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Michael J. Betenbaugh

Michael J. Betenbaugh

D-Index & Metrics

Biology and Biochemistry

D-Index
82
Citations
19790
World Ranking
3764
National Ranking
1862

Research.com Recognitions

  • 2002 - Fellow of the Indian National Academy of Engineering (INAE)

Overview

Michael J. Betenbaugh is a researcher affiliated with Johns Hopkins University in the United States. Their work spans several fields within biochemistry, genetics, molecular biology, and medicine, with a focus on molecular biology and infectious diseases. The body of research reflects interdisciplinary expertise combining biomedical engineering and genetic engineering approaches.

Betenbaugh's research has been published across a variety of scientific journals and venues. Key venues where their contributions appear frequently include:

  • Biotechnology and Bioengineering
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Metabolic Engineering
  • Current Opinion in Biotechnology
  • Journal of Clinical Investigation

Their publications cover a wide range of topics related to viral infectious diseases and gene expression in insects, SARS-CoV-2 and COVID-19 research, microbial metabolic engineering and bioproduction, as well as protein purification and stability. Specific areas of study also include virus-based gene therapy research and CRISPR genetic engineering techniques.

Frequent collaborators within Betenbaugh's research community include:

  • Andrew Pekosz
  • Sabra L. Klein
  • Harnish Mukesh Naik
  • Venkata Gayatri Dhara
  • Swetha Kumar

Some recent notable research papers by Betenbaugh include:

  • "Sex, age, and hospitalization drive antibody responses in a COVID-19 convalescent plasma donor population," 2020, published in Journal of Clinical Investigation
  • "COVID-19 Serology at Population Scale: SARS-CoV-2-Specific Antibody Responses in Saliva," 2020, Journal of Clinical Microbiology
  • "Genome-scale reconstructions of the mammalian secretory pathway predict metabolic costs and limitations of protein secretion," 2020, Nature Communications
  • "Sex Differences in Lung Imaging and SARS-CoV-2 Antibody Responses in a COVID-19 Golden Syrian Hamster Model," 2021, mBio
  • "Durable SARS-CoV-2 B cell immunity after mild or severe disease," 2021, Journal of Clinical Investigation

Betenbaugh's research activity is documented extensively in biochemistry, genetics, and molecular biology with a total of 133 publications in these fields. Additionally, 60 publications fall within medicine, showing their engagement with applied clinical and biomedical topics.

The scientist has contributed to subfields including:

  • Molecular Biology
  • Infectious Diseases
  • Biomedical Engineering
  • Genetics
  • Radiology, Nuclear Medicine and Imaging

Throughout their career, Michael J. Betenbaugh received recognition such as being named a Fellow of the Indian National Academy of Engineering (INAE) in 2002.

Best Publications

  • The genomic sequence of the Chinese hamster ovary (CHO)-K1 cell line

    Xun Xu;Harish Nagarajan;Nathan E Lewis;Shengkai Pan

  • A green light for engineered algae: redirecting metabolism to fuel a biotechnology revolution

    Julian N Rosenberg;George A Oyler;Loy Wilkinson;Michael J Betenbaugh

  • Sex, age, and hospitalization drive antibody responses in a COVID-19 convalescent plasma donor population.

    Sabra L. Klein;Andrew Pekosz;Han Sol Park;Rebecca L. Ursin

  • Genomic landscapes of Chinese hamster ovary cell lines as revealed by the Cricetulus griseus draft genome

    Nathan E Lewis;Xin Liu;Yuxiang Li;Harish Nagarajan

  • The effect of mixotrophy on microalgal growth, lipid content, and expression levels of three pathway genes in Chlorella sorokiniana

    Minxi Wan;Minxi Wan;Peng Liu;Jinlan Xia;Jinlan Xia;Julian N. Rosenberg

  • A critical analysis of paddlewheel-driven raceway ponds for algal biofuel production at commercial scales

    Jonathan N. Rogers;Julian N. Rosenberg;Bernardo J. Guzman;Victor H. Oh

  • Life and death in mammalian cell culture: strategies for apoptosis inhibition.

    Nilou Arden;Michael J Betenbaugh

  • Determination of nucleotides and sugar nucleotides involved in protein glycosylation by high-performance anion-exchange chromatography: sugar nucleotide contents in cultured insect cells and mammalian cells.

    Noboru Tomiya;Eric Ailor;Shawn M. Lawrence;Michael J. Betenbaugh

  • COVID-19 serology at population scale: SARS-CoV-2-specific antibody responses in saliva.

    Nora Pisanic;Pranay R. Randad;Kate Kruczynski;Yukari C. Manabe

  • A Consensus Genome-scale Reconstruction of Chinese Hamster Ovary Cell Metabolism.

    Hooman Hefzi;Kok Siong Ang;Michael Hanscho;Aarash Bordbar

  • Controlling N-linked glycan site occupancy.

    Jullian Jones;Sharon S. Krag;Michael J. Betenbaugh

  • Accelerating genome editing in CHO cells using CRISPR Cas9 and CRISPy, a web-based target finding tool.

    Carlotta Ronda;Lasse Ebdrup Pedersen;Henning Gram Hansen;Thomas Beuchert Kallehauge

  • The effects of alternative pretreatment strategies on anaerobic digestion and methane production from different algal strains.

    Pavlo Bohutskyi;Michael J. Betenbaugh;Edward J. Bouwer

  • Design and Production of Bispecific Antibodies.

    Qiong Wang;Yiqun Chen;Jaeyoung Park;Xiao Liu

  • A mathematical model of N-linked glycosylation.

    Frederick J. Krambeck;Michael J. Betenbaugh

  • Proteomic Analysis of Chinese Hamster Ovary Cells

    Deniz Baycin-Hizal;David L. Tabb;Raghothama Chaerkady;Lily Chen

  • Differential N-glycan patterns of secreted and intracellular IgG produced in Trichoplusia ni cells.

    Tsu-An Hsu;Noriko Takahashi;Yoshinori Tsukamoto;Koichi Kato

  • The emerging CHO systems biology era: harnessing the 'omics revolution for biotechnology.

    Helene Faustrup Kildegaard;Deniz Baycin-Hizal;Nathan E Lewis;Nathan E Lewis;Michael J Betenbaugh;Michael J Betenbaugh

  • Comparing N-glycan processing in mammalian cell lines to native and engineered lepidopteran insect cell lines.

    Noboru Tomiya;Someet Narang;Yuan C Lee;Michael J Betenbaugh

  • Modifying secretion and post-translational processing in insect cells.

    Eric Ailor;Michael J Betenbaugh

Frequent Co-Authors

Joseph Shiloach
Joseph Shiloach National Institutes of Health
Hui Zhang
Hui Zhang Johns Hopkins University
Yuan C. Lee
Yuan C. Lee Johns Hopkins University
Nathan E. Lewis
Nathan E. Lewis University of California, San Diego
Edward J. Bouwer
Edward J. Bouwer Johns Hopkins University
Karsten Zengler
Karsten Zengler University of California, San Diego
J. Marie Hardwick
J. Marie Hardwick Johns Hopkins University
Kevin J. Yarema
Kevin J. Yarema Johns Hopkins University
Andrew Pekosz
Andrew Pekosz Johns Hopkins University
Oliver Laeyendecker
Oliver Laeyendecker Johns Hopkins University

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