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Biology and Biochemistry

D-Index
62
Citations
16187
World Ranking
10660
National Ranking
101

Overview

Yehiel Zick is affiliated with the Weizmann Institute of Science in Israel. Their research spans multiple fields related to biochemistry, genetics, molecular biology, immunology, and microbiology. The scientist has contributed extensively to the understanding of galectins, cell adhesion molecules, RNA research, and cellular mechanics.

The main areas of study for Yehiel Zick include:

  • Biochemistry, Genetics and Molecular Biology
  • Immunology and Microbiology

Their subfields of study cover:

  • Molecular Biology
  • Immunology
  • Cell Biology
  • Immunology and Allergy
  • Surgery

Key topics in their research work are:

  • Galectins and Cancer Biology
  • Glycosylation and Glycoproteins Research
  • Cell Adhesion Molecules Research
  • Cellular Mechanics and Interactions
  • RNA Research and Splicing
  • RNA modifications and cancer
  • Nuclear Structure and Function

Yehiel Zick has published several papers with notable contributions across a range of journals and venues, including:

  • The Animal Lectin Galectin-8 Promotes Cytokine Expression and Metastatic Tumor Growth in Mice, 2020, Scientific Reports
  • Differential cellular responses to adhesive interactions with galectin-8- and fibronectin-coated substrates, 2021, Journal of Cell Science
  • Rational Design and Synthesis of Methyl-β-d-galactomalonyl Phenyl Esters as Potent Galectin-8N Antagonists, 2020, Journal of Medicinal Chemistry
  • TM7SF3 controls TEAD1 splicing to prevent MASH-induced liver fibrosis, 2024, Cell Metabolism
  • A seven-transmembrane protein-TM7SF3, resides in nuclear speckles and regulates alternative splicing, 2022, iScience

Frequent coauthors in their research include:

  • Yaron Vinik
  • Roi Isaac
  • Hadas Shatz-Azoulay
  • Nicholas J. G. Webster
  • Sima Lev

Yehiel Zick has a consistent presence in publication venues such as bioRxiv (Cold Spring Harbor Laboratory), where they have published three papers, as well as contributions to Cell Metabolism, Scientific Reports, Journal of Cell Science, and Journal of Medicinal Chemistry.

Best Publications

  • Insulin Resistance and Hyperinsulinemia Is hyperinsulinemia the cart or the horse

    Michael H. Shanik;Yuping Xu;Jan Škrha;Rachel Dankner

  • A molecular basis for insulin resistance. Elevated serine/threonine phosphorylation of IRS-1 and IRS-2 inhibits their binding to the juxtamembrane region of the insulin receptor and impairs their ability to undergo insulin-induced tyrosine phosphorylation

    Keren Paz;Rina Hemi;Derek LeRoith;Avraham Karasik

  • Phosphorylation of IRS proteins, insulin action, and insulin resistance

    Sigalit Boura-Halfon;Yehiel Zick

  • The insulinomimetic agents H2O2 and vanadate stimulate protein tyrosine phosphorylation in intact cells.

    D Heffetz;I Bushkin;R Dror;Y Zick

  • Recent advances in our understanding of insulin action and insulin resistance.

    Derek Le Roith;Yehiel Zick

  • Ser/Thr phosphorylation of IRS proteins: a molecular basis for insulin resistance

    Yehiel Zick

  • Insulin resistance: a phosphorylation-based uncoupling of insulin signaling

    Yehiel Zick

  • Selective inhibition of protein tyrosine phosphatase activities by H2O2 and vanadate in vitro.

    Dalit Hecht;Yehiel Zick

  • The effect of tyrosine-specific protein phosphorylation on the assembly of adherens-type junctions.

    T Volberg;Y Zick;R Dror;I Sabanay

  • Galectin-8 binding to integrins inhibits cell adhesion and induces apoptosis

    Yaron R. Hadari;Rinat Arbel-Goren;Yifat Levy;Avraham Amsterdam

  • Phosphorylation of Insulin Receptor Substrate-1 (IRS-1) by Protein Kinase B Positively Regulates IRS-1 Function

    Keren Paz;Yan-Fang Liu;Hagai Shorer;Rina Hemi

  • Role of galectin-8 as a modulator of cell adhesion and cell growth.

    Yehiel Zick;Miriam Eisenstein;Rinat A. Goren;Yaron R. Hadari

  • Insulin Stimulates PKCζ-mediated Phosphorylation of Insulin Receptor Substrate-1 (IRS-1) A SELF-ATTENUATED MECHANISM TO NEGATIVELY REGULATE THE FUNCTION OF IRS PROTEINS

    Yan-Fang Liu;Keren Paz;Avia Herschkovitz;Addy Alt

  • Galectin-8 A NEW RAT LECTIN, RELATED TO GALECTIN-4

    Yaron R. Hadari;Keren Paz;Roi Dekel;Tomislav Mestrovic

  • Galectin-8 Functions as a Matricellular Modulator of Cell Adhesion

    Yifat Levy;Rinat Arbel-Goren;Yaron R. Hadari;Sharon Eshhar

  • Modulation of intercellular adherens-type junctions and tyrosine phosphorylation of their components in RSV-transformed cultured chick lens cells.

    T Volberg;B Geiger;R Dror;Y Zick

  • Insulin Stimulates PKCζ-mediated Phosphorylation of Insulin Receptor Substrate-1 (IRS-1)

    Yan-Fang Liu;Keren Paz;Avia Herschkovitz;Addy Alt

  • Benign metastasizing leiomyoma of the uterus: documentation of clinical, immunohistochemical and lectin-histochemical data of ten cases

    Klaus Kayser;Stefan Zink;Thomas Schneider;Hendrik Dienemann

  • Defect in Phosphorylation of Insulin Receptors in Cells from an Insulin-Resistant Patient with Normal Insulin Binding

    George Grunberger;Yehiel Zick;Phillip Gorden

  • Molecular basis for insulin resistance: elevated serine/threonine phosphorylation of IRS-1 and IRS-2 inhibits their binding to the juxtamembrane region of the insulin receptor and impairs their ability to undergo insulin-induced tyrosine phosphorylation

    Keren Paz;Rina Hemi;Derek LeRoith;Avraham Karasik

Frequent Co-Authors

Derek LeRoith
Derek LeRoith Icahn School of Medicine at Mount Sinai
Hans-Joachim Gabius
Hans-Joachim Gabius Ludwig-Maximilians-Universität München
Herbert Kaltner
Herbert Kaltner Ludwig-Maximilians-Universität München
Jesse Roth
Jesse Roth National Institutes of Health
Benjamin Geiger
Benjamin Geiger Weizmann Institute of Science
Simeon I. Taylor
Simeon I. Taylor National Institutes of Health
Phillip Gorden
Phillip Gorden National Institutes of Health
Robert Kiss
Robert Kiss Université Libre de Bruxelles
Sabine André
Sabine André Ludwig-Maximilians-Universität München
Alexander D. Bershadsky
Alexander D. Bershadsky National University of Singapore

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