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Molecular Biology

D-Index
63
Citations
23834
World Ranking
1774
National Ranking
53

Research.com Recognitions

  • 2016 - Fellow of the Royal Society of Canada Academy of Science

Overview

Paul Lasko is affiliated with McGill University in Canada and specializes in the field of Biochemistry, Genetics and Molecular Biology. Their research portfolio includes 58 publications primarily focused on molecular biology, genetics, and cell biology, with additional work in plant science and cellular and molecular neuroscience.

The scientist's main research topics encompass:

  • Genomics and Rare Diseases
  • RNA Research and Splicing
  • CRISPR and Genetic Engineering
  • Cellular Mechanics and Interactions
  • Genetics and Neurodevelopmental Disorders
  • Chromosomal and Genetic Variations
  • Genomics and Chromatin Dynamics

Paul Lasko has contributed to numerous scholarly articles published in a variety of scientific journals. Frequent publication venues include:

  • Faculty Opinions - Post-Publication Peer Review of the Biomedical Literature
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Molecular Cell
  • Molecular Genetics and Metabolism
  • Wiley Interdisciplinary Reviews - RNA

Selected recent publications of Paul Lasko are:

  • Patterning the Drosophila embryo: A paradigm for RNA-based developmental genetic regulation, 2020, Wiley Interdisciplinary Reviews - RNA
  • Histone H3.3 K27M and K36M mutations de-repress transposable elements through perturbation of antagonistic chromatin marks, 2021, Molecular Cell
  • The Undiagnosed Diseases Network International: Five years and more!, 2020, Molecular Genetics and Metabolism
  • The piRNA-pathway factor FKBP6 is essential for spermatogenesis but dispensable for control of meiotic LINE-1 expression in humans, 2022, The American Journal of Human Genetics
  • Ectoderm to mesoderm transition by down-regulation of actomyosin contractility, 2021, PLoS Biology

They have collaborated frequently with several scientists, including:

  • François Fagotto (5 publications)
  • Greco Hernández (4 publications)
  • Hong Han (3 publications)
  • Julie A. Brill (3 publications)
  • David B. Rozema (3 publications)

Paul Lasko was recognized as a Fellow of the Royal Society of Canada in 2016 by the Academy of Science.

Best Publications

  • The genome sequence of Drosophila melanogaster

    M. D. Adams;S. E. Celniker;R. A. Holt;C. A. Evans

  • Birth of the D-E-A-D box.

    Patrick Linder;Paul F. Lasko;Michael Ashburner;Pascale Leroy

  • The product of the Drosophila gene vasa is very similar to eukaryotic initiation factor-4A

    Paul F. Lasko;Michael Ashburner

  • Autism-related deficits via dysregulated eIF4E-dependent translational control

    Christos G. Gkogkas;Arkady Khoutorsky;Israeli Ran;Emmanouil Rampakakis

  • The International Human Epigenome Consortium: A Blueprint for Scientific Collaboration and Discovery

    Hendrik G. Stunnenberg;Martin Hirst

  • Posterior localization of vasa protein correlates with, but is not sufficient for, pole cell development.

    Paul F. Lasko;Michael Ashburner

  • Localization of vasa protein to the Drosophila pole plasm is independent of its RNA-binding and helicase activities

    Lu Liang;William Diehl-Jones;Paul Lasko

  • Translational regulation and RNA localization in Drosophila oocytes and embryos.

    Oona Johnstone;Paul Lasko

  • mRNA helicases:the tacticians of translational control

    Armen Parsyan;Yuri Svitkin;David Shahbazian;Christos Gkogkas

  • vasa is required for GURKEN accumulation in the oocyte, and is involved in oocyte differentiation and germline cyst development

    Sylvia Styhler;Akira Nakamura;Andrew Swan;Beat Suter

  • Germline development in vertebrates and invertebrates.

    E. E. Saffman;P. Lasko

  • A new paradigm for translational control: inhibition via 5'-3' mRNA tethering by Bicoid and the eIF4E cognate 4EHP.

    Park F. Cho;Francis Poulin;Yoon Andrew Cho-Park;Ian B. Cho-Park

  • Translational repressor bruno plays multiple roles in development and is widely conserved

    Philippa J. Webster;Lu Liang;Lu Liang;Celeste A. Berg;Paul Lasko

  • The translational inhibitor 4E-BP is an effector of PI(3)K/Akt signalling and cell growth in Drosophila.

    Mathieu Miron;Javier Verdú;Pascal E.D. Lachance;Morris J. Birnbaum;Morris J. Birnbaum

  • Cytoplasmic Polyadenylation Element Binding Proteins in Development, Health, and Disease

    Maria Ivshina;Paul Lasko;Joel D. Richter

  • Self-Association of the Single-KH-Domain Family Members Sam68, GRP33, GLD-1, and Qk1: Role of the KH Domain

    Taiping Chen;Bassam B. Damaj;Constance Herrera;Paul Lasko

  • Translational control in cellular and developmental processes

    Jian Kong;Paul Lasko

  • Phosphorylation of eukaryotic translation initiation factor 4E is critical for growth.

    Pascal E. D. Lachance;Mathieu Miron;Brian Raught;Nahum Sonenberg

  • Drosophila Pgc protein inhibits P-TEFb recruitment to chromatin in primordial germ cells.

    Kazuko Hanyu-Nakamura;Hiroko Sonobe-Nojima;Akie Tanigawa;Paul Lasko

  • Requirement for a noncoding RNA in Drosophila polar granules for germ cell establishment.

    Akira Nakamura;Reiko Amikura;Masanori Mukai;Satoru Kobayashi

Frequent Co-Authors

Nahum Sonenberg
Nahum Sonenberg McGill University
Kym M. Boycott
Kym M. Boycott Children's Hospital of Eastern Ontario
Norbert Perrimon
Norbert Perrimon Harvard University
Michael Ashburner
Michael Ashburner University of Cambridge
Christopher P. Austin
Christopher P. Austin National Institutes of Health
Tony Roscioli
Tony Roscioli University of New South Wales
Satoru Miyano
Satoru Miyano Tokyo Medical and Dental University
Eric D. Green
Eric D. Green National Institutes of Health
John S. Mattick
John S. Mattick University of New South Wales
Hanns Lochmüller
Hanns Lochmüller University of Freiburg

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