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Biology and Biochemistry

D-Index
59
Citations
14070
World Ranking
12427
National Ranking
886

Overview

Sascha Sauer is affiliated with the Max Delbrück Center for Molecular Medicine in Germany. Their research spans multiple disciplines, mainly within Biochemistry, Genetics and Molecular Biology, and Medicine. The scientist has contributed extensively to Molecular Biology, Immunology, Cancer Research, Surgery, and Infectious Diseases.

The work of Sascha Sauer often focuses on themes such as Single-cell and spatial transcriptomics, Cancer, Hypoxia, and Metabolism, Adrenal and Paraganglionic Tumors, Epigenetics and DNA Methylation, Immune cells in cancer, Immune Cell Function and Interaction, and Hormonal Regulation and Hypertension.

Recent publications include:

  • Single-cell sequencing of human midbrain reveals glial activation and a Parkinson-specific neuronal state, 2021, Brain
  • Benchmarking single-cell RNA-sequencing protocols for cell atlas projects, 2020, Nature Biotechnology
  • Self-Organizing 3D Human Trunk Neuromuscular Organoids, 2020, Cell stem cell
  • Resolving Fates and Single-Cell Transcriptomes of Hematopoietic Stem Cell Clones by PolyloxExpress Barcoding, 2020, Cell stem cell
  • Maximizing transcription of nucleic acids with efficient T7 promoters, 2020, Communications Biology

Frequent co-authors include:

  • Cornelius Fischer
  • Ramón Vidal
  • Barbara Altieri
  • Silviu Sbiera
  • Martin Faßnacht

Sascha Sauer's publications often appear in venues such as bioRxiv (Cold Spring Harbor Laboratory), Endocrine Abstracts, Cell stem cell, Nature Communications, and Communications Biology.

Best Publications

  • Perturbation-response genes reveal signaling footprints in cancer gene expression.

    Michael Schubert;Bertram Klinger;Martina Klünemann;Martina Klünemann;Anja Sieber;Anja Sieber

  • Mass spectrometry tools for the classification and identification of bacteria

    Sascha Sauer;Magdalena Kliem

  • Classification and identification of bacteria by mass spectrometry and computational analysis.

    Sascha Sauer;Anja Freiwald;Thomas Maier;Michael Kube

  • Phylogenetic classification and identification of bacteria by mass spectrometry

    Anja Freiwald;Sascha Sauer

  • Benchmarking Single-Cell RNA Sequencing Protocols for Cell Atlas Projects

    Elisabetta Mereu;Atefeh Lafzi;Catia Moutinho;Christoph Ziegenhain

  • Polylox barcoding reveals haematopoietic stem cell fates realized in vivo

    Weike Pei;Thorsten B. Feyerabend;Jens Rössler;Xi Wang

  • Targeted enrichment of genomic DNA regions for next generation sequencing

    Florian Mertes;Abdou ElSharawy;Sascha Sauer;Joop M.L.M. van Helvoort

  • A novel procedure for efficient genotyping of single nucleotide polymorphisms.

    Sascha Sauer;Doris Lechner;Kurt Berlin;Hans Lehrach

  • Extrachromosomal circular DNA drives oncogenic genome remodeling in neuroblastoma

    Richard P. Koche;Elias Rodriguez-Fos;Konstantin Helmsauer;Martin Burkert;Martin Burkert

  • Amorfrutins are potent antidiabetic dietary natural products

    Christopher Weidner;Jens C. de Groot;Aman Prasad;Anja Freiwald

  • Self-Organizing 3D Human Trunk Neuromuscular Organoids

    Jorge-Miguel Faustino Martins;Cornelius Fischer;Alessia Urzi;Ramon Vidal

  • Identification of novel genetic causes of Rett syndrome-like phenotypes

    Fátima Lopes;Mafalda Barbosa;Adam Ameur;Gabriela Soares

  • The Transcription Factor STAT6 Mediates Direct Repression of Inflammatory Enhancers and Limits Activation of Alternatively Polarized Macrophages

    Zsolt Czimmerer;Bence Daniel;Attila Horvath;Dominik Rückerl

  • Deficient methylation and formylation of mt-tRNA Met wobble cytosine in a patient carrying mutations in NSUN3

    Lindsey Van Haute;Sabine Dietmann;Laura Kremer;Shobbir Hussain

  • Characterization of bacterial communities in wastewater with enhanced taxonomic resolution by full-length 16S rRNA sequencing.

    Daniela Numberger;Lars Ganzert;Luca Zoccarato;Kristin Mühldorfer

  • Miniaturization in functional genomics and proteomics

    Sascha Sauer;Bodo M. H. Lange;Johan Gobom;Lajos Nyarsik

  • Identification of novel transcriptional regulators involved in macrophage differentiation and activation in U937 cells

    Young-Sook Baek;Stefan Haas;Holger Hackstein;Gregor Bein

  • The Nuclear Receptor PPARγ Controls Progressive Macrophage Polarization as a Ligand-Insensitive Epigenomic Ratchet of Transcriptional Memory.

    Bence Daniel;Gergely Nagy;Zsolt Czimmerer;Attila Horvath

  • Association mapping reveals gene action and interactions in the determination of flowering time in barley

    Silke Stracke;Silke Stracke;Grit Haseneyer;Grit Haseneyer;Jean-Baptiste Veyrieras;Hartwig H. Geiger

  • Comprehensive gene expression meta-analysis identifies signature genes that distinguish microglia from peripheral monocytes/macrophages in health and glioma

    Verena Haage;Marcus Semtner;Ramon Oliveira Vidal;Daniel Perez Hernandez

Frequent Co-Authors

Laszlo Nagy
Laszlo Nagy University of Debrecen
Hans Lehrach
Hans Lehrach Max Planck Society
Richard Reinhardt
Richard Reinhardt Max Planck Society
Ann-Christine Syvänen
Ann-Christine Syvänen Uppsala University
Frank C. Schroeder
Frank C. Schroeder Boyce Thompson Institute
Ivo Gut
Ivo Gut Centro Nacional de Análisis Genómico
Richard Durbin
Richard Durbin University of Cambridge
Jean-François Deleuze
Jean-François Deleuze University of Paris-Saclay
Aviv Regev
Aviv Regev Genentech
Andre Franke
Andre Franke Kiel University

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