World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
64
Citations
13149
World Ranking
9782
National Ranking
4292

Research.com Recognitions

  • 2010 - Fellow of the Indian National Academy of Engineering (INAE)
  • 2010 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Kelvin H. Lee is affiliated with the University of Delaware in the United States and has a scholarly profile encompassing extensive research in biochemistry, genetics, molecular biology, and medicine. The core of their work is situated in molecular biology with additional focus on radiology, nuclear medicine, imaging, genetics, oncology, and biomedical engineering. Their studies span multiple topics including viral infectious diseases and gene expression in insects, protein purification and stability, monoclonal and polyclonal antibodies research, virus-based gene therapy, CRISPR and genetic engineering, CAR-T cell therapy, and biomedical and engineering education.

Lee has authored numerous papers published in several scientific venues with Biotechnology and Bioengineering being the most frequent, accounting for 23 publications. Other notable journals include Clinical Lymphoma Myeloma & Leukemia, Biotechnology Journal, PDA Journal of Pharmaceutical Science and Technology, and Journal of Biology and Life Science.

Their recent representative papers include:

  • Biopharmaceutical Manufacturing: Historical Perspectives and Future Directions, 2022, Annual Review of Chemical and Biomolecular Engineering
  • Antibody transcytosis across brain endothelial-like cells occurs nonspecifically and independent of FcRn, 2020, Scientific Reports
  • Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome, 2020, Biotechnology and Bioengineering
  • End-to-end collaboration to transform biopharmaceutical development and manufacturing, 2021, Biotechnology and Bioengineering
  • Systematic identification of safe harbor regions in the CHO genome through a comprehensive epigenome analysis, 2020, Biotechnology and Bioengineering

Frequent collaborators in Lee's work include Leila H. Choe, Lie Min, Abraham M. Lenhoff, Nathaniel K. Hamaker, and William Hilliard, indicating active engagement in collaborative research networks.

Kelvin H. Lee has been recognized by professional societies as a Fellow of the American Association for the Advancement of Science (AAAS) and a Fellow of the Indian National Academy of Engineering (INAE), both awarded in 2010.

Best Publications

  • The genomic sequence of the Chinese hamster ovary (CHO)-K1 cell line

    Xun Xu;Harish Nagarajan;Nathan E Lewis;Shengkai Pan

  • The 14-3-3 brain protein in cerebrospinal fluid as a marker for transmissible spongiform encephalopathies.

    Gary Hsich;Kimbra Kenney;Clarence J. Gibbs;Kelvin H. Lee

  • 8-plex quantitation of changes in cerebrospinal fluid protein expression in subjects undergoing intravenous immunoglobulin treatment for Alzheimer's disease.

    Leila Choe;Mark D'Ascenzo;Norman R. Relkin;Darryl Pappin

  • Shotgun proteomics using the iTRAQ isobaric tags.

    Kunal Aggarwal;Leila H. Choe;Kelvin H. Lee

  • Totally asymmetric exclusion process with extended objects: a model for protein synthesis.

    Leah B. Shaw;R. K. P. Zia;Kelvin H. Lee

  • The statistical mechanics of complex signaling networks: nerve growth factor signaling.

    K S Brown;K S Brown;C C Hill;C C Hill;G A Calero;G A Calero;C R Myers

  • Effect of remote ischaemic conditioning on clinical outcomes in patients with acute myocardial infarction (CONDI-2/ERIC-PPCI): a single-blind randomised controlled trial.

    Derek J Hausenloy;Rajesh K Kharbanda;Ulla Kristine Møller;Manish Ramlall;Manish Ramlall

  • Cerebrospinal fluid proteomic biomarkers for Alzheimer's disease

    Erin J. Finehout;Zsofia Franck;Leila H. Choe;Norman Relkin

  • Applications of affinity chromatography in proteomics.

    Wen-Chien Lee;Kelvin H Lee

  • The statistical mechanics of complex signaling networks : nerve growth factor signaling

    Kevin S. Brown;Colin C. Hill;Guillermo A. Calero;Kelvin H. Lee

  • Knockout of a difficult-to-remove CHO host cell protein, lipoprotein lipase, for improved polysorbate stability in monoclonal antibody formulations.

    Josephine Chiu;Kristin N. Valente;Nicholas E. Levy;Lie Min

  • Identification and characterization of host cell protein product-associated impurities in monoclonal antibody bioprocessing.

    Nicholas E. Levy;Kristin N. Valente;Kristin N. Valente;Leila H. Choe;Leila H. Choe;Kelvin H. Lee;Kelvin H. Lee

  • Inverse metabolic engineering: a strategy for directed genetic engineering of useful phenotypes

    James E. Bailey;Adriana Sburlati;Vassily Hatzimanikatis;Kelvin Lee

  • Proteomics: a technology-driven and technology-limited discovery science

    Kelvin H Lee

  • Dynamical analysis of gene networks requires both mRNA and protein expression information

    Vassily Hatzimanikatis;Kelvin H. Lee

  • A comparison of the consistency of proteome quantitation using two-dimensional electrophoresis and shotgun isobaric tagging in Escherichia coli cells.

    Leila H. Choe;Kunal Aggarwal;Zsofia Franck;Kelvin H. Lee

  • Insights into the relation between mRNA and protein expression patterns: I. Theoretical considerations.

    Amit Mehra;Kelvin H. Lee;Vassily Hatzimanikatis

  • Genomic sequencing and analysis of a Chinese hamster ovary cell line using Illumina sequencing technology.

    Stephanie Hammond;Stephanie Hammond;Jeffrey C Swanberg;Jeffrey C Swanberg;Mihailo Kaplarevic;Kelvin H Lee;Kelvin H Lee

  • Proteomics: Theoretical and Experimental Considerations

    Vassily Hatzimanikatis;Leila H. Choe;Kelvin H. Lee

  • Tuning and Predicting Mesh Size and Protein Release from Step Growth Hydrogels

    Matthew S. Rehmann;Kelsi M. Skeens;Prathamesh M. Kharkar;Eden M. Ford

Frequent Co-Authors

Abraham M. Lenhoff
Abraham M. Lenhoff University of Delaware
Vassily Hatzimanikatis
Vassily Hatzimanikatis École Polytechnique Fédérale de Lausanne
James P. Sethna
James P. Sethna Cornell University
Michael J. Betenbaugh
Michael J. Betenbaugh Johns Hopkins University
Nathan E. Lewis
Nathan E. Lewis University of California, San Diego
Wilfred Chen
Wilfred Chen University of Delaware
Harold G. Craighead
Harold G. Craighead Cornell University
Jonathan D. Dinman
Jonathan D. Dinman University of Maryland, College Park
Michael L. Shuler
Michael L. Shuler Cornell University
Jennifer L. West
Jennifer L. West University of Virginia

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