Michael Devereux

Overview

Best Publications

• Synthesis, X-ray crystal structures and biomimetic and anticancer activities of novel copper(II)benzoate complexes incorporating 2-(4'-thiazolyl)benzimidazole (thiabendazole), 2-(2-pyridyl)benzimidazole and 1,10-phenanthroline as chelating nitrogen donor ligands.

  Michael Devereux;Denis O Shea;Andrew Kellett;Andrew Kellett;Malachy McCann

  264
  Citations

• Copper(II) Complexes of Salicylic Acid Combining Superoxide Dismutase Mimetic Properties with DNA Binding and Cleaving Capabilities Display Promising Chemotherapeutic Potential with Fast Acting in Vitro Cytotoxicity against Cisplatin Sensitive and Resistant Cancer Cell Lines

  Mark O'Connor;Andrew Kellett;Malachy McCann;Georgina Rosair

  223
  Citations

• Mode of anti-fungal activity of 1,10-phenanthroline and its Cu(II), Mn(II) and Ag(I) complexes.

  Barry Coyle;Kevin Kavanagh;Malachy McCann;Michael Devereux

  205
  Citations

• Synthesis, catalase, superoxide dismutase and antitumour activities of copper(II) carboxylate complexes incorporating benzimidazole, 1,10-phenanthroline and bipyridine ligands : X-ray crystal structures of [Cu (BZA )2(bipy ) (H2O ) ], [Cu(SalH)2(BZDH)2] and [Cu (CH3COO )2(5,6 -DMBZDH )2] (SalH2 = salicylic acid; BZAH = benzoic acid; BZDH = benzimidazole and 5,6-DMBZDH = 5,6-dimethylbenzimidazole)

  Michael Devereux;Denis O’Shea;Mark O’Connor;Helen Grehan

  197
  Citations

• Synthesis and anti- Candida activity of copper(II) and manganese(II) carboxylate complexes: X-ray crystal structures of [Cu(sal)(bipy)]·C2H5OH·H2O and [Cu(norb)(phen)2]·6.5H2O (salH2=salicylic acid; norbH2=cis-5-norbornene-endo-2,3-dicarboxylic acid; bipy=2,2′-bipyridine; phen=1,10-phenanthroline)

  Majella Geraghty;Vivienne Sheridan;Malachy McCann;Michael Devereux

  185
  Citations

• In vitro anti-tumour and cyto-selective effects of coumarin-3-carboxylic acid and three of its hydroxylated derivatives, along with their silver-based complexes, using human epithelial carcinoma cell lines.

  Bhumika Thati;Andy Noble;Bernadette S. Creaven;Maureen Walsh

  162
  Citations

• Synthesis and catalytic activity of manganese(II) complexes of heterocyclic carboxylic acids: X-ray crystal structures of [Mn(pyr)2]n, [Mn(dipic)(bipy)2]·4.5H2O and [Mn(chedam)(bipy)]·H2O (pyr=2-pyrazinecarboxylic acid; dipic=pyridine-2,6-dicarboxylic acid; chedam=chelidamic acid(4-hydroxypyridine-2,6-dicarboxylic acid); bipy=2,2-bipyridine)

  Michael Devereux;Malachy McCann;Vanessa Leon;Vickie McKee

  160
  Citations

• Insights into the mode of action of the anti-Candida activity of 1,10-phenanthroline and its metal chelates.

  Malachy McCann;Majella Geraghty;Michael Devereux;Denis O'Shea

  143
  Citations

• Induction of apoptosis in yeast and mammalian cells by exposure to 1,10-phenanthroline metal complexes.

  Barry Coyle;Paula Kinsella;Malachy McCann;Michael Devereux

  142
  Citations

• Copper(II) complexes of coumarin-derived Schiff bases and their anti- Candida activity

  Bernadette S. Creaven;Michael Devereux;Dariusz Karcz;Andrew Kellett

  138
  Citations

• In vitro anti-tumour effect of 1,10-phenanthroline-5,6-dione (phendione), [Cu(phendione)3](ClO4)2.4H2O and [Ag(phendione)2]ClO4 using human epithelial cell lines.

  Carol Deegan;Barry Coyle;Barry Coyle;Malachy McCann;Malachy McCann;Michael Devereux;Michael Devereux

  126
  Citations

• Syntheses and X-ray crystal structures of cis-[Mn(bipy)2Cl2] · 2H2O · EtOH and cis-[Mn(phen)2Cl2] (bipy = 2,2′-bipyridine; phen = 1,10-phenanthroline); catalysts for the disproportionation of hydrogen peroxide

  Sebastian McCann;Malachy McCann;Michael T. Casey;Maura Jackman

  124
  Citations

• ‘Silver bullets’ in antimicrobial chemotherapy: Synthesis, characterisation and biological screening of some new Ag(I)-containing imidazole complexes

  Raymond Rowan;Theresa Tallon;Anita M. Sheahan;Robert Curran

  120
  Citations

• Synthesis and X-ray crystal structure of [Ag(phendio)2]ClO4 (phendio = 1,10-phenanthroline-5,6-dione) and its effects on fungal and mammalian cells

  Malachy McCann;Barry Coyle;Sinead McKay;Paul McCormack

  119
  Citations

• In vitro and in vivo studies into the biological activities of 1,10-phenanthroline, 1,10-phenanthroline-5,6-dione and its copper(II) and silver(I) complexes

  Malachy McCann;André L. S. Santos;Bianca A. da Silva;Maria Teresa V. Romanos

  118
  Citations

• Bis-phenanthroline copper(II) phthalate complexes are potent in vitro antitumour agents with ‘self-activating’ metallo-nuclease and DNA binding properties

  Andrew Kellett;Mark O'Connor;Malachy McCann;Mary McNamara

  116
  Citations

• Synthesis, antimicrobial activity and chemotherapeutic potential of inorganic derivatives of 2-(4'-thiazolyl)benzimidazole[thiabendazole]: X-ray crystal structures of [Cu(TBZH)2Cl]Cl.H2O.EtOH and TBZH2NO3 (TBZH=thiabendazole).

  Michael Devereux;Malachy McCann;Denis O Shea;Rachel Kelly

  114
  Citations

• Synthesis, X-ray crystal structure, anti-fungal and anti-cancer activity of [Ag2(NH3)2(salH)2] (salH2= salicylic acid)

  Barry Coyle;Malachy McCann;Kevin Kavanagh;Michael Devereux

  109
  Citations

• Quinolin-2(1H)-one-triazole derived Schiff bases and their Cu(II) and Zn(II) complexes: Possible new therapeutic agents

  Bernadette S. Creaven;Michael Devereux;Agnieszka Foltyn;Siobhán McClean

  105
  Citations

• Water-soluble bis(1,10-phenanthroline) Octanedioate Cu2+ and Mn2+ Complexes with Unprecedented Nano and Picomolar in Vitro Cytotoxicity: Promising Leads for Chemotherapeutic Drug Development

  Andrew Kellett;Mark O'Connor;Malachy McCann;Orla Howe

  98
  Citations

• Role of cell cycle events and apoptosis in mediating the anti-cancer activity of a silver(I) complex of 4-hydroxy-3-nitro-coumarin-bis(phenanthroline) in human malignant cancer cells.

  Bhumika Thati;Andy Noble;Bernadette S. Creaven;Maureen Walsh

  93
  Citations