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Chemistry

D-Index
60
Citations
19512
World Ranking
9538
National Ranking
2680

Research.com Recognitions

  • 2012 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

John P. Wolfe is affiliated with the University of Michigan-Ann Arbor in the United States. Their research primarily spans the field of Chemistry, with a strong focus on Organic Chemistry. The work also intersects with Biomedical Engineering, Education, Cancer Research, and Safety Research.

Their recent publications demonstrate a focus on palladium-catalyzed reactions and alkene difunctionalization. Notable papers include:

  • "Pd-Catalyzed C−C, C−N, and C−O Bond-Forming Difunctionalization Reactions of Alkenes Bearing Tethered Aryl/Alkenyl Triflates" (2020, Israel Journal of Chemistry)
  • "Pd-Catalyzed Alkene Diamination Reactions with O-Benzoylhydroxylamine Electrophiles: Evidence Supporting a Pd(II/IV) Catalytic Cycle, the Role of 2,4-Pentanedione Derivatives as Ligands, and Expanded Substrate Scope" (2021, The Journal of Organic Chemistry)
  • "Regiodivergent Palladium-Catalyzed Alkene Difunctionalization Reactions for the Construction of Methylene Cyclobutanes and Methylene Cyclopentanes" (2022, Organic Letters)
  • "Influence of CUREs on STEM retention depends on demographic identities" (2023, Journal of Microbiology and Biology Education)
  • "Synthesis of 2-Cyanomethyl Indane Derivatives via Pd-Catalyzed Alkene Difunctionalization Reactions of Alkyl Nitriles" (2023, Organic Letters)

These works highlight topics such as catalytic C-H functionalization methods, catalytic cross-coupling reactions, catalytic alkyne reactions, asymmetric synthesis and catalysis, and synthesis combined with biological activity. The scientist's research also involves studies related to nonlinear optical materials.

Frequent collaborators include Evan C. Bornowski, Alma R. Perez, James H. Shepich, Derick R. White, and Jessica Hatt. Their partnership reflects ongoing research projects and coauthored publications.

Publication venues where Wolfe regularly contributes include:

  • Organic Letters
  • Israel Journal of Chemistry
  • The Journal of Organic Chemistry
  • Journal of Microbiology and Biology Education
  • ACS Materials Letters

John P. Wolfe's research activity is principally in organic chemistry reactions catalyzed by palladium, including their mechanistic and synthetic aspects. Their contributions extend to education and biomedical research as well, reflecting interdisciplinary interests.

Wolfe was recognized as a Fellow of the American Association for the Advancement of Science (AAAS) in 2012.

Best Publications

  • Rational Development of Practical Catalysts for Aromatic Carbon−Nitrogen Bond Formation

    John P. Wolfe;Seble Wagaw;§ and Jean-François Marcoux;Stephen L. Buchwald

  • Highly Active Palladium Catalysts for Suzuki Coupling Reactions

    John P. Wolfe;Robert A. Singer;Bryant H. Yang;Stephen L. Buchwald

  • A Highly Active Catalyst for Palladium-Catalyzed Cross-Coupling Reactions: Room-Temperature Suzuki Couplings and Amination of Unactivated Aryl Chlorides

    David W. Old;John P. Wolfe;Stephen L. Buchwald

  • Simple, Efficient Catalyst System for the Palladium-Catalyzed Amination of Aryl Chlorides, Bromides, and Triflates

    John P. Wolfe;Hiroshi Tomori;Joseph P. Sadighi;Jingjun Yin

  • An Improved Catalyst System for Aromatic Carbon−Nitrogen Bond Formation: The Possible Involvement of Bis(Phosphine) Palladium Complexes as Key Intermediates

    John P. Wolfe;Seble Wagaw;Stephen L. Buchwald

  • A Highly Active Catalyst for the Room-Temperature Amination and Suzuki Coupling of Aryl Chlorides.

    John P. Wolfe;Stephen L. Buchwald

  • Novel Electron-Rich Bulky Phosphine Ligands Facilitate the Palladium-Catalyzed Preparation of Diaryl Ethers

    Attila Aranyos;David W. Old;Ayumu Kiyomori;John P. Wolfe

  • Scope and Limitations of the Pd/BINAP-Catalyzed Amination of Aryl Bromides

    John P. Wolfe;Stephen L. Buchwald

  • An Ammonia Equivalent for the Palladium-Catalyzed Amination of Aryl Halides and Triflates

    John P Wolfe;Jens Åhman;Joseph P Sadighi;Robert A Singer

  • Recent Advances in the Stereoselective Synthesis of Tetrahydrofurans.

    John P. Wolfe;Michael B. Hay

  • Synthesis of Oxygen Heterocycles via a Palladium-Catalyzed C−O Bond-Forming Reaction

    Michael Palucki;John P. Wolfe;Stephen L. Buchwald

  • Asymmetric Arylation of Ketone Enolates

    Jens Åhman;John P. Wolfe;Malisa V. Troutman;Michael Palucki

  • Intramolecular palladium-catalyzed aryl amination and aryl amidation

    John P. Wolfe;Roger A. Rennels;Stephen L. Buchwald

  • Stereoselective synthesis of saturated heterocycles via palladium-catalyzed alkene carboetherification and carboamination reactions

    John P. Wolfe

  • Palladium-Catalyzed Amination of Aryl Triflates

    John P. Wolfe;Stephen L. Buchwald

  • Palladium-Catalyzed Carboetherification and Carboamination Reactions of γ-Hydroxy- and γ-Aminoalkenes for the Synthesis of Tetrahydrofurans and Pyrrolidines

    John P. Wolfe

  • Palladium-Catalyzed Intermolecular Carbon−Oxygen Bond Formation: A New Synthesis of Aryl Ethers

    Michael Palucki;John P. Wolfe;Stephen L. Buchwald

  • PALLADIUM-CATALYZED AMINATION OF ARYL IODIDES

    John P. Wolfe;Stephen L. Buchwald

  • Asymmetric palladium-catalyzed carboamination reactions for the synthesis of enantiomerically enriched 2-(arylmethyl)- and 2-(alkenylmethyl)pyrrolidines.

    Duy N. Mai;John P. Wolfe

  • Palladium‐Catalyzed Synthesis of N‐Aryl Pyrrolidines from γ‐(N‐Arylamino) Alkenes: Evidence for Chemoselective Alkene Insertion into Pd ? N Bonds

    Joshua E. Ney;John P. Wolfe

  • Ligands for metals and improved metal-catalyzed processes based thereon

    Stephen L. Buchwald;David W. Old;John P. Wolfe;Michael Palucki

Frequent Co-Authors

Larry E. Overman
Larry E. Overman University of California, Irvine
Jeff W. Kampf
Jeff W. Kampf University of Michigan–Ann Arbor
Julius Rebek
Julius Rebek Scripps Research Institute
Gary A. Molander
Gary A. Molander University of Pennsylvania
Mark M. Banaszak Holl
Mark M. Banaszak Holl Monash University
Kerri A. Pratt
Kerri A. Pratt University of Michigan–Ann Arbor
Johanna L. Mathieu
Johanna L. Mathieu University of Michigan–Ann Arbor
Scott Backhaus
Scott Backhaus Los Alamos National Laboratory
Ian A. Hiskens
Ian A. Hiskens University of Michigan–Ann Arbor

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