johns Hopkins University
Robert E. London
Robert E. London National Institutes of Health
Chengyu Liu
Chengyu Liu Southeast University
Michael N. Sack
Michael N. Sack National Institutes of Health
Toren Finkel
Toren Finkel University of Pittsburgh
Jeffery D. Molkentin
Jeffery D. Molkentin Cincinnati Children's Hospital Medical Center
Robert S. Balaban
Robert S. Balaban National Institutes of Health
Darryl C. Zeldin
Darryl C. Zeldin National Institutes of Health
Paolo Bernardi
Paolo Bernardi University of Padua
David Coghlan
David Coghlan Trinity College Dublin

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