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Chemistry
Canada
2026

D-Index & Metrics

Chemistry

D-Index
115
Citations
44254
World Ranking
640
National Ranking
11

Research.com Recognitions

  • 2026 - Research.com Chemistry in Canada Leader Award
  • 2025 - Research.com Chemistry in Canada Leader Award
  • 2023 - Research.com Chemistry in Canada Leader Award
  • 2022 - Research.com Chemistry in Canada Leader Award
  • 2013 - Chemical Institute of Canada Medal
  • 2001 - Fellow of the Royal Society of Canada Academy of Science
  • 1994 - Rutherford Memorial Medal in Chemistry, Royal Society of Canada
  • 1991 - Fellow of Alfred P. Sloan Foundation

Overview

Mark Lautens is affiliated with the University of Toronto in Canada and specializes in the field of Chemistry, with a strong focus on Organic Chemistry. Their research contributions span several subfields including Inorganic Chemistry, Pharmaceutical Science, Molecular Biology, and Plant Science.

Their work covers a range of main topics in chemical catalysis and reaction mechanisms, such as:

  • Catalytic C-H Functionalization Methods
  • Catalytic Cross-Coupling Reactions
  • Asymmetric Hydrogenation and Catalysis
  • Cyclopropane Reaction Mechanisms
  • Synthesis and Catalytic Reactions
  • Catalytic Alkyne Reactions
  • Radical Photochemical Reactions

Mark Lautens has published extensively, with significant numbers of articles appearing in prominent journals. Frequent publication venues include:

  • Organic Letters (14 publications)
  • ACS Catalysis (12 publications)
  • Synfacts (12 publications)
  • Angewandte Chemie International Edition (11 publications)
  • Angewandte Chemie (9 publications)

Among the recent papers authored or co-authored by Mark Lautens are:

  • "Copper-Catalyzed Borylative Difunctionalization of π-Systems," ACS Catalysis, 2020
  • "Metal-Catalyzed Approaches toward the Oxindole Core," Accounts of Chemical Research, 2020
  • "Cobalt-Catalyzed Enantioselective Hydroarylation of 1,6-Enynes," Journal of the American Chemical Society, 2020
  • "Catalytic asymmetric transformations of oxa- and azabicyclic alkenes," Chemical Society Reviews, 2021
  • "Nickel-Catalyzed Enantioselective Carbamoyl Iodination: A Surrogate for Carbamoyl Iodides," ACS Catalysis, 2020

Collaborations have been a consistent component of their research output, often working with colleagues including:

  • Bijan Mirabi
  • Austin D. Marchese
  • Andrew Whyte
  • Ramon Arora
  • Jonathan Bajohr

Throughout their career, Mark Lautens has been recognized with several awards, such as:

  • Chemical Institute of Canada Medal (2013)
  • Fellow of the Royal Society of Canada, Academy of Science (2001)
  • Rutherford Memorial Medal in Chemistry, Royal Society of Canada (1994)
  • Fellow of Alfred P. Sloan Foundation (1991)

Best Publications

  • Aryl-aryl bond formation by transition-metal-catalyzed direct arylation.

    Dino Alberico;Mark E. Scott;Mark Lautens

  • Transition Metal-Mediated Cycloaddition Reactions

    Mark Lautens;Wolfgang Klute;William Tam

  • Rhodium-catalyzed carbon-carbon bond forming reactions of organometallic compounds.

    Keith Fagnou;Mark Lautens

  • Secondary alkyl halides in transition-metal-catalyzed cross-coupling reactions.

    Alena Rudolph;Mark Lautens

  • Construction of nitrogen-containing heterocycles by C-H bond functionalization.

    Praew Thansandote;Mark Lautens

  • Modern Transition-Metal-Catalyzed Carbon–Halogen Bond Formation

    David A. Petrone;Juntao Ye;Mark Lautens

  • Halide effects in transition metal catalysis.

    Keith Fagnou;Mark Lautens

  • Palladium-catalysed norbornene-mediated C-H functionalization of arenes.

    Juntao Ye;Mark Lautens

  • Transition metal-catalyzed enantioselective ring-opening reactions of oxabicyclic alkenes.

    Mark Lautens;Keith Fagnou;Sheldon Hiebert

  • A route to annulated indoles via a palladium-catalyzed tandem alkylation/direct arylation reaction.

    Cyril Bressy;Dino Alberico;Mark Lautens

  • Total Synthesis of Bryostatin 2

    David A. Evans;Percy H. Carter;Erick M. Carreira;André B. Charette

  • Synthesis in the key of Catellani: norbornene-mediated ortho C-H functionalization.

    Andrew Martins;Brian Mariampillai;Mark Lautens

  • A New Route to Fused Aromatic Compounds by Using a Palladium-Catalyzed Alkylation - Alkenylation Sequence This work was supported by the NSERC (Canada) and the University of Toronto. S.P. thanks the Fondation Bettencourt - Schueller for a postdoctoral fellowship.

    M Lautens;S Piguel

  • New frontiers in asymmetric catalysis

    Koichi Mikami;Mark Lautens

  • Palladium‐Catalyzed Domino Direct Arylation/N‐Arylation: Convenient Synthesis of Phenanthridines

    David A. Candito;Mark Lautens

  • Cyclization via isomerization: a palladium(2+)-catalyzed carbocyclization of 1,6-enynes to 1,3- and 1,4-dienes

    Barry M. Trost;Mark Lautens

  • Efficient synthesis of benzothiophenes by an unusual palladium-catalyzed vinylic C-S coupling.

    Christopher S. Bryan;Julia A. Braunger;Mark Lautens

  • Copper-Catalyzed Borylative Difunctionalization of π-Systems

    Andrew Whyte;Alexa Torelli;Bijan Mirabi;Anji Zhang

  • Metal-Catalyzed Hydrostannations

    Nicholas D. Smith;John Mancuso;Mark Lautens

  • A Convergent Synthesis of Polysubstituted Aromatic Nitriles via Palladium-Catalyzed C−H Functionalization

    Brian Mariampillai;Julien Alliot;Mengzhou Li;Mark Lautens

  • Rhodium-catalyzed coupling reactions of arylboronic acids to olefins in aqueous media.

    Mark Lautens;Amélie Roy;Koichiro Fukuoka;Keith Fagnou

  • Rhodium-Catalyzed Asymmetric Ring Opening of Oxabicyclic Alkenes with Organoboronic Acids

    Mark Lautens;Chris Dockendorff;and Keith Fagnou;Adrianna Malicki

Frequent Co-Authors

Barry M. Trost
Barry M. Trost Stanford University
Shaodan Ma
Shaodan Ma University of Macau
Lei Yu
Lei Yu Yangzhou University
Keith Fagnou
Keith Fagnou University of Ottawa
Matthieu Schapira
Matthieu Schapira University of Toronto
Jean-Luc Renaud
Jean-Luc Renaud Université de Caen Normandie
Tomislav Rovis
Tomislav Rovis Columbia University
Franziska Schoenebeck
Franziska Schoenebeck RWTH Aachen University
André B. Charette
André B. Charette University of Montreal

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