His primary areas of investigation include Cell biology, Induced pluripotent stem cell, Reprogramming, Embryonic stem cell and Genetics. His work deals with themes such as Chemokine, Molecular biology, Innate immune system and Epigenetics, which intersect with Cell biology. His Induced pluripotent stem cell research incorporates elements of Stem cell, Cellular differentiation and Somatic cell.
His Stem cell research includes themes of Induced stem cells and Embryoid body. His Reprogramming study incorporates themes from Cell potency and KLF4. His work on Immunology expands to the thematically related Embryonic stem cell.
Jacob H. Hanna mostly deals with Cell biology, Induced pluripotent stem cell, Reprogramming, Embryonic stem cell and Genetics. His Cell biology research incorporates themes from Chromatin, Cell, Epigenetics and Cellular differentiation. His Chromatin research integrates issues from Enhancer, Histone and Cell fate determination.
His Induced pluripotent stem cell study combines topics in areas such as Cell type and DNA methylation. His Reprogramming research includes elements of Somatic cell, Ectopic expression, SOX2, KLF4 and Molecular biology. The various areas that Jacob H. Hanna examines in his Embryonic stem cell study include Somatic cell nuclear transfer and MRNA modification.
Jacob H. Hanna spends much of his time researching Cell biology, Embryonic stem cell, Induced pluripotent stem cell, Stem cell and Messenger RNA. His work in Cell biology covers topics such as MRNA modification which are related to areas like Gametogenesis. His Embryonic stem cell research is multidisciplinary, relying on both Kinase, GSK-3, Cellular differentiation and Cell Cycle Gene.
His Induced pluripotent stem cell study combines topics from a wide range of disciplines, such as Reprogramming, Wnt signaling pathway, RBPJ and MAPK/ERK pathway. His research in Reprogramming intersects with topics in Epigenomics, DNA methylation, SOX2, Chromatin and Epigenetics. His Messenger RNA study also includes fields such as
His primary areas of investigation include Cell biology, Methylation, RNA, Messenger RNA and MRNA methylation. Specifically, his work in Cell biology is concerned with the study of Stem cell. Jacob H. Hanna combines subjects such as Nucleotide Motif, RNase P, Antibody and Computational biology with his study of Methylation.
His studies deal with areas such as Muscle hypertrophy and Methyltransferase as well as Messenger RNA. He has researched MRNA methylation in several fields, including Transgene, Homeostasis, Gene expression profiling, Molecular biology and Regulation of gene expression. His study in Embryonic stem cell is interdisciplinary in nature, drawing from both Blastomere, Blastocyst, Embryogenesis, Complementation and Transplantation.
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Histone H3K27ac separates active from poised enhancers and predicts developmental state
Menno P. Creyghton;Albert W. Cheng;G. Grant Welstead;Tristan G. Kooistra.
Proceedings of the National Academy of Sciences of the United States of America (2010)
Genome-scale DNA methylation maps of pluripotent and differentiated cells
Alexander Meissner;Tarjei S. Mikkelsen;Tarjei S. Mikkelsen;Hongcang Gu;Marius Wernig.
Nature (2008)
Epigenetic memory in induced pluripotent stem cells
K. Kim;A. Doi;B. Wen;K. Ng.
Nature (2010)
Treatment of sickle cell anemia mouse model with iPS cells generated from autologous skin.
Jacob Hanna;Marius Wernig;Styliani Markoulaki;Chiao-Wang Sun.
Science (2007)
Dissecting direct reprogramming through integrative genomic analysis
Tarjei S. Mikkelsen;Jacob Hanna;Xiaolan Zhang;Manching Ku.
Nature (2008)
Decidual NK cells regulate key developmental processes at the human fetal-maternal interface
Jacob Hanna;Debra Goldman-Wohl;Yaron Hamani;Inbal Avraham.
Nature Medicine (2006)
Direct cell reprogramming is a stochastic process amenable to acceleration
Jacob Hanna;Krishanu Saha;Bernardo Pando;Jeroen van Zon.
Nature (2009)
Direct Reprogramming of Terminally Differentiated Mature B Lymphocytes to Pluripotency
Jacob Hanna;Styliani Markoulaki;Patrick Schorderet;Bryce W. Carey.
Cell (2008)
Derivation of novel human ground state naive pluripotent stem cells
Ohad Gafni;Leehee Weinberger;Abed AlFatah Mansour;Yair S. Manor.
Nature (2013)
Human embryonic stem cells with biological and epigenetic characteristics similar to those of mouse ESCs
Jacob Hanna;Albert W. Cheng;Krishanu Saha;Jongpil Kim.
Proceedings of the National Academy of Sciences of the United States of America (2010)
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