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Hiroshi Kobayashi

Hiroshi Kobayashi

D-Index & Metrics

Biology and Biochemistry

D-Index
68
Citations
14111
World Ranking
7918
National Ranking
536

Overview

Hiroshi Kobayashi is affiliated with Nara Medical University in Japan and has a research focus primarily within the field of Medicine. Their work emphasizes reproductive medicine and obstetrics and gynecology, with significant contributions also in molecular biology, immunology, and public health-related fields.

The scientist's publication record includes papers that address endometriosis, adenomyosis, and reproductive system disorders, often exploring the intersection of pathological conditions with clinical outcomes. Notable recent publications include:

  • Brainstem Organoids From Human Pluripotent Stem Cells (2020, Frontiers in Neuroscience)
  • Relationship between adenomyosis and endometriosis; Different phenotypes of a single disease? (2020, European Journal of Obstetrics & Gynecology and Reproductive Biology)
  • A Relationship Between Endometriosis and Obstetric Complications (2020, Reproductive Sciences)
  • A Classification Proposal for Adenomyosis Based on Magnetic Resonance Imaging (2020, Gynecologic and Obstetric Investigation)
  • Prognostic value of pre-treatment systemic immune-inflammation index in patients with endometrial cancer (2021, PLoS ONE)

Key recurring themes in Kobayashi's work involve the research and treatment of endometriosis and related reproductive system issues. The main topics addressed in the scientific output include:

  • Endometriosis Research and Treatment
  • Endometrial and Cervical Cancer Treatments
  • Uterine Myomas and Treatments
  • Reproductive System and Pregnancy
  • Ovarian cancer diagnosis and treatment
  • Reproductive Biology and Fertility
  • Pregnancy and preeclampsia studies

Kobayashi has also collaborated extensively with a number of frequent coauthors, reflecting ongoing research partnerships. These include:

  • Shogo Imanaka
  • Hiroshi Shigetomi
  • Sho Matsubara
  • Naoki Kawahara
  • Chiharu Yoshimoto

The scientist's work has been published across several journals, with multiple articles in the following venues:

  • Journal of obstetrics and gynaecology research
  • Reproductive Sciences
  • Gynecologic and Obstetric Investigation
  • International Journal of Molecular Sciences
  • World Academy of Sciences Journal

The range of topics and frequent publication in reputable specialty journals indicate a focused research trajectory in reproductive health issues, combining clinical investigation with molecular and immunological perspectives. Kobayashi's contributions add to the scientific understanding of female reproductive disorders and associated complications during pregnancy.

Best Publications

  • Cathepsin B efficiently activates the soluble and the tumor cell receptor-bound form of the proenzyme urokinase-type plasminogen activator (Pro-uPA).

    H Kobayashi;M Schmitt;L Goretzki;N Chucholowski

  • Risk of developing ovarian cancer among women with ovarian endometrioma: a cohort study in Shizuoka, Japan.

    H. Kobayashi;K. Sumimoto;N. Moniwa;M. Imai

  • A Randomized Study of Screening for Ovarian Cancer : A Multicenter Study in Japan

    H. Kobayashi;Y. Yamada;T. Sado;M. Sakata

  • Inhibition of in Vitro Ovarian Cancer Cell Invasion by Modulation of Urokinase- type Plasminogen Activator and Cathepsin B

    Hiroshi Kobayashi;Hidekazu Ohi;Motoi Sugimura;Hiromitsu Shinohara

  • Ovarian endometrioma—Risks factors of ovarian cancer development

    Hiroshi Kobayashi;Kazuhiro Sumimoto;Takashi Kitanaka;Yoshihiko Yamada

  • Serum sialyl Tn as an independent predictor of poor prognosis in patients with epithelial ovarian cancer

    H Kobayashi;T Terao;Y Kawashima

  • The role of hyaluronic acid as a mediator and regulator of cervical ripening.

    Emad El Maradny;N. Kanayama;H. Kobayashi;B. Hossain

  • Hereditary breast and ovarian cancer susceptibility genes (Review)

    Hiroshi Kobayashi;Sumire Ohno;Yoshikazu Sasaki;Miyuki Matsuura

  • Impact of urokinase-type plasminogen activator and its inhibitor type 1 on prognosis in cervical cancer of the uterus.

    Hiroshi Kobayashi;Suguru Fujishiro;Toshihiko Terao

  • Immunologic studies in presumed amniotic fluid embolism.

    Michael D Benson;Hiroshi Kobayashi;Richard K Silver;Hidekazu Oi

  • Inhibitory Effect of a Conjugate between Human Urokinase and Urinary Trypsin Inhibitor on Tumor Cell Invasion in Vitro

    Hiroshi Kobayashi;Junko Gotoh;Yasuyuki Hirashima;Michio Fujie

  • Suppressing effects of daily oral supplementation of beta-glucan extracted from Agaricus blazei Murill on spontaneous and peritoneal disseminated metastasis in mouse model

    Hiroshi Kobayashi;Ryuji Yoshida;Yasufumi Kanada;Yoichi Fukuda

  • Pathogenesis of endometriosis: the role of initial infection and subsequent sterile inflammation (Review).

    Hiroshi Kobayashi;Yumi Higashiura;Hiroshi Shigetomi;Hirotaka Kajihara

  • Effects of membrane-associated cathepsin B on the activation of receptor-bound prourokinase and subsequent invasion of reconstituted basement membranes

    Hiroshi Kobayashi;Nobuhiko Moniwa;Motoi Sugimura;Hiromitsu Shinohara

  • Hyaluronic acid-specific regulation of cytokines by human uterine fibroblasts

    Hiroshi Kobayashi;Toshihiko Terao

  • Molecular pathogenesis of endometriosis-associated clear cell carcinoma of the ovary (review).

    Hiroshi Kobayashi;Hirotaka Kajiwara;Seiji Kanayama;Yoshihiko Yamada

  • Inhibition of metastasis of Lewis lung carcinoma by a synthetic peptide within growth factor-like domain of urokinase in the experimental and spontaneous metastasis model.

    Hiroshi Kobayashi;Junko Gotoh;Michio Fujie;Hiromitsu Shinohara

  • The protease inhibitor bikunin, a novel anti-metastatic agent.

    Hiroshi Kobayashi;Mika Suzuki;Yasuyuki Hirashima;Toshihiko Terao

  • A soybean Kunitz trypsin inhibitor suppresses ovarian cancer cell invasion by blocking urokinase upregulation.

    Hiroshi Kobayashi;Mika Suzuki;Naohiro Kanayama;Toshihiko Terao

  • Clinical implications of idiopathic multicentric castleman disease among Japanese: a report of 28 cases.

    Masaru Kojima;Naoya Nakamura;Norihumi Tsukamoto;Yoshiro Otuski

Frequent Co-Authors

Toshihiko Terao
Toshihiko Terao Hamamatsu University
Masaharu Takigawa
Masaharu Takigawa Okayama University
Eleftherios P. Diamandis
Eleftherios P. Diamandis Mount Sinai Hospital
Fumitaka Kikkawa
Fumitaka Kikkawa Nagoya University
Yasuhiro Yamada
Yasuhiro Yamada University of Tokyo
Tetsuhito Kojima
Tetsuhito Kojima Nagoya University
Masafumi Tsujimoto
Masafumi Tsujimoto Gifu Pharmaceutical University
Toyoaki Murohara
Toyoaki Murohara Nagoya University
Shigeo Nakamura
Shigeo Nakamura Nagoya University
Yasuhito Tanaka
Yasuhito Tanaka Kumamoto University

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