2007 - Hellman Fellow
His scientific interests lie mostly in Neuroscience, Dopamine, Dopaminergic, Nucleus accumbens and Pharmacology. He is interested in GABAergic, which is a branch of Neuroscience. His research in Dopamine is mostly concerned with Striatum.
His Dopaminergic research incorporates elements of Glial cell line-derived neurotrophic factor and Neurotrophic factors. His Nucleus accumbens study combines topics from a wide range of disciplines, such as Cannabinoid and Addiction. His Pharmacology research is multidisciplinary, relying on both Sprague dawley and Organ Culture Technique.
Alexander F. Hoffman mainly investigates Neuroscience, Dopamine, Cannabinoid receptor, Internal medicine and Endocrinology. His studies in Neuroscience integrate themes in fields like Synaptic plasticity and Neurotransmission. His research in Dopamine tackles topics such as Glial cell line-derived neurotrophic factor which are related to areas like Midbrain and Medial forebrain bundle.
His Cannabinoid receptor research is multidisciplinary, incorporating perspectives in Cannabinoid, Inhibitory postsynaptic potential and Pharmacology. His study in the field of Disease and Acetylcholine is also linked to topics like Traumatic brain injury and Gene knockdown. His work in Endocrinology addresses issues such as Neurodegeneration, which are connected to fields such as Mitochondrial respiratory chain and Neuroinflammation.
Alexander F. Hoffman mostly deals with Neuroscience, Cannabinoid receptor, Synthetic cannabinoids, Cannabinoid and Internal medicine. His Dopamine and Thalamus study in the realm of Neuroscience connects with subjects such as Context. Alexander F. Hoffman combines subjects such as Gs alpha subunit, G protein and Functional selectivity with his study of Dopamine.
His work carried out in the field of Cannabinoid receptor brings together such families of science as Synaptic plasticity and Pharmacology. As part of the same scientific family, Alexander F. Hoffman usually focuses on Cannabinoid, concentrating on Endocannabinoid system and intersecting with Biological neural network, Brain stimulation reward, Addiction and Drug. RGS4 is closely connected to Endocrinology in his research, which is encompassed under the umbrella topic of Internal medicine.
Alexander F. Hoffman focuses on Neuroscience, Context, Genetically modified mouse, Gene targeting and Genome editing. The study incorporates disciplines such as Endocannabinoid system and Cannabinoid receptor in addition to Neuroscience. Cannabinoid, Synaptic plasticity, Amygdala, Optogenetics and Stria terminalis are fields of study that intersect with his Context study.
His Genetically modified mouse research covers fields of interest such as Cell biology, Cas9 and Viral vector.
This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.
Glial cell line-derived neurotrophic factor reverses toxin-induced injury to midbrain dopaminergic neurons in vivo.
Barry J. Hoffer;Alex Hoffman;Kate Bowenkamp;Peter Huettl.
Neuroscience Letters (1994)
Mechanisms of cannabinoid inhibition of GABA(A) synaptic transmission in the hippocampus.
Alexander F. Hoffman;Carl R. Lupica.
The Journal of Neuroscience (2000)
Powerful cocaine-like actions of 3,4-methylenedioxypyrovalerone (MDPV), a principal constituent of psychoactive 'bath salts' products.
Michael H Baumann;John S Partilla;Kurt R Lehner;Eric B Thorndike.
Glial Cell Line-Derived Neurotrophic Factor Supports Survival of Injured Midbrain Dopaminergic Neurons
Kathryn E. Bowenkamp;Alexander F. Hoffman;Greg A. Gerhardt;Michael A. Henry.
The Journal of Comparative Neurology (1995)
Glial cell line-derived neurotrophic factor augments midbrain dopaminergic circuits in vivo
John Hudson;Ann Charlotte Granholm;Greg A. Gerhardt;Michael A. Henry.
Brain Research Bulletin (1995)
Marijuana and cannabinoid regulation of brain reward circuits.
Carl R Lupica;Arthur C Riegel;Alexander F Hoffman.
British Journal of Pharmacology (2004)
Single rodent mesohabenular axons release glutamate and GABA
David H Root;Carlos A Mejias-Aponte;Shiliang Zhang;Hui-Ling Wang.
Nature Neuroscience (2014)
Functional tolerance and blockade of long-term depression at synapses in the nucleus accumbens after chronic cannabinoid exposure.
Alexander F. Hoffman;Murat Oz;Tara Caulder;Carl R. Lupica.
The Journal of Neuroscience (2003)
Direct actions of cannabinoids on synaptic transmission in the nucleus accumbens: a comparison with opioids.
Alexander F. Hoffman;Carl R. Lupica.
Journal of Neurophysiology (2001)
Cocaine Drives Aversive Conditioning via Delayed Activation of Dopamine-Responsive Habenular and Midbrain Pathways
Thomas C. Jhou;Cameron H. Good;Courtney S. Rowley;Sheng-ping Xu.
The Journal of Neuroscience (2013)
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