Martin Clynes

Overview

Best Publications

• Correlating transcriptional networks to breast cancer survival: a large-scale coexpression analysis

  Colin Clarke;Stephen F. Madden;Padraig Doolan;Sinead T. Aherne

  530
  Citations

• Epidermal growth factor receptor as a potential therapeutic target in triple-negative breast cancer

  B. Corkery;J. Crown;M. Clynes;N. O'Donovan

  459
  Citations

• Prognostic importance of survivin in breast cancer

  S M Kennedy;L O'Driscoll;R Purcell;N Fitz-simons

  397
  Citations

• Enhancement of chemotherapeutic drug toxicity to human tumour cells in vitro by a subset of non-steroidal anti-inflammatory drugs (NSAIDs)

  C.P. Duffy;C.J. Elliott;R.A. O'Connor;M.M. Heenan

  320
  Citations

• α-1 Antitrypsin regulates human neutrophil chemotaxis induced by soluble immune complexes and IL-8.

  David A. Bergin;Emer P. Reeves;Paula Meleady;Michael Henry

  318
  Citations

• In vitro Development of Chemotherapy and Targeted Therapy Drug-Resistant Cancer Cell Lines: A Practical Guide with Case Studies.

  Martina McDermott;Alex J. Eustace;Steven Busschots;Laura Breen

  294
  Citations

• Bone Disease in Multiple Myeloma: Pathophysiology and Management

  Abdul Hameed;Jennifer J. Brady;Paul Dowling;Martin Clynes

  223
  Citations

• Proliferation control strategies to improve productivity and survival during CHO based production culture: A summary of recent methods employed and the effects of proliferation control in product secreting CHO cell lines

  Niraj Kumar;Patrick Gammell;Martin Clynes

  209
  Citations

• Pre-exposure to yeast protects larvae of Galleria mellonella from a subsequent lethal infection by Candida albicans and is mediated by the increased expression of antimicrobial peptides.

  David Bergin;Lisa Murphy;Joanne Keenan;Martin Clynes

  202
  Citations

• Comparison of 5 microplate colorimetric assays for in vitro cytotoxicity testing and cell proliferation assays

  Angela Martin;Martin Clynes

  199
  Citations

• A neutrophil intrinsic impairment affecting Rab27a and degranulation in cystic fibrosis is corrected by CFTR potentiator therapy.

  Kerstin Pohl;Elaine Hayes;Joanne Keenan;Michael Henry

  182
  Citations

• Proteomic approaches for serum biomarker discovery in cancer.

  Priyanka Maurya;Paula Meleady;Paul Dowling;Martin Clynes

  174
  Citations

• Analysis of the saliva proteome from patients with head and neck squamous cell carcinoma reveals differences in abundance levels of proteins associated with tumour progression and metastasis

  Paul Dowling;Robert Wormald;Paula Meleady;Michael Henry

  168
  Citations

• Conditioned media from cell lines: A complementary model to clinical specimens for the discovery of disease-specific biomarkers

  Paul Dowling;Martin Clynes

  166
  Citations

• Survivin: role in normal cells and in pathological conditions.

  L. O'Driscoll;R. Linehan;M. Clynes

  165
  Citations

• Biomarkers and Multiple Drug Resistance in Breast Cancer

  L O'Driscoll;M Clynes

  159
  Citations

• BreastMark : An Integrated Approach to Mining Publicly Available Transcriptomic Datasets Relating to Breast Cancer Outcome

  Stephen F Madden;Colin Clarke;Patricia Gaule;Sinead T Aherne

  158
  Citations

• MiRNA-29a regulates the expression of numerous proteins and reduces the invasiveness and proliferation of human carcinoma cell lines

  M.K. Muniyappa;Paul Dowling;M. Henry;Paula Meleady

  149
  Citations

• Acid phosphatase: Endpoint for in vitro toxicity tests

  Angela Martin;Martin Clynes

  142
  Citations

• The 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors, simvastatin, lovastatin and mevastatin inhibit proliferation and invasion of melanoma cells

  Sharon A Glynn;Dermot O'Sullivan;Alex J Eustace;Martin Clynes

  140
  Citations