World's Best Scientists 2026 revealed!

D-Index & Metrics

Medicine

D-Index
102
Citations
33203
World Ranking
7749
National Ranking
4036

Charles D. Smith publication distribution in Medicine in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Medicine in 2026. The highlighted bar marks where Charles D. Smith sits on this spectrum.

101–120 publications: 5 scientists 121–140 publications: 26 scientists 141–160 publications: 73 scientists 161–180 publications: 155 scientists 181–200 publications: 230 scientists 201–220 publications: 363 scientists 221–240 publications: 487 scientists 241–260 publications: 545 scientists 261–280 publications: 722 scientists 281–300 publications: 768 scientists 301–320 publications: 834 scientists 321–340 publications: 895 scientists 341–360 publications: 922 scientists 361–380 publications: 838 scientists 381–400 publications: 861 scientists 401–420 publications: 918 scientists 421–440 publications: 806 scientists 441–460 publications: 771 scientists 461–480 publications: 751 scientists 481–500 publications: 713 scientists 501–520 publications: 617 scientists 521–540 publications: 611 scientists 541–560 publications: 537 scientists 561–580 publications: 504 scientists 581–600 publications: 509 scientists 601–620 publications: 396 scientists 621–640 publications: 386 scientists 641–660 publications: 371 scientists 661–680 publications: 340 scientists 681–700 publications: 336 scientists 701–720 publications: 307 scientists 721–740 publications: 259 scientists 741–760 publications: 230 scientists 761–780 publications: 228 scientists 781–800 publications: 217 scientists 801–820 publications: 204 scientists 821–840 publications: 186 scientists 841–860 publications: 177 scientists 861–880 publications: 155 scientists 881–900 publications: 139 scientists 901–920 publications: 145 scientists 921–940 publications: 116 scientists 941–960 publications: 133 scientists 961–980 publications: 91 scientists 981–1,000 publications: 96 scientists 1,001–1,020 publications: 77 scientists 1,021–1,040 publications: 70 scientists 1,041–1,060 publications: 63 scientists 1,061–1,080 publications: 77 scientists 1,081–1,100 publications: 49 scientists 1,101–1,120 publications: 54 scientists 1,121–1,140 publications: 49 scientists 1,141–1,160 publications: 51 scientists 1,161–1,180 publications: 35 scientists 1,181–1,200 publications: 39 scientists 1,201–1,220 publications: 26 scientists 1,221–1,240 publications: 37 scientists 1,241–1,260 publications: 36 scientists 1,261–1,280 publications: 27 scientists 1,281–1,300 publications: 32 scientists 1,301–1,320 publications: 28 scientists 1,321–1,340 publications: 17 scientists 1,341–1,360 publications: 30 scientists 1,361–1,380 publications: 28 scientists 1,381–1,400 publications: 17 scientists 1,401–1,420 publications: 21 scientists 1,421–1,440 publications: 15 scientists 1,441–1,460 publications: 12 scientists 1,461–1,480 publications: 12 scientists 1,481–1,500 publications: 18 scientists 1,501–1,520 publications: 14 scientists 1,521–1,540 publications: 17 scientists 1,541–1,560 publications: 15 scientists 1,561–1,580 publications: 6 scientists 1,581–1,600 publications: 2 scientists 1,601–1,620 publications: 12 scientists 1,621–1,640 publications: 11 scientists 1,641–1,660 publications: 8 scientists 1,661–1,680 publications: 5 scientists 1,681–1,700 publications: 5 scientists 1,701–1,720 publications: 10 scientists 1,721–1,740 publications: 12 scientists 1,741–1,760 publications: 14 scientists 1,761–1,780 publications: 6 scientists 1,781–1,795 publications: 5 scientists 1,796+ publications: 100 scientists
101 publications 1,796+

This scientist: 420 publications — 43rd percentile

43% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,796 publications or more.

Charles D. Smith D-index placement in Medicine in 2026

The chart shows the D-index (discipline H-index) distribution of Medicine scientists ranked by Research.com in 2026. The highlighted bar marks where Charles D. Smith sits on this spectrum.

70–71 D-Index: 226 scientists 72–73 D-Index: 391 scientists 74–75 D-Index: 574 scientists 76–77 D-Index: 730 scientists 78–79 D-Index: 891 scientists 80–81 D-Index: 972 scientists 82–83 D-Index: 1,027 scientists 84–85 D-Index: 1,003 scientists 86–87 D-Index: 960 scientists 88–89 D-Index: 970 scientists 90–91 D-Index: 922 scientists 92–93 D-Index: 839 scientists 94–95 D-Index: 808 scientists 96–97 D-Index: 779 scientists 98–99 D-Index: 668 scientists 100–101 D-Index: 611 scientists 102–103 D-Index: 630 scientists 104–105 D-Index: 513 scientists 106–107 D-Index: 541 scientists 108–109 D-Index: 445 scientists 110–111 D-Index: 429 scientists 112–113 D-Index: 400 scientists 114–115 D-Index: 393 scientists 116–117 D-Index: 318 scientists 118–119 D-Index: 302 scientists 120–121 D-Index: 287 scientists 122–123 D-Index: 255 scientists 124–125 D-Index: 256 scientists 126–127 D-Index: 252 scientists 128–129 D-Index: 230 scientists 130–131 D-Index: 179 scientists 132–133 D-Index: 168 scientists 134–135 D-Index: 163 scientists 136–137 D-Index: 159 scientists 138–139 D-Index: 134 scientists 140–141 D-Index: 134 scientists 142–143 D-Index: 118 scientists 144–145 D-Index: 109 scientists 146–147 D-Index: 106 scientists 148–149 D-Index: 74 scientists 150–151 D-Index: 79 scientists 152–153 D-Index: 80 scientists 154–155 D-Index: 87 scientists 156–157 D-Index: 57 scientists 158–159 D-Index: 74 scientists 160–161 D-Index: 69 scientists 162–163 D-Index: 60 scientists 164–165 D-Index: 53 scientists 166–167 D-Index: 39 scientists 168–169 D-Index: 42 scientists 170–171 D-Index: 32 scientists 172–173 D-Index: 39 scientists 174–175 D-Index: 40 scientists 176–177 D-Index: 28 scientists 178–179 D-Index: 19 scientists 180–181 D-Index: 23 scientists 182–183 D-Index: 31 scientists 184–185 D-Index: 18 scientists 186–187 D-Index: 20 scientists 188–189 D-Index: 22 scientists 190–191 D-Index: 13 scientists 192–193 D-Index: 21 scientists 194–195 D-Index: 12 scientists 196–197 D-Index: 12 scientists 198–199 D-Index: 14 scientists 200–201 D-Index: 15 scientists 202–203 D-Index: 13 scientists 204–205 D-Index: 10 scientists 206–207 D-Index: 8 scientists 208–209 D-Index: 4 scientists 210–211 D-Index: 12 scientists 212–213 D-Index: 11 scientists 214–215 D-Index: 10 scientists 216 D-Index: 4 scientists 217+ D-Index: 98 scientists
70 D-Index 217+

This scientist: 102 D-Index — 63rd percentile

63% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 217 D-Index or more.

Research.com Recognitions

  • 1964 - Fellow of the Royal Society of Canada Academy of Science

Overview

Charles D. Smith is affiliated with the University of Kentucky in the United States. Their research primarily spans the fields of Biochemistry, Genetics and Molecular Biology, as well as Medicine, with a notable focus on Molecular Biology and Cancer Research within these disciplines. The work also addresses several specialized subfields such as Immunology, Epidemiology, and Infectious Diseases.

The scientist's recent work has concentrated on areas including:

  • Sphingolipid Metabolism and Signaling
  • Cancer, Hypoxia, and Metabolism
  • Autophagy in Disease and Therapy
  • Phagocytosis and Immune Regulation
  • Cell death mechanisms and regulation
  • COVID-19 Clinical Research Studies
  • Radioactive element chemistry and processing

Charles D. Smith has contributed to multiple publications, often collaborating with frequent co-authors Lynn W. Maines and Staci N. Keller, among others including Randy S. Schrecengost, Cecelia L. Green, and Ryan A. Smith.

The scientist's notable recent papers include:

  • Recent Progress in the Development of Opaganib for the Treatment of Covid-19, 2022, Drug Design Development and Therapy
  • Support loading effects on the performance of an extraction chromatographic resin: Toward improved separation of trivalent lanthanides, 2020, Talanta
  • Opaganib (ABC294640) Induces Immunogenic Tumor Cell Death and Enhances Checkpoint Antibody Therapy, 2023, International Journal of Molecular Sciences
  • Analysis of selective target engagement by small-molecule sphingosine kinase inhibitors using the Cellular Thermal Shift Assay (CETSA), 2020, Cancer Biology & Therapy
  • Opaganib Protects against Radiation Toxicity: Implications for Homeland Security and Antitumor Radiotherapy, 2022, International Journal of Molecular Sciences

Charles D. Smith publishes frequently in the following scientific venues:

  • International Journal of Molecular Sciences
  • Drug Design Development and Therapy
  • Talanta
  • Cancer Biology & Therapy
  • International Journal of Nephrology and Renovascular Disease

An award associated with Charles D. Smith is the Fellowship of the Royal Society of Canada granted in 1964, acknowledged by the Academy of Science.

Best Publications

  • Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease.

    Adam C. Naj;Gyungah Jun;Gary W. Beecham;Li-San Wang

  • Early role of vascular dysregulation on late-onset Alzheimer’s disease based on multifactorial data-driven analysis

    Y. Iturria-Medina;R. C. Sotero;P. J. Toussaint;J. M. Mateos-Pérez

  • Discovery and evaluation of inhibitors of human sphingosine kinase.

    Kevin J. French;Randy S. Schrecengost;Brian D. Lee;Yan Zhuang

  • Neuropathology of nondemented aging: Presumptive evidence for preclinical Alzheimer disease

    Joseph L. Price;Daniel W. McKeel;Virginia D. Buckles;Catherine M. Roe

  • Neuropathologic substrate of mild cognitive impairment.

    William R. Markesbery;Frederick A. Schmitt;Richard J. Kryscio;Daron G. Davis

  • Neural substrates of facial emotion processing using fMRI.

    Marilyn L. Kesler;West;Anders H. Andersen;Charles D. Smith

  • Serum antibodies to periodontal pathogens are a risk factor for Alzheimer’s disease

    Pamela Sparks Stein;Michelle J. Steffen;Charles Smith;Gregory Jicha

  • Mutant V599EB-Raf regulates growth and vascular development of malignant melanoma tumors.

    Arati Sharma;Nishit R. Trivedi;Melissa A. Zimmerman;David A. Tuveson

  • Alzheimer’s disease is not “brain aging”: neuropathological, genetic, and epidemiological human studies

    Peter T. Nelson;Elizabeth Head;Frederick A. Schmitt;Paulina R. Davis

  • Pharmacology and Antitumor Activity of ABC294640, a Selective Inhibitor of Sphingosine Kinase-2

    Kevin J. French;Yan Zhuang;Lynn W. Maines;Peng Gao

  • Antitumor activity of sphingosine kinase inhibitors

    Kevin J. French;John J. Upson;Staci N. Keller;Yan Zhuang

  • Basal forebrain degeneration precedes and predicts the cortical spread of Alzheimer's pathology.

    Taylor W. Schmitz;R. Nathan Spreng;Michael W. Weiner;Paul Aisen

  • Cryptophycin: A New Antimicrotubule Agent Active against Drug-resistant Cells

    Charles D. Smith;Xinqun Zhang;Susan L. Mooberry;Gregory M.L. Patterson

  • Reduction of TRAIL-Induced Mcl-1 and cIAP2 by c-Myc or Sorafenib Sensitizes Resistant Human Cancer Cells to TRAIL-Induced Death

    M. Stacey Ricci;Seok Hyun Kim;Kazuhiro Ogi;John P. Plastaras

  • Low sensitivity in clinical diagnoses of dementia with Lewy bodies

    Peter T. Nelson;Gregory A. Jicha;Richard J. Kryscio;Erin L. Abner

  • Hippocampal sclerosis in advanced age: clinical and pathological features

    Peter T. Nelson;Frederick A. Schmitt;Yushun Lin;Erin L. Abner

  • Trichloroethylene: Parkinsonism and complex 1 mitochondrial neurotoxicity.

    Don M. Gash;Kathryn Rutland;Naomi L. Hudson;Patrick G. Sullivan

  • Novel ubiquitin neuropathology in frontotemporal dementia with valosin-containing protein gene mutations.

    Mark S. Forman;Ian R. Mackenzie;Nigel J. Cairns;Eric Swanson

  • Evidence for a role of the rare p.A152T variant in MAPT in increasing the risk for FTD-spectrum and Alzheimer's diseases

    Giovanni Coppola;Subashchandrabose Chinnathambi;Jason Ji Yong Lee;Beth A. Dombroski

  • Altered brain activation in cognitively intact individuals at high risk for Alzheimer’s disease

    C.D. Smith;A.H. Andersen;R.J. Kryscio;F.A. Schmitt

Frequent Co-Authors

Gregory A. Jicha
Gregory A. Jicha University of Kentucky
Frederick A. Schmitt
Frederick A. Schmitt University of Kentucky
Richard J. Kryscio
Richard J. Kryscio University of Kentucky
Peter T. Nelson
Peter T. Nelson University of Kentucky
William R. Markesbery
William R. Markesbery University of Kentucky
Linda J. Van Eldik
Linda J. Van Eldik University of Kentucky
Brian T. Gold
Brian T. Gold University of Kentucky
Wafik S. El-Deiry
Wafik S. El-Deiry Brown University
Robert C. Green
Robert C. Green Brigham and Women's Hospital
Andrew S. Kraft
Andrew S. Kraft University of Arizona

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