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Emmanuel Van Obberghen

Emmanuel Van Obberghen

D-Index & Metrics

Biology and Biochemistry

D-Index
74
Citations
17826
World Ranking
5656
National Ranking
159

Overview

Emmanuel Van Obberghen is affiliated with Université Côte d'Azur in France. Their research spans multiple disciplines primarily within biochemistry, genetics, molecular biology, and medicine. They have contributed to fields including molecular biology, immunology and allergy, oncology, and cell biology.

The scientist's recent research topics focus on areas such as:

  • Cell Adhesion Molecules Research
  • RNA Research and Splicing
  • Cellular Mechanics and Interactions
  • Protease and Inhibitor Mechanisms
  • Immune cells in cancer
  • Cancer Cells and Metastasis
  • Fibroblast Growth Factor Research

Their work has been published in various scientific venues, most frequently appearing in:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Frontiers in Oncology
  • Cancer Immunology Research
  • Frontiers in Immunology
  • Matrix Biology

Some of the recent papers authored by Emmanuel Van Obberghen or closely associated include:

  • "Shaping Up the Tumor Microenvironment With Cellular Fibronectin," 2020, Frontiers in Oncology
  • "Tenascin-C Orchestrates an Immune-Suppressive Tumor Microenvironment in Oral Squamous Cell Carcinoma," 2020, Cancer Immunology Research
  • "High Dimensional Imaging Mass Cytometry Panel to Visualize the Tumor Immune Microenvironment Contexture," 2021, Frontiers in Immunology
  • "The alternative matrisome: Alternative splicing of ECM proteins in development, homeostasis and tumor progression," 2022, Matrix Biology
  • "Fibronectin Extra Domains tune cellular responses and confer topographically distinct features to fibril networks," 2021, Journal of Cell Science

Frequent coauthors collaborating with Emmanuel Van Obberghen include:

  • Georgios Efthymiou
  • Zeinab Rekad
  • Delphine Ciais
  • Michael W. Ruff
  • Agata Radwańska

The scientist's interdisciplinary approach integrates biochemistry and molecular biology with immunology and oncology, with significant emphasis on tumor microenvironments, cellular adhesion mechanisms, and immune response in cancer settings. Their contributions reflect a focus on both basic and applied biomedical research, particularly addressing the complexities of cancer progression and immune modulation at the cellular and molecular levels.

Best Publications

  • Insulin stimulates hypoxia-inducible factor 1 through a phosphatidylinositol 3-kinase/target of rapamycin-dependent signaling pathway.

    Caroline Treins;Sophie Giorgetti-Peraldi;Joseph Murdaca;Gregg L. Semenza

  • SOCS-3 is an insulin-induced negative regulator of insulin signaling.

    Brice Emanuelli;Pascal Peraldi;Chantal Filloux;Dominique Sawka-Verhelle

  • SOCS-3 inhibits insulin signaling and is up-regulated in response to tumor necrosis factor-alpha in the adipose tissue of obese mice.

    B Emanuelli;P Peraldi;C Filloux;C Chavey

  • miR-375 Targets 3′-Phosphoinositide–Dependent Protein Kinase-1 and Regulates Glucose-Induced Biological Responses in Pancreatic β-Cells

    Abdelfattah El Ouaamari;Nadine Baroukh;Geert A. Martens;Patricia Lebrun

  • Matrix Metalloproteinases Are Differentially Expressed in Adipose Tissue during Obesity and Modulate Adipocyte Differentiation

    Carine Chavey;Bernard Mari;Marie-Noëlle Monthouel;Stéphanie Bonnafous

  • Malnutrition is an independent factor associated with nosocomial infections

    Stéphane M. Schneider;Patricia Veyres;Xavier Pivot;Anne-Marie Soummer

  • MicroRNA-124a Regulates Foxa2 Expression and Intracellular Signaling in Pancreatic β-Cell Lines

    Nadine Baroukh;Magalie A. Ravier;Merewyn K. Loder;Elaine V. Hill

  • Mechanism of protein kinase B activation by cyclic AMP-dependent protein kinase.

    Nathalie Filippa;Carol L. Sable;Chantal Filloux;Brian Hemmings

  • Potential role of protein kinase B in glucose transporter 4 translocation in adipocytes.

    J F Tanti;S Grillo;T Grémeaux;P J Coffer

  • Phosphorylation of Insulin Receptor Substrate-1 on Multiple Serine Residues, 612, 632, 662, and 731, Modulates Insulin Action

    Isabelle Mothe;Emmanuel Van Obberghen

  • Methylglyoxal Impairs the Insulin Signaling Pathways Independently of the Formation of Intracellular Reactive Oxygen Species

    Audrey Riboulet-Chavey;Anne Pierron;Isabelle Durand;Joseph Murdaca

  • Glucose, Other Secretagogues, and Nerve Growth Factor Stimulate Mitogen-activated Protein Kinase in the Insulin-secreting β-Cell Line, INS-1

    Morten Frödin;Nobuo Sekine;Enrique Roche;Chantal Filloux

  • Regulation of Vascular Endothelial Growth Factor Expression by Advanced Glycation End Products

    Caroline Treins;Sophie Giorgetti-Peraldi;Joseph Murdaca;Emmanuel Van Obberghen

  • Insulin and Insulin-like Growth Factor-I Induce Vascular Endothelial Growth Factor mRNA Expression via Different Signaling Pathways

    Claudia Miele;Justin J. Rochford;Nathalie Filippa;Sophie Giorgetti-Peraldi

  • MicroRNAs and metabolism crosstalk in energy homeostasis.

    Olivier Dumortier;Olivier Dumortier;Olivier Dumortier;Charlotte Hinault;Emmanuel Van Obberghen

  • cAMP stimulates protein kinase B in a Wortmannin-insensitive manner.

    Carol L Sable;Nathalie Filippa;Brian Hemmings;Emmanuel Van Obberghen

  • Insulin receptor substrate-2 binds to the insulin receptor through its phosphotyrosine-binding domain and through a newly identified domain comprising amino acids 591-786.

    Dominique Sawka-Verhelle;Sophie Tartare-Deckert;Morris F. White;Emmanuel Van Obberghen

  • Insulin receptor tyrosine kinase is defective in skeletal muscle of insulin-resistant obese mice.

    Yannick Le Marchand-Brustel;Thierry Grémeaux;Robert Ballotti;Emmanuel Van Obberghen

  • Overexpression of a Constitutively Active Form of Phosphatidylinositol 3-Kinase Is Sufficient to Promote Glut 4 Translocation in Adipocytes

    Jean-François Tanti;Thierry Grémeaux;Sophie Grillo;Véronique Calleja

  • Effect of phosphoinositide-dependent kinase 1 on protein kinase B translocation and its subsequent activation.

    Nathalie Filippa;Carol L. Sable;Brian A. Hemmings;Emmanuel Van Obberghen

Frequent Co-Authors

Robert Ballotti
Robert Ballotti Université Côte d'Azur
Jean-François Tanti
Jean-François Tanti Université Côte d'Azur
Morris F. White
Morris F. White Boston Children's Hospital
Paul Hofman
Paul Hofman Grenoble Alpes University
Brian A. Hemmings
Brian A. Hemmings Friedrich Miescher Institute
Marc Prentki
Marc Prentki University of Montreal
Pietro Formisano
Pietro Formisano University of Naples Federico II
Paul Grimaldi
Paul Grimaldi Université Côte d'Azur
John C. Lawrence
John C. Lawrence University of Virginia
Lelio Orci
Lelio Orci University of Geneva

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