World's Best Scientists 2026 revealed!

D-Index & Metrics

Immunology

D-Index
105
Citations
47404
World Ranking
582
National Ranking
346

Medicine

D-Index
106
Citations
47785
World Ranking
6453
National Ranking
3432

Overview

Mario Castro is affiliated with Washington University in St. Louis in the United States and specializes in medical research with a focus on pulmonary and respiratory medicine.

Their primary field of study is Medicine, with significant contributions in the following subfields:

  • Pulmonary and Respiratory Medicine
  • Physiology
  • Immunology
  • Surgery
  • Infectious Diseases

The main research topics Mario Castro has worked on include:

  • Asthma and respiratory diseases
  • Respiratory and Cough-Related Research
  • IL-33, ST2, and ILC Pathways
  • Chronic Obstructive Pulmonary Disease (COPD) Research
  • Inhalation and Respiratory Drug Delivery
  • Eosinophilic Esophagitis
  • Allergic Rhinitis and Sensitization

They have published extensively in several academic journals. Frequent publication venues include:

  • American Journal of Respiratory and Critical Care Medicine
  • Journal of Allergy and Clinical Immunology
  • The Journal of Allergy and Clinical Immunology In Practice
  • CHEST Journal
  • bioRxiv (Cold Spring Harbor Laboratory)

Noteworthy recent papers by Mario Castro include:

  • COVID-19-related Genes in Sputum Cells in Asthma. Relationship to Demographic Features and Corticosteroids (2020, American Journal of Respiratory and Critical Care Medicine)
  • Evidence for Exacerbation-Prone Asthma and Predictive Biomarkers of Exacerbation Frequency (2020, American Journal of Respiratory and Critical Care Medicine)
  • Understanding the key issues in the treatment of uncontrolled persistent asthma with type 2 inflammation (2021, European Respiratory Journal)
  • Short-course systemic corticosteroids in asthma: striking the balance between efficacy and safety (2020, European Respiratory Review)
  • Mucus Plugs Persist in Asthma, and Changes in Mucus Plugs Associate with Changes in Airflow over Time (2022, American Journal of Respiratory and Critical Care Medicine)

Mario Castro has collaborated frequently with several co-authors in the field, including:

  • Elliot Israel
  • Sally E. Wenzel
  • Bruce D. Levy
  • Nizar N. Jarjour
  • Serpil C. Erzurum

Best Publications

  • International ERS/ATS guidelines on definition, evaluation and treatment of severe asthma

    Kian Fan Chung;Sally E. Wenzel;Jan L. Brozek;Andrew Bush

  • Identification of Asthma Phenotypes Using Cluster Analysis in the Severe Asthma Research Program

    Wendy C. Moore;Deborah A. Meyers;Sally E. Wenzel;W. Gerald Teague

  • Dupilumab Efficacy and Safety in Moderate-to-Severe Uncontrolled Asthma

    Mario Castro;Jonathan Corren;Ian D. Pavord;Jorge Maspero

  • Reslizumab for inadequately controlled asthma with elevated blood eosinophil counts: results from two multicentre, parallel, double-blind, randomised, placebo-controlled, phase 3 trials

    Mario Castro;James Zangrilli;Michael E Wechsler;Eric D Bateman

  • Efficacy and Safety of Dupilumab in Glucocorticoid-Dependent Severe Asthma.

    Klaus F. Rabe;Parameswaran Nair;Guy Brusselle;Jorge F. Maspero

  • Dupilumab efficacy and safety in adults with uncontrolled persistent asthma despite use of medium-to-high-dose inhaled corticosteroids plus a long-acting β2 agonist: a randomised double-blind placebo-controlled pivotal phase 2b dose-ranging trial

    Sally Wenzel;Mario Castro;Jonathan Corren;Jorge Maspero

  • Characterization of the severe asthma phenotype by the National Heart, Lung, and Blood Institute's Severe Asthma Research Program

    Wendy C. Moore;Eugene R. Bleecker;Douglas Curran-Everett;Serpil C. Erzurum

  • Meta-analysis of genome-wide association studies of asthma in ethnically diverse North American populations

    Dara G. Torgerson;Dara G. Torgerson;Elizabeth J. Ampleford;Grace Y. Chiu;W. James Gauderman

  • Effectiveness and safety of bronchial thermoplasty in the treatment of severe asthma: A multicenter, randomized, double-blind, sham-controlled clinical trial

    Mario Castro;Adalberto S. Rubin;Michel Laviolette;Jussara Fiterman

  • Reslizumab for Poorly Controlled, Eosinophilic Asthma: A Randomized, Placebo-Controlled Study

    Mario Castro;Sameer Mathur;Frederick Hargreave;Louis-Philippe Boulet

  • Airway microbiota and bronchial hyperresponsiveness in patients with suboptimally controlled asthma.

    Yvonne J. Huang;Craig E. Nelson;Eoin L. Brodie;Todd Z. DeSantis

  • Tiotropium bromide step-up therapy for adults with uncontrolled asthma

    Stephen P. Peters;Susan J. Kunselman;Nikolina Icitovic;Wendy C. Moore

  • Persistent activation of an innate immune response translates respiratory viral infection into chronic lung disease.

    Edy Y Kim;John T Battaile;Anand C Patel;Yingjian You

  • Management of severe asthma: a European Respiratory Society/American Thoracic Society guideline

    Fernando Holguin;Juan Carlos Cardet;Kian Fan Chung;Sarah Diver

  • Heterogeneity of severe asthma in childhood: confirmation by cluster analysis of children in the National Institutes of Health/National Heart, Lung, and Blood Institute Severe Asthma Research Program.

    Anne M. Fitzpatrick;W. Gerald Teague;Deborah A. Meyers;Stephen P. Peters

  • Mucus plugs in patients with asthma linked to eosinophilia and airflow obstruction

    Eleanor M. Dunican;Brett M. Elicker;David S. Gierada;Scott K. Nagle

  • Benralizumab, an anti-interleukin 5 receptor α monoclonal antibody, versus placebo for uncontrolled eosinophilic asthma: a phase 2b randomised dose-ranging study

    Mario Castro;Sally E Wenzel;Eugene R Bleecker;Emilio Pizzichini

  • Plasma interleukin-6 concentrations, metabolic dysfunction, and asthma severity: a cross-sectional analysis of two cohorts

    Michael C Peters;Kelly Wong McGrath;Gregory A Hawkins;Annette T Hastie

  • Obesity and asthma, an association modified by age of asthma onset

    Fernando Holguin;Eugene R. Bleecker;William W. Busse;William J. Calhoun

  • Efficacy of esomeprazole for treatment of poorly controlled asthma.

    John G. Mastronarde;Nicholas R. Anthonisen;Mario Castro

  • COVID-19-related Genes in Sputum Cells in Asthma. Relationship to Demographic Features and Corticosteroids.

    Michael C. Peters;Satria Sajuthi;Peter Deford;Stephanie Christenson

Frequent Co-Authors

Sally E. Wenzel
Sally E. Wenzel University of Pittsburgh
Elliot Israel
Elliot Israel Brigham and Women's Hospital
Eugene R. Bleecker
Eugene R. Bleecker University of Arizona
Nizar N. Jarjour
Nizar N. Jarjour University of Wisconsin–Madison
Serpil C. Erzurum
Serpil C. Erzurum Cleveland Clinic Lerner College of Medicine
Wendy C. Moore
Wendy C. Moore Wake Forest University
William W. Busse
William W. Busse University of Wisconsin–Madison
Stephen P. Peters
Stephen P. Peters Wake Forest University
John V. Fahy
John V. Fahy University of California, San Francisco
Benjamin Gaston
Benjamin Gaston Indiana University

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