D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Neuroscience D-index 33 Citations 5,016 50 World Ranking 4654 National Ranking 2012

Research.com Recognitions

Awards & Achievements

2007 - Hellman Fellow

Overview

What is he best known for?

The fields of study he is best known for:

  • Dopamine
  • Neurotransmitter
  • Neuron

His scientific interests lie mostly in Neuroscience, Dopamine, Dopaminergic, Nucleus accumbens and Pharmacology. He is interested in GABAergic, which is a branch of Neuroscience. His research in Dopamine is mostly concerned with Striatum.

His Dopaminergic research incorporates elements of Glial cell line-derived neurotrophic factor and Neurotrophic factors. His Nucleus accumbens study combines topics from a wide range of disciplines, such as Cannabinoid and Addiction. His Pharmacology research is multidisciplinary, relying on both Sprague dawley and Organ Culture Technique.

His most cited work include:

  • Glial cell line-derived neurotrophic factor reverses toxin-induced injury to midbrain dopaminergic neurons in vivo. (419 citations)
  • Mechanisms of cannabinoid inhibition of GABA(A) synaptic transmission in the hippocampus. (362 citations)
  • Powerful cocaine-like actions of 3,4-methylenedioxypyrovalerone (MDPV), a principal constituent of psychoactive 'bath salts' products. (292 citations)

What are the main themes of his work throughout his whole career to date?

Alexander F. Hoffman mainly investigates Neuroscience, Dopamine, Cannabinoid receptor, Internal medicine and Endocrinology. His studies in Neuroscience integrate themes in fields like Synaptic plasticity and Neurotransmission. His research in Dopamine tackles topics such as Glial cell line-derived neurotrophic factor which are related to areas like Midbrain and Medial forebrain bundle.

His Cannabinoid receptor research is multidisciplinary, incorporating perspectives in Cannabinoid, Inhibitory postsynaptic potential and Pharmacology. His study in the field of Disease and Acetylcholine is also linked to topics like Traumatic brain injury and Gene knockdown. His work in Endocrinology addresses issues such as Neurodegeneration, which are connected to fields such as Mitochondrial respiratory chain and Neuroinflammation.

He most often published in these fields:

  • Neuroscience (57.14%)
  • Dopamine (41.27%)
  • Cannabinoid receptor (25.40%)

What were the highlights of his more recent work (between 2016-2020)?

  • Neuroscience (57.14%)
  • Cannabinoid receptor (25.40%)
  • Synthetic cannabinoids (6.35%)

In recent papers he was focusing on the following fields of study:

Alexander F. Hoffman mostly deals with Neuroscience, Cannabinoid receptor, Synthetic cannabinoids, Cannabinoid and Internal medicine. His Dopamine and Thalamus study in the realm of Neuroscience connects with subjects such as Context. Alexander F. Hoffman combines subjects such as Gs alpha subunit, G protein and Functional selectivity with his study of Dopamine.

His work carried out in the field of Cannabinoid receptor brings together such families of science as Synaptic plasticity and Pharmacology. As part of the same scientific family, Alexander F. Hoffman usually focuses on Cannabinoid, concentrating on Endocannabinoid system and intersecting with Biological neural network, Brain stimulation reward, Addiction and Drug. RGS4 is closely connected to Endocrinology in his research, which is encompassed under the umbrella topic of Internal medicine.

Between 2016 and 2020, his most popular works were:

  • Optogenetic silencing of a corticotropin-releasing factor pathway from the central amygdala to the bed nucleus of the stria terminalis disrupts sustained fear. (51 citations)
  • Cannabinoids as hippocampal network administrators. (33 citations)
  • Neuron-Specific Genome Modification in the Adult Rat Brain Using CRISPR-Cas9 Transgenic Rats. (25 citations)

In his most recent research, the most cited papers focused on:

  • Dopamine
  • Neurotransmitter
  • Neuron

Alexander F. Hoffman focuses on Neuroscience, Context, Genetically modified mouse, Gene targeting and Genome editing. The study incorporates disciplines such as Endocannabinoid system and Cannabinoid receptor in addition to Neuroscience. Cannabinoid, Synaptic plasticity, Amygdala, Optogenetics and Stria terminalis are fields of study that intersect with his Context study.

His Genetically modified mouse research covers fields of interest such as Cell biology, Cas9 and Viral vector.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Glial cell line-derived neurotrophic factor reverses toxin-induced injury to midbrain dopaminergic neurons in vivo.

Barry J. Hoffer;Alex Hoffman;Kate Bowenkamp;Peter Huettl.
Neuroscience Letters (1994)

505 Citations

Mechanisms of cannabinoid inhibition of GABA(A) synaptic transmission in the hippocampus.

Alexander F. Hoffman;Carl R. Lupica.
The Journal of Neuroscience (2000)

463 Citations

Powerful cocaine-like actions of 3,4-methylenedioxypyrovalerone (MDPV), a principal constituent of psychoactive 'bath salts' products.

Michael H Baumann;John S Partilla;Kurt R Lehner;Eric B Thorndike.
Neuropsychopharmacology (2013)

393 Citations

Glial Cell Line-Derived Neurotrophic Factor Supports Survival of Injured Midbrain Dopaminergic Neurons

Kathryn E. Bowenkamp;Alexander F. Hoffman;Greg A. Gerhardt;Michael A. Henry.
The Journal of Comparative Neurology (1995)

341 Citations

Glial cell line-derived neurotrophic factor augments midbrain dopaminergic circuits in vivo

John Hudson;Ann Charlotte Granholm;Greg A. Gerhardt;Michael A. Henry.
Brain Research Bulletin (1995)

286 Citations

Marijuana and cannabinoid regulation of brain reward circuits.

Carl R Lupica;Arthur C Riegel;Alexander F Hoffman.
British Journal of Pharmacology (2004)

274 Citations

Single rodent mesohabenular axons release glutamate and GABA

David H Root;Carlos A Mejias-Aponte;Shiliang Zhang;Hui-Ling Wang.
Nature Neuroscience (2014)

222 Citations

Functional tolerance and blockade of long-term depression at synapses in the nucleus accumbens after chronic cannabinoid exposure.

Alexander F. Hoffman;Murat Oz;Tara Caulder;Carl R. Lupica.
The Journal of Neuroscience (2003)

214 Citations

Direct actions of cannabinoids on synaptic transmission in the nucleus accumbens: a comparison with opioids.

Alexander F. Hoffman;Carl R. Lupica.
Journal of Neurophysiology (2001)

209 Citations

Cocaine Drives Aversive Conditioning via Delayed Activation of Dopamine-Responsive Habenular and Midbrain Pathways

Thomas C. Jhou;Cameron H. Good;Courtney S. Rowley;Sheng-ping Xu.
The Journal of Neuroscience (2013)

186 Citations

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