D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 56 Citations 8,950 239 World Ranking 6992 National Ranking 35

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Enzyme
  • Cancer

The scientist’s investigation covers issues in Cell culture, Molecular biology, Cancer research, Chinese hamster ovary cell and Gene expression profiling. His Cell culture research is multidisciplinary, incorporating elements of Biotechnology, In vitro, Cell growth and Cell biology. His Molecular biology study combines topics from a wide range of disciplines, such as Transferrin, Biochemistry, DNA, Difference gel electrophoresis and Squamous carcinoma.

His study in Cancer research is interdisciplinary in nature, drawing from both Cancer, Breast cancer, Tyrosine-kinase inhibitor, Receptor and Pharmacology. The concepts of his Chinese hamster ovary cell study are interwoven with issues in Gene expression, Computational biology and Recombinant DNA. His Gene expression profiling research incorporates elements of Microarray, DNA microarray, microRNA and Gene knockdown.

His most cited work include:

  • Epidermal growth factor receptor as a potential therapeutic target in triple-negative breast cancer (240 citations)
  • Enhancement of chemotherapeutic drug toxicity to human tumour cells in vitro by a subset of non-steroidal anti-inflammatory drugs (NSAIDs) (231 citations)
  • Prognostic importance of survivin in breast cancer (212 citations)

What are the main themes of his work throughout his whole career to date?

Martin Clynes focuses on Cell culture, Cancer research, Molecular biology, Cell biology and Chinese hamster ovary cell. His research investigates the connection with Cell culture and areas like Gene expression profiling which intersect with concerns in Microarray. His work deals with themes such as Cancer, Breast cancer, Pancreatic cancer and Immunology, which intersect with Cancer research.

His work carried out in the field of Cancer brings together such families of science as Oncology and Pathology. Martin Clynes interconnects Cell and Secretion in the investigation of issues within Cell biology. Proteomics is closely connected to Proteome in his research, which is encompassed under the umbrella topic of Chinese hamster ovary cell.

He most often published in these fields:

  • Cell culture (24.13%)
  • Cancer research (22.67%)
  • Molecular biology (20.93%)

What were the highlights of his more recent work (between 2015-2021)?

  • Chinese hamster ovary cell (16.57%)
  • Cell biology (19.48%)
  • Cell culture (24.13%)

In recent papers he was focusing on the following fields of study:

His primary scientific interests are in Chinese hamster ovary cell, Cell biology, Cell culture, Cancer research and Proteome. In his study, Ubiquitin is inextricably linked to Cell growth, which falls within the broad field of Chinese hamster ovary cell. His Cell biology research is multidisciplinary, incorporating elements of Phenotype, Oxidative phosphorylation, microRNA and Messenger RNA.

The various areas that Martin Clynes examines in his Cell culture study include Molecular biology, Food science, Micronutrient and Intracellular. His Molecular biology study combines topics from a wide range of disciplines, such as Liposome, Gene expression and Serum free media. The study incorporates disciplines such as Immunohistochemistry and Cancer, Metastasis, Pancreatic cancer in addition to Cancer research.

Between 2015 and 2021, his most popular works were:

  • Proteomic differences in recombinant CHO cells producing two similar antibody fragments. (20 citations)
  • Filter-Aided Sample Preparation (FASP) for Improved Proteome Analysis of Recombinant Chinese Hamster Ovary Cells. (17 citations)
  • Process-relevant concentrations of the leachable bDtBPP impact negatively on CHO cell production characteristics. (15 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Enzyme
  • Cancer

Martin Clynes mostly deals with Chinese hamster ovary cell, Cell biology, Proteome, Recombinant DNA and Proteomics. His Chinese hamster ovary cell study results in a more complete grasp of Cell culture. His work deals with themes such as Biotechnology and Gene expression, which intersect with Cell culture.

In Cell biology, Martin Clynes works on issues like Messenger RNA, which are connected to Gene ontology, Microarray, Caco-2 and Mirna expression. His work carried out in the field of Recombinant DNA brings together such families of science as Food science and Antioxidant. While the research belongs to areas of microRNA, Martin Clynes spends his time largely on the problem of In silico, intersecting his research to questions surrounding Cancer research.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Prognostic importance of survivin in breast cancer

S M Kennedy;L O'Driscoll;R Purcell;N Fitz-simons.
British Journal of Cancer (2003)

381 Citations

Epidermal growth factor receptor as a potential therapeutic target in triple-negative breast cancer

B. Corkery;J. Crown;M. Clynes;N. O'Donovan.
Annals of Oncology (2009)

367 Citations

Enhancement of chemotherapeutic drug toxicity to human tumour cells in vitro by a subset of non-steroidal anti-inflammatory drugs (NSAIDs)

C.P. Duffy;C.J. Elliott;R.A. O'Connor;M.M. Heenan.
European Journal of Cancer (1998)

291 Citations

Correlating transcriptional networks to breast cancer survival: a large-scale coexpression analysis

Colin Clarke;Stephen F. Madden;Padraig Doolan;Sinead T. Aherne.
Carcinogenesis (2013)

245 Citations

α-1 Antitrypsin regulates human neutrophil chemotaxis induced by soluble immune complexes and IL-8.

David A. Bergin;Emer P. Reeves;Paula Meleady;Michael Henry.
Journal of Clinical Investigation (2010)

243 Citations

Comparison of 5 microplate colorimetric assays for in vitro cytotoxicity testing and cell proliferation assays

Angela Martin;Martin Clynes.
Cytotechnology (1993)

189 Citations

Proliferation control strategies to improve productivity and survival during CHO based production culture: A summary of recent methods employed and the effects of proliferation control in product secreting CHO cell lines

Niraj Kumar;Patrick Gammell;Martin Clynes.
Cytotechnology (2007)

181 Citations

In vitro Development of Chemotherapy and Targeted Therapy Drug-Resistant Cancer Cell Lines: A Practical Guide with Case Studies.

Martina McDermott;Alex J. Eustace;Steven Busschots;Laura Breen.
Frontiers in Oncology (2014)

179 Citations

Proteomic approaches for serum biomarker discovery in cancer.

Priyanka Maurya;Paula Meleady;Paul Dowling;Martin Clynes.
Anticancer Research (2007)

165 Citations

Pre-exposure to yeast protects larvae of Galleria mellonella from a subsequent lethal infection by Candida albicans and is mediated by the increased expression of antimicrobial peptides.

David Bergin;Lisa Murphy;Joanne Keenan;Martin Clynes.
Microbes and Infection (2006)

153 Citations

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