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Materials Science

D-Index
48
Citations
21359
World Ranking
10690
National Ranking
2526

Overview

William M. Shih is a researcher affiliated with Harvard Medical School in the United States. Their work spans primarily in the fields of Biochemistry, Genetics and Molecular Biology, with a total of 53 publications. Subfields of study include Molecular Biology, Ecology, Biomedical Engineering, Atomic and Molecular Physics, and Optics, as well as Immunology.

The main topics covered in Shih's research are advanced biosensing and bioanalysis techniques, RNA interference and gene delivery, bacteriophages and microbial interactions, force microscopy techniques and applications, DNA and nucleic acid chemistry, biosensors and analytical detection, and immunotherapy and immune responses.

Shih has coauthored numerous papers with several frequent collaborators, including:

  • Christopher M. Wintersinger
  • Ju Hee Ryu
  • Yang Zeng
  • Olivia J. Young
  • Anastasia Ershova

Their research is published in a variety of scientific journals, with frequent appearances in the following venues:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Journal of the American Chemical Society
  • Nature Nanotechnology
  • Biophysical Journal
  • Nature Communications

Some recent publications authored by Shih include:

  • "Glutaraldehyde Cross-Linking of Oligolysines Coating DNA Origami Greatly Reduces Susceptibility to Nuclease Degradation" (2020, Journal of the American Chemical Society)
  • "Precise pitch-scaling of carbon nanotube arrays within three-dimensional DNA nanotrenches" (2020, Science)
  • "A Local Computing Cell and 6T SRAM-Based Computing-in-Memory Macro With 8-b MAC Operation for Edge AI Chips" (2021, IEEE Journal of Solid-State Circuits)
  • "Fine tuning of CpG spatial distribution with DNA origami for improved cancer vaccination" (2024, Nature Nanotechnology)
  • "Multi-micron crisscross structures grown from DNA-origami slats" (2022, Nature Nanotechnology)

Best Publications

  • Self-assembly of DNA into nanoscale three-dimensional shapes

    Shawn M. Douglas;Hendrik Dietz;Tim Liedl;Björn Högberg

  • Folding DNA into Twisted and Curved Nanoscale Shapes

    Hendrik Dietz;Shawn M. Douglas;Shawn M. Douglas;William M. Shih;William M. Shih

  • Challenges and opportunities for structural DNA nanotechnology

    Andre V. Pinheiro;Dongran Han;William M. Shih;Hao Yan

  • Rapid prototyping of 3D DNA-origami shapes with caDNAno

    Shawn Michael Douglas;Adam H. Marblestone;Surat Teerapittayanon;Alejandro Vazquez

  • Three-Dimensional Structures Self-Assembled from DNA Bricks

    Yonggang Ke;Yonggang Ke;Luvena L. Ong;Luvena L. Ong;William M. Shih;William M. Shih;Peng Yin;Peng Yin

  • A 1.7-kilobase single-stranded DNA that folds into a nanoscale octahedron

    William M. Shih;Joel D. Quispe;Gerald F. Joyce

  • Multiplexed 3D cellular super-resolution imaging with DNA-PAINT and Exchange-PAINT

    Ralf Jungmann;Maier S Avendaño;Johannes B Woehrstein;Mingjie Dai

  • DNA-nanotube-induced alignment of membrane proteins for NMR structure determination

    Shawn M. Douglas;James J. Chou;William M. Shih

  • Virus-Inspired Membrane Encapsulation of DNA Nanostructures To Achieve In Vivo Stability

    Steven D. Perrault;William M. Shih

  • Tug-of-war in motor protein ensembles revealed with a programmable DNA origami scaffold.

    N. D. Derr;B. S. Goodman;R. Jungmann;R. Jungmann;A. E. Leschziner

  • Oligolysine-based coating protects DNA nanostructures from low-salt denaturation and nuclease degradation

    Nandhini Ponnuswamy;Nandhini Ponnuswamy;Maartje M. C. Bastings;Maartje M. C. Bastings;Bhavik Nathwani;Bhavik Nathwani;Ju Hee Ryu

  • Multilayer DNA origami packed on a square lattice.

    Yonggang Ke;Shawn M. Douglas;Minghui Liu;Jaswinder Sharma

  • Self-assembly of three-dimensional prestressed tensegrity structures from DNA

    Tim Liedl;Björn Högberg;Björn Högberg;Jessica Tytell;Donald E. Ingber

  • Mitochondrial uncoupling protein 2 structure determined by NMR molecular fragment searching

    Marcelo J. Berardi;William M. Shih;William M. Shih;Stephen C. Harrison;Stephen C. Harrison;James J. Chou

  • Addressing the Instability of DNA Nanostructures in Tissue Culture

    Jaeseung Hahn;Shelley F. J. Wickham;William M. Shih;Steven D. Perrault

  • Using DNA to program the self-assembly of colloidal nanoparticles and microparticles

    W. Benjamin Rogers;W. Benjamin Rogers;William M. Shih;William M. Shih;Vinothan N. Manoharan

  • Submicrometre geometrically encoded fluorescent barcodes self-assembled from DNA

    Chenxiang Lin;Ralf Jungmann;Ralf Jungmann;Andrew Michael Leifer;Andrew Michael Leifer;Chao Li;Chao Li

  • A clathrin-binding site in the hinge of the beta 2 chain of mammalian AP-2 complexes.

    William Shih;Andreas Gallusser;Tomas Kirchhausen

  • Prescribed nanoparticle cluster architectures and low-dimensional arrays built using octahedral DNA origami frames

    Ye Tian;Tong Wang;Wenyan Liu;Huolin L. Xin

  • Self-assembly of size-controlled liposomes on DNA nanotemplates

    Yang Yang;Jing Wang;Hideki Shigematsu;Weiming Xu

  • Self-Assembly of DNA into Nanoscale Three-Dimensional Shapes

    William Shih

Frequent Co-Authors

Ralf Jungmann
Ralf Jungmann Max Planck Society
Yonggang Ke
Yonggang Ke Georgia Institute of Technology
Tim Liedl
Tim Liedl Ludwig-Maximilians-Universität München
George M. Church
George M. Church Harvard University
Gerhard Wagner
Gerhard Wagner Harvard University
Donald E. Ingber
Donald E. Ingber Harvard University
Hiroshi Sasaki
Hiroshi Sasaki Jikei University School of Medicine
David J. Mooney
David J. Mooney Harvard University
Hao Yan
Hao Yan Arizona State University
Wei Sun
Wei Sun Drexel University

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