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Jason D. Buenrostro

Jason D. Buenrostro

D-Index & Metrics

Biology and Biochemistry

D-Index
59
Citations
31759
World Ranking
12247
National Ranking
5235

Overview

Jason D. Buenrostro is affiliated with Harvard University in the United States and has a considerable body of research within the field of Biochemistry, Genetics, and Molecular Biology. Their work spans multiple subfields including Molecular Biology, Immunology, Cancer Research, Oncology, and Neurology.

Their research primarily addresses topics such as Single-cell and spatial transcriptomics, Genomics and Chromatin Dynamics, Cancer Genomics and Diagnostics, Epigenetics and DNA Methylation, RNA Research and Splicing, Immune Cell Function and Interaction, and CRISPR and Genetic Engineering.

Jason D. Buenrostro has contributed to several notable papers, including:

  • Chromatin Potential Identified by Shared Single-Cell Profiling of RNA and Chromatin, 2020, Cell
  • Deep learning and alignment of spatially resolved single-cell transcriptomes with Tangram, 2021, Nature Methods
  • The neutrotime transcriptional signature defines a single continuum of neutrophils across biological compartments, 2021, Nature Communications
  • Massively parallel single-cell mitochondrial DNA genotyping and chromatin profiling, 2020, Nature Biotechnology
  • Hyperactivation of sympathetic nerves drives depletion of melanocyte stem cells, 2020, Nature

The scientist frequently publishes in venues such as bioRxiv (Cold Spring Harbor Laboratory), Nature, Cell, Zenodo (CERN European Organization for Nuclear Research), and Nature Communications.

Frequent co-authors of Jason D. Buenrostro include:

  • Sai Ma
  • Aviv Regev
  • Fabiana M. Duarte
  • Andrew Earl
  • Vinay K. Kartha

Best Publications

  • Transposition of native chromatin for fast and sensitive epigenomic profiling of open chromatin, DNA-binding proteins and nucleosome position

    Jason D Buenrostro;Paul G Giresi;Lisa C Zaba;Howard Y Chang

  • ATAC-seq: A Method for Assaying Chromatin Accessibility Genome-Wide

    Jason D. Buenrostro;Beijing Wu;Howard Y. Chang;William J. Greenleaf

  • Single-cell chromatin accessibility reveals principles of regulatory variation

    Jason D. Buenrostro;Beijing Wu;Ulrike M. Litzenburger;Dave Ruff

  • chromVAR: inferring transcription-factor-associated accessibility from single-cell epigenomic data

    Alicia N Schep;Beijing Wu;Jason D Buenrostro;William J Greenleaf

  • Lineage-specific and single-cell chromatin accessibility charts human hematopoiesis and leukemia evolution

    M Ryan Corces;Jason D Buenrostro;Jason D Buenrostro;Beijing Wu;Peyton G Greenside

  • Heritability enrichment of specifically expressed genes identifies disease-relevant tissues and cell types.

    Hilary K Finucane;Hilary K Finucane;Hilary K Finucane;Yakir A Reshef;Verneri Anttila;Verneri Anttila;Kamil Slowikowski;Kamil Slowikowski;Kamil Slowikowski

  • Chromatin Potential Identified by Shared Single-Cell Profiling of RNA and Chromatin.

    Sai Ma;Bing Zhang;Lindsay M. LaFave;Andrew S. Earl

  • Integrated Single-Cell Analysis Maps the Continuous Regulatory Landscape of Human Hematopoietic Differentiation

    Jason D. Buenrostro;Jason D. Buenrostro;M. Ryan Corces;Caleb A. Lareau;Caleb A. Lareau;Beijing Wu

  • The cis-Regulatory Atlas of the Mouse Immune System

    Hideyuki Yoshida;Caleb A. Lareau;Ricardo N. Ramirez;Samuel A. Rose

  • Deep learning and alignment of spatially resolved single-cell transcriptomes with Tangram.

    Tommaso Biancalani;Gabriele Scalia;Gabriele Scalia;Lorenzo Buffoni;Raghav Avasthi;Raghav Avasthi

  • Induction and transcriptional regulation of the co-inhibitory gene module in T cells

    Norio Chihara;Asaf Madi;Asaf Madi;Takaaki Kondo;Huiyuan Zhang

  • Lineage Tracing in Humans Enabled by Mitochondrial Mutations and Single-Cell Genomics.

    Leif S. Ludwig;Leif S. Ludwig;Caleb A. Lareau;Jacob C. Ulirsch;Elena Christian

  • Droplet-based combinatorial indexing for massive-scale single-cell chromatin accessibility.

    Caleb A Lareau;Fabiana M Duarte;Fabiana M Duarte;Jennifer G Chew;Vinay K Kartha;Vinay K Kartha

  • Pulling out the 1%: Whole-Genome Capture for the Targeted Enrichment of Ancient DNA Sequencing Libraries

    Meredith L. Carpenter;Jason D. Buenrostro;Cristina Valdiosera;Cristina Valdiosera;Hannes Schroeder

  • Structured nucleosome fingerprints enable high-resolution mapping of chromatin architecture within regulatory regions

    Alicia N. Schep;Jason D. Buenrostro;Sarah K. Denny;Katja Schwartz

  • Single-cell trajectories reconstruction, exploration and mapping of omics data with STREAM

    Huidong Chen;Luca Albergante;Luca Albergante;Jonathan Y. Hsu;Jonathan Y. Hsu;Caleb A. Lareau;Caleb A. Lareau

  • Assessment of computational methods for the analysis of single-cell ATAC-seq data

    Huidong Chen;Caleb Lareau;Caleb Lareau;Tommaso Andreani;Michael E. Vinyard

  • Quantitative analysis of RNA-protein interactions on a massively parallel array reveals biophysical and evolutionary landscapes.

    Jason D Buenrostro;Carlos L Araya;Lauren M Chircus;Curtis J Layton

  • ATAC-see reveals the accessible genome by transposase-mediated imaging and sequencing

    Xingqi Chen;Ying Shen;Will Draper;Jason D Buenrostro

  • Chromatin potential identified by shared single cell profiling of RNA and chromatin

    Sai Ma;Sai Ma;Sai Ma;Bing Zhang;Lindsay LaFave;Lindsay LaFave;Zachary Chiang

Frequent Co-Authors

William J. Greenleaf
William J. Greenleaf Stanford University
Aviv Regev
Aviv Regev Genentech
Howard Y. Chang
Howard Y. Chang Amgen (United States)
Martin J. Aryee
Martin J. Aryee Harvard University
Vijay G. Sankaran
Vijay G. Sankaran Harvard University
Jacob H. Hanna
Jacob H. Hanna Weizmann Institute of Science
Leonard I. Zon
Leonard I. Zon Harvard University
Hilary K. Finucane
Hilary K. Finucane Harvard University
John Bell
John Bell Queensland University of Technology
Joel N. Hirschhorn
Joel N. Hirschhorn Boston Children's Hospital

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