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D-Index & Metrics

Biology and Biochemistry

D-Index
81
Citations
18850
World Ranking
3959
National Ranking
1951

Overview

Joseph Shiloach is affiliated with the National Institutes of Health in the United States. Their research primarily spans the fields of Biochemistry, Genetics and Molecular Biology, and Medicine.

The main subfields of study include Molecular Biology, Genetics, Immunology, Infectious Diseases, and Public Health, Environmental and Occupational Health.

The scientist's work addresses several key topics such as:

  • Viral Infectious Diseases and Gene Expression in Insects
  • Bacterial Genetics and Biotechnology
  • Virus-based gene therapy research
  • CRISPR and Genetic Engineering
  • Microbial Metabolic Engineering and Bioproduction
  • Immune Response and Inflammation
  • Protein Structure and Dynamics

Notable recent papers authored or co-authored by Joseph Shiloach include:

  • "Affecting HEK293 Cell Growth and Production Performance by Modifying the Expression of Specific Genes," 2021, published in Cells
  • "A novel knock out strategy to enhance recombinant protein expression in Escherichia coli," 2020, published in Microbial Cell Factories
  • "Iron availability enhances the cellular energetics of aerobic Escherichia coli cultures while upregulating anaerobic respiratory chains," 2022, published in New Biotechnology
  • "Linking Phospho-Gonadotropin Regulated Testicular RNA Helicase (GRTH/DDX25) to Histone Ubiquitination and Acetylation Essential for Spermatid Development During Spermiogenesis," 2020, published in Frontiers in Cell and Developmental Biology
  • "Knockout of the caspase 8-associated protein 2 gene improves recombinant protein expression in HEK293 cells through up-regulation of the cyclin-dependent kinase inhibitor 2A gene," 2020, published in Biotechnology and Bioengineering

Frequent co-authors collaborating with Joseph Shiloach are:

  • Ashish K. Sharma
  • Laura Abaandou
  • David N. Quan
  • Je-Nie Phue
  • Eric Anderson

The scientist has published across several venues, with a record of publications in:

  • Cells
  • Microbial Cell Factories
  • New Biotechnology
  • Frontiers in Cell and Developmental Biology
  • International Journal of Molecular Sciences

Best Publications

  • Structural basis of toll-like receptor 3 signaling with double-stranded RNA.

    Lin Liu;Istvan Botos;Yan Wang;Joshua N. Leonard

  • Structure of the agonist-bound neurotensin receptor

    Jim F. White;Nicholas Noinaj;Yoko Shibata;Yoko Shibata;James Love

  • The efficacy of a Salmonella typhi Vi conjugate vaccine in two-to-five-year-old children.

    F Y Lin;V A Ho;H B Khiem;D D Trach

  • Growing E. coli to high cell density--a historical perspective on method development.

    Joseph Shiloach;Rephael Fass

  • CHARACTERIZATION OF THE IMITATION SWITCH SUBFAMILY OF ATP-DEPENDENT CHROMATIN-REMODELING FACTORS IN SACCHAROMYCES CEREVISIAE

    Toshio Tsukiyama;Jeffrey Palmer;Carolyn C. Landel;Joseph Shiloach

  • The molecular structure of the Toll-like receptor 3 ligand-binding domain

    Jessica K. Bell;Istvan Botos;Pamela R. Hall;Janine Askins

  • Evolutionary origins of vertebrate hormones: substances similar to mammalian insulins are native to unicellular eukaryotes

    D Le Roith;J Shiloach;J Roth;M A Lesniak

  • The evolutionary origins of hormones, neurotransmitters, and other extracellular chemical messengers: implications for mammalian biology.

    Jesse Roth;Derek LeRoith;Joseph Shiloach;James L. Rosenzweig

  • Agonist and Antagonist Properties of Calmodulin Fragments

    D L Newton;M D Oldewurtel;M H Krinks;J Shiloach

  • Enzyme replacement therapy in Gaucher's disease: large-scale purification of glucocerebrosidase suitable for human administration.

    F S Furbish;H E Blair;J Shiloach;P G Pentchev

  • Synthesis and immunologic properties in mice of vaccines composed of Staphylococcus aureus type 5 and type 8 capsular polysaccharides conjugated to Pseudomonas aeruginosa exotoxin A.

    A Fattom;R Schneerson;S C Szu;W F Vann

  • Corticotropin and β-endorphin-like materials are native to unicellular organisms

    D. LeRoith;A. S. Liotta;J. Roth;J. Shiloach

  • Poly(γ-d-glutamic acid) protein conjugates induce IgG antibodies in mice to the capsule of Bacillus anthracis: A potential addition to the anthrax vaccine

    Rachel Schneerson;Joanna Kubler-Kielb;Teh-Yung Liu;Zhong-Dong Dai

  • Dimerization of the class A G protein-coupled neurotensin receptor NTS1 alters G protein interaction

    Jim F. White;Justin Grodnitzky;John M. Louis;Loc B. Trinh

  • Effect of glucose supply strategy on acetate accumulation, growth, and recombinant protein production by Escherichia coli BL21 (λDE3) and Escherichia coli JM109

    J. Shiloach;J. Kaufman;A. S. Guillard;R. Fass

  • Development of an improved vaccine for anthrax

    Stephen H. Leppla;John B. Robbins;Rachel Schneerson;Joseph Shiloach

  • Glucose metabolism at high density growth of E-coli B and E-coli K: Differences in metabolic pathways are responsible for efficient glucose utilization in E-coli B as determined by microarrays and northern blot analyses

    Je-Nie Phue;Santosh B. Noronha;Ritabrata Hattacharyya;Alan J. Wolfe

  • Laboratory and preliminary clinical characterization of Vi capsular polysaccharide-protein conjugate vaccines.

    S C Szu;D N Taylor;A C Trofa;J D Clements

  • Treatment of Uveitis by Oral Administration of Retinal Antigens: Results of a Phase I/II Randomized Masked Trial

    Robert B. Nussenblatt;Igal Gery;Howard L. Weiner;Frederick L. Ferris

  • Production, Purification and Immunogenicity of a Malaria Transmission-Blocking Vaccine Candidate: TBV25H Expressed in Yeast and Purified Using Nickel-NTA Agarose

    David C. Kaslow;Joseph Shiloach

Frequent Co-Authors

Michael J. Betenbaugh
Michael J. Betenbaugh Johns Hopkins University
John B. Robbins
John B. Robbins National Institutes of Health
Rachel Schneerson
Rachel Schneerson National Institutes of Health
Derek LeRoith
Derek LeRoith Icahn School of Medicine at Mount Sinai
William E. Bentley
William E. Bentley University of Maryland, College Park
Jesse Roth
Jesse Roth National Institutes of Health
Stephen H. Leppla
Stephen H. Leppla National Institutes of Health
Konstantinos Konstantopoulos
Konstantinos Konstantopoulos Johns Hopkins University
Michael W. Berns
Michael W. Berns University of California, Irvine
William E. Biddison
William E. Biddison National Institutes of Health

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