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Biology and Biochemistry
Spain
2023

D-Index & Metrics

Biology and Biochemistry

D-Index
91
Citations
21120
World Ranking
2373
National Ranking
27

Research.com Recognitions

  • 2023 - Research.com Biology and Biochemistry in Spain Leader Award

Overview

Carmen Lluis is affiliated with the University of Barcelona in Spain and conducts research primarily within the fields of Biochemistry, Genetics and Molecular Biology, and Neuroscience. Their work spans several subfields including Cellular and Molecular Neuroscience, Molecular Biology, Biochemistry, and Physiology. The main topics addressed in their research include Genetic Neurodegenerative Diseases, Neurotransmitter Receptor Influence on Behavior, Biochemical Acid Research Studies, Adenosine and Purinergic Signaling, Chemical Synthesis and Analysis, and RNA Interference and Gene Delivery.

Their recent publications cover a range of neuropharmacological and biochemical themes. One notable paper is titled "Modulation of dopamine D1 receptors via histamine H3 receptors is a novel therapeutic target for Huntington's disease", published in 2020 in eLife. Another publication, "Correction to: A1R-A2AR heteromers coupled to Gs and Gi/0 proteins modulate GABA transport into astrocytes", appeared in 2024 in the journal Purinergic Signalling. These papers reflect the focus on receptor modulation and signaling pathways in neurological contexts.

Carmen Lluis has collaborated with a set of frequent co-authors, notably including Vicent Casadó and Peter J. McCormick, with two publications each. Additional collaborators with whom they have worked include David Moreno-Delgado, Mar Puigdellívol, and Estefanía Moreno.

Their work has appeared in journals such as eLife and Purinergic Signalling, indicating involvement in both broad biomedical research and more specialized purinergic signaling studies.

  • Main Fields of Study: Biochemistry, Genetics and Molecular Biology; Neuroscience
  • Subfields of Study: Cellular and Molecular Neuroscience; Molecular Biology; Biochemistry; Physiology
  • Main Topics of Work: Genetic Neurodegenerative Diseases; Neurotransmitter Receptor Influence on Behavior; Biochemical Acid Research Studies; Adenosine and Purinergic Signaling; Chemical Synthesis and Analysis; RNA Interference and Gene Delivery
  • Recent Papers: "Modulation of dopamine D1 receptors via histamine H3 receptors is a novel therapeutic target for Huntington's disease" (2020, eLife); "Correction to: A1R-A2AR heteromers coupled to Gs and Gi/0 proteins modulate GABA transport into astrocytes" (2024, Purinergic Signalling)
  • Frequent Co-authors: Vicent Casadó; Peter J. McCormick; David Moreno-Delgado; Mar Puigdellívol; Estefanía Moreno
  • Frequent Publication Venues: eLife; Purinergic Signalling

Best Publications

  • Presynaptic Control of Striatal Glutamatergic Neurotransmission by Adenosine A1–A2A Receptor Heteromers

    Francisco Ciruela;Vicent Casadó;Ricardo J. Rodrigues;Rafael Luján

  • Coaggregation, cointernalization, and codesensitization of adenosine A2A receptors and dopamine D2 receptors

    Joëlle A. Hillion;Meritxell Canals;Maria Torvinen;Vicent Casado

  • Dopamine D1 and adenosine A1 receptors form functionally interacting heteromeric complexes

    Silvia Ginés;Joëlle Hillion;Maria Torvinen;Stèphane Le Crom

  • Synergistic interaction between adenosine A2A and glutamate mGlu5 receptors: implications for striatal neuronal function.

    Sergi Ferré;Marzena Karcz-Kubicha;Bruce T. Hope;Patrizia Popoli

  • Molecular Mechanisms and Therapeutical Implications of Intramembrane Receptor/Receptor Interactions among Heptahelical Receptors with Examples from the Striatopallidal GABA Neurons

    Luigi F. Agnati;Sergi Ferré;Carme Lluis;Rafael Franco

  • Detection of heteromerization of more than two proteins by sequential BRET-FRET.

    Paulina Carriba;Gemma Navarro;Francisco Ciruela;Sergi Ferré

  • METABOTROPIC GLUTAMATE TYPE 5, DOPAMINE D2 AND ADENOSINE A2A RECEPTORS FORM HIGHER-ORDER OLIGOMERS IN LIVING CELLS

    Nuria Cabello;Jorge Gandía;Daniela C. G. Bertarelli;Masahiko Watanabe

  • Striatal adenosine A2A and cannabinoid CB1 receptors form functional heteromeric complexes that mediate the motor effects of cannabinoids.

    Paulina Carriba;Oskar Ortiz;Kshitij Patkar;Zuzana Justinova;Zuzana Justinova

  • Cell surface adenosine deaminase: Much more than an ectoenzyme

    Rafael Franco;Vicent Casadó;Francisco Ciruela;Carles Saura

  • Receptor heteromerization in adenosine A2A receptor signaling Relevance for striatal function and Parkinson’s disease

    Kjell Fuxe;L. F. Agnati;K. Jacobsen;J. Hillion

  • An Update on Adenosine A2A-Dopamine D2 Receptor Interactions: Implications for the Function of G Protein-Coupled Receptors

    Sergi Ferré;César Quiroz;A S Woods;Rodrigo Antunes Cunha

  • Cannabinoid receptors CB1 and CB2 form functional heteromers in brain.

    Lucía Callén;Lucía Callén;Estefanía Moreno;Estefanía Moreno;Pedro Barroso-Chinea;David Moreno-Delgado;David Moreno-Delgado

  • Adenosine A2A and dopamine D2 heteromeric receptor complexes and their function

    Kjell Fuxe;Sergi Ferré;Meritxell Canals;Maria Torvinen

  • CD26, adenosine deaminase, and adenosine receptors mediate costimulatory signals in the immunological synapse

    R. Pacheco;J. M. Martinez-Navio;M. Lejeune;N. Climent

  • Identification of dopamine D1-D3 receptor heteromers: Indications for a role of synergistic D1-D3 receptor interactions in the striatum

    Daniel Marcellino;Sergi Ferré;Vicent Casadó;Antonio Cortés

  • Combining mass spectrometry and pull-down techniques for the study of receptor heteromerization. Direct epitope-epitope electrostatic interactions between adenosine A2A and dopamine D2 receptors.

    Francisco Ciruela;Javier Burgueño;Vicent Casadó;Meritxell Canals

  • Enzymatic and extraenzymatic role of ecto‐adenosine deaminase in lymphocytes

    Rafael Franco;Agustin Valenzuela;Carmen Lluis;Julia Blanco

  • A1 adenosine receptors accumulate in neurodegenerative structures in Alzheimer disease and mediate both amyloid precursor protein processing and tau phosphorylation and translocation.

    Ester Angulo;Vicent Casadó;Josefa Mallol;Enric I. Canela

  • Metabotropic Glutamate 1α and Adenosine A1 Receptors Assemble into Functionally Interacting Complexes

    Francisco Ciruela;Francisco Ciruela;Marisol Escriche;Javier Burgueño;Ester Angulo

  • Receptor heteromerization in adenosine A2A receptor signaling

    K. Fuxe;Luigi Francesco Agnati;K. Jacobsen;J. Hillion

Frequent Co-Authors

Rafael Franco
Rafael Franco University of Barcelona
Enric I. Canela
Enric I. Canela University of Barcelona
Josefa Mallol
Josefa Mallol University of Barcelona
Vicent Casadó
Vicent Casadó University of Barcelona
Sergi Ferré
Sergi Ferré National Institute on Drug Abuse
Francisco Ciruela
Francisco Ciruela University of Barcelona
Kjell Fuxe
Kjell Fuxe Karolinska Institute
Gemma Navarro
Gemma Navarro University of Barcelona
Luigi F. Agnati
Luigi F. Agnati University of Modena and Reggio Emilia
Julià Blanco
Julià Blanco IrsiCaixa

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