World's Best Scientists 2026 revealed!

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Neuroscience

D-Index
77
Citations
17338
World Ranking
1874
National Ranking
896

Medicine

D-Index
77
Citations
17338
World Ranking
18576
National Ranking
9255

Overview

Don M. Gash is affiliated with the University of Kentucky in the United States. Their research predominantly spans the fields of neuroscience and medicine, with a specific focus on nerve injury and regeneration, neurological disorders, and treatments. Their work intersects closely with several subfields such as cellular and molecular neuroscience, neurology, cognitive neuroscience, developmental neuroscience, and radiology, nuclear medicine, and imaging.

The scientist's recent publications cover a range of topics primarily related to Parkinson's disease and neurosurgical methodologies. Notable papers include:

  • GDNF clinical trials for Parkinson's disease: a critical human dimension, 2020, Cell and Tissue Research
  • GDNF and Parkinson's Disease: Where Next? A Summary from a Recent Workshop, 2020, Journal of Parkinson s Disease
  • Surgical methodology and protocols for preventing implanted cerebral catheters from becoming obstructed during and after neurosurgery, 2020, Journal of Neuroscience Methods
  • Comparative Studies of Continuous Versus Pulsatile Delivery of a Novel Mammalian Cell-Derived Variant of GDNF (GDNFv) into the Rhesus Macaque Striatum, 2024, Medical Research Archives

Among the frequent co-authors working alongside Don M. Gash are:

  • Greg A. Gerhardt
  • Jorge E. Quintero
  • Yi Ai
  • Richard Grondin
  • Roger A. Barker

Don M. Gash has published in multiple venues, reflecting the interdisciplinary nature of their work. These venues include:

  • Journal of Parkinson s Disease
  • Cell and Tissue Research
  • Journal of Neuroscience Methods
  • Medical Research Archives

The scientist's research topics coalesce around several main themes that support their inquiries into neurological health and disease mechanisms. These main topics are:

  • Nerve injury and regeneration
  • Autism Spectrum Disorder Research
  • Neurogenesis and neuroplasticity mechanisms
  • Neurological disorders and treatments
  • Parkinson's Disease Mechanisms and Treatments
  • Cerebrospinal fluid and hydrocephalus
  • Advanced MRI Techniques and Applications

Through work focused on both foundational neuroscience and clinical applications, Don M. Gash contributes to understanding diseases such as Parkinson's and advancing surgical methods to improve outcomes for neurological patients.

Best Publications

  • Functional recovery in parkinsonian monkeys treated with GDNF.

    D M Gash;Z Zhang;A Ovadia;W A Cass

  • Improvement of bilateral motor functions in patients with Parkinson disease through the unilateral intraputaminal infusion of glial cell line—derived neurotrophic factor

    John T. Slevin;Greg A. Gerhardt;Charles D. Smith;Don M. Gash

  • GDNF protects nigral dopamine neurons against 6-hydroxydopamine in vivo

    Cecilia M. Kearns;Don M. Gash

  • Caloric restriction increases neurotrophic factor levels and attenuates neurochemical and behavioral deficits in a primate model of Parkinson's disease

    Navin Maswood;Jennifer Young;Edward Tilmont;Zhiming Zhang

  • Adrenal medulla grafts enhance recovery of striatal dopaminergic fibers

    Martha C. Bohn;Lisa Cupit;Frederick Marciano;Don M. Gash

  • Chronic, controlled GDNF infusion promotes structural and functional recovery in advanced parkinsonian monkeys

    Richard Grondin;Zhiming Zhang;Ai Yi;Wayne A. Cass

  • Principal component analysis of the dynamic response measured by fMRI: a generalized linear systems framework.

    Anders H. Andersen;Don M. Gash;Malcolm J. Avison

  • The AMPA receptor antagonist NBQX has antiparkinsonian effects in monoamine-depleted rats and MPTP-treated monkeys.

    T Klockgether;L Turski;T Honoré;Z M Zhang

  • Critical decline in fine motor hand movements in human aging

    C.D. Smith;G.H. Umberger;E.L. Manning;J.T. Slevin

  • Point source concentration of GDNF may explain failure of phase II clinical trial.

    Michael Francis Salvatore;Yi Ai;Brent Fischer;Amanda M. Zhang

  • Trichloroethylene: Parkinsonism and complex 1 mitochondrial neurotoxicity.

    Don M. Gash;Kathryn Rutland;Naomi L. Hudson;Patrick G. Sullivan

  • Functional development of grafted vasopressin neurons

    Don Gash;John R. Sladek;Celia D. Sladek

  • Adrenal medullary autografts into the basal ganglia of Cebus monkeys: injury-induced regeneration.

    Massimo S. Fiandaca;Jeffrey H. Kordower;John T. Hansen;Shou-Shu Jiao

  • Nerve growth factor receptor immunoreactivity in the nonhuman primate (Cebus apella): distribution, morphology, and colocalization with cholinergic enzymes.

    Jeffrey H. Kordower;Raymond T. Bartus;Mark Bothwell;Gina Schatteman

  • Disruption of the blood-brain barrier as the primary effect of CNS irradiation.

    P. Rubin;D.M. Gash;J.T. Hansen;D.F. Nelson

  • Neuroprotective and neurorestorative properties of GDNF.

    Don M. Gash;Zhiming Zhang;Greg Gerhardt

  • Antiparkinsonian effects of remacemide hydrochloride, a glutamate antagonist, in rodent and primate models of Parkinson's disease

    J. T. Greenamyre;R. V. Eller;Zhiming Zhang;A. Ovadia

  • Unilateral intraputamenal glial cell line–derived neurotrophic factor in patients with Parkinson disease: response to 1 year of treatment and 1 year of withdrawal

    John T Slevin;Don M Gash;Charles D Smith;Greg A Gerhardt

  • GDNF Protection against 6-OHDA: Time Dependence and Requirement for Protein Synthesis

    Cecilia M. Kearns;Wayne A. Cass;Kyle Smoot;Richard Kryscio

  • Glial cell line-derived neurotrophic factor (GDNF): a drug candidate for the treatment of Parkinson’s disease

    R. Grondin;Don M. Gash

  • Vasopressin : principles and properties

    Don M. Gash;Gerard J. Boer

Frequent Co-Authors

Greg A. Gerhardt
Greg A. Gerhardt University of Kentucky
Zhiming Zhang
Zhiming Zhang University of Kentucky
Richard Grondin
Richard Grondin University of Kentucky
Wayne A. Cass
Wayne A. Cass University of Kentucky
John R. Sladek
John R. Sladek University of Colorado Denver
Guoying Bing
Guoying Bing University of Kentucky
Richard J. Kryscio
Richard J. Kryscio University of Kentucky
Charles D. Smith
Charles D. Smith University of Kentucky
John T. Slevin
John T. Slevin University of Kentucky
James P. Herman
James P. Herman University of Cincinnati

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