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Molecular Biology

D-Index
56
Citations
19223
World Ranking
2182
National Ranking
1082

Overview

Amander T. Clark is affiliated with the University of California, Los Angeles, in the United States. Their research spans multiple areas within biochemistry, genetics, and molecular biology, with significant contributions to medicine as well. The primary focus of their work lies in molecular biology, reproductive medicine, genetics, physiology, and public health, environmental and occupational health subfields.

Clark's publications reflect extensive involvement in stem cell biology, reproductive biology, and genetic engineering. They have contributed numerous papers on topics including pluripotent stem cells, CRISPR and genetic engineering, reproductive biology and fertility, renal and related cancers, animal genetics and reproduction, biomedical ethics and regulation, and epigenetics and DNA methylation.

Some of the recent papers authored or co-authored by Clark are:

  • Human embryo research, stem cell-derived embryo models and in vitro gametogenesis: Considerations leading to the revised ISSCR guidelines (2021), published in Stem Cell Reports
  • Modelling human blastocysts by reprogramming fibroblasts into iBlastoids (2021), published in Nature
  • ISSCR Guidelines for Stem Cell Research and Clinical Translation: The 2021 update (2021), published in Stem Cell Reports
  • Reprogramming roadmap reveals route to human induced trophoblast stem cells (2020), published in Nature
  • Single-cell analysis of the developing human testis reveals somatic niche cell specification and fetal germline stem cell establishment (2021), published in Cell Stem Cell

Clark frequently collaborates with other scientists in the field. Their frequent co-authors include Fei-Man Hsu, Sissy E. Wamaitha, Enrique Sosa, Kathrin Plath, and Erica C. Pandolfi.

The venues where Clark most often publishes include:

  • Stem Cell Reports
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Stem Cell Research
  • Nature
  • Nature Communications

Their work primarily emphasizes pluripotent stem cells research and the use of CRISPR and genetic engineering techniques. Additional topics of research involve reproductive biology, fertility, biomedical ethics, regulation, and epigenetic modifications, including DNA methylation.

Best Publications

  • UHRF1 Plays a Role in Maintaining DNA Methylation in Mammalian Cells

    Magnolia Bostick;Jong Kyong Kim;Pierre-Olivier Estève;Amander Clark

  • Generation of human induced pluripotent stem cells from dermal fibroblasts

    W. E. Lowry;L. Richter;R. Yachechko;A. D. Pyle

  • Induced Pluripotent Stem Cells and Embryonic Stem Cells Are Distinguished by Gene Expression Signatures

    Mark H. Chin;Mike J. Mason;Wei Xie;Stefano Volinia

  • Hydrodynamic stretching of single cells for large population mechanical phenotyping

    Daniel R. Gossett;Henry T. K. Tse;Serena A. Lee;Yong Ying

  • IDENTIFICATION AND CLASSIFICATION OF CHROMOSOMAL ABERRATIONS IN HUMAN INDUCED PLURIPOTENT STEM CELLS

    Yoav Mayshar;Uri Ben-David;Neta Lavon;Juan-Carlos Biancotti

  • Relationship between nucleosome positioning and DNA methylation.

    Ramakrishna K. Chodavarapu;Suhua Feng;Yana V. Bernatavichute;Pao Yang Chen

  • Paracrine Actions Of Growth Differentiation Factor-9 in the Mammalian Ovary

    Julia A. Elvin;Amander T. Clark;Pei Wang;Neil M. Wolfman

  • Spontaneous differentiation of germ cells from human embryonic stem cells in vitro

    Amander T. Clark;Megan S. Bodnar;Mark Fox;Ryan T. Rodriquez

  • Human embryonic stem cell genes OCT4, NANOG, STELLAR, and GDF3 are expressed in both seminoma and breast carcinoma

    Uche I. Ezeh;Paul J. Turek;Renee A. Reijo;Amander T. Clark

  • Directed differentiation of human-induced pluripotent stem cells generates active motor neurons.

    Saravanan Karumbayaram;Bennett G. Novitch;Michaela Patterson;Joy A. Umbach

  • Unique gene expression signatures of independently-derived human embryonic stem cell lines

    Michael J. Abeyta;Amander T. Clark;Ryan T. Rodriguez;Megan S. Bodnar

  • Mitochondrial Function Controls Proliferation and Early Differentiation Potential of Embryonic Stem Cells

    Sudip Mandal;Sudip Mandal;Anne G. Lindgren;Anand S. Srivastava;Amander T. Clark

  • DNA Demethylation Dynamics in the Human Prenatal Germline

    Sofia Gkountela;Kelvin X. Zhang;Tiasha A. Shafiq;Wen-Wei Liao

  • Female Human iPSCs Retain an Inactive X Chromosome

    Jason Tchieu;Edward Kuoy;Mark H. Chin;Hung Trinh

  • Derivation of primordial germ cells from human embryonic and induced pluripotent stem cells is significantly improved by coculture with human fetal gonadal cells.

    Tae Sub Park;Zoran Galic;Anne E. Conway;Anne Lindgren

  • Human STELLAR, NANOG, and GDF3 genes are expressed in pluripotent cells and map to chromosome 12p13, a hotspot for teratocarcinoma.

    Amander T. Clark;Ryan T. Rodriguez;Megan S. Bodnar;Michael J. Abeyta

  • Naive Human Pluripotent Cells Feature a Methylation Landscape Devoid of Blastocyst or Germline Memory.

    William A. Pastor;Di Chen;Wanlu Liu;Rachel Kim

  • Bone Morphogenetic Proteins Induce Germ Cell Differentiation from Human Embryonic Stem Cells

    Kehkooi Kee;Joanna M. Gonsalves;Amander T. Clark;Renee A. Reijo Pera

  • Nuclear Localization of Mitochondrial TCA Cycle Enzymes as a Critical Step in Mammalian Zygotic Genome Activation.

    Raghavendra Nagaraj;Mark S. Sharpley;Fangtao Chi;Daniel Braas

  • Modelling human blastocysts by reprogramming fibroblasts into iBlastoids

    Xiaodong Liu;Xiaodong Liu;Xiaodong Liu;Jia Ping Tan;Jia Ping Tan;Jia Ping Tan;Jan Schröder;Jan Schröder;Jan Schröder;Asma Aberkane

Frequent Co-Authors

Kathrin Plath
Kathrin Plath University of California, Los Angeles
Renee A. Reijo Pera
Renee A. Reijo Pera California Polytechnic State University
Steven E. Jacobsen
Steven E. Jacobsen University of California, Los Angeles
Jose M. Polo
Jose M. Polo Monash University
Kyle E. Orwig
Kyle E. Orwig University of Pittsburgh
Matteo Pellegrini
Matteo Pellegrini University of California, Los Angeles
Nissim Benvenisty
Nissim Benvenisty Hebrew University of Jerusalem
Michael A. Teitell
Michael A. Teitell University of California, Los Angeles
Ryan Lister
Ryan Lister University of Western Australia

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