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D-Index & Metrics

Biology and Biochemistry

D-Index
69
Citations
14560
World Ranking
7521
National Ranking
3422

Research.com Recognitions

  • 1981 - Fellow of John Simon Guggenheim Memorial Foundation

Overview

David H. Alpers is affiliated with Washington University in St. Louis in the United States. Their research primarily focuses on the field of Medicine, with contributions spanning subfields such as Pharmacology, Public Health, Environmental and Occupational Health, Surgery, Epidemiology, and Ecology.

The scientist's recent publications reflect diverse interests including liver disease, drug metabolism, and nutritional studies. Notable papers authored or coauthored by David H. Alpers include the following:

  • "Health outcomes associated with vegetarian diets: An umbrella review of systematic reviews and meta-analyses" (2020) published in Clinical Nutrition
  • "Vitamin B12 absorption and malabsorption" (2022) published in Vitamins and hormones
  • "Clinical Pattern of Tolvaptan-Associated Liver Injury in Trial Participants With Autosomal Dominant Polycystic Kidney Disease (ADPKD): An Analysis of Pivotal Clinical Trials" (2022) published in American Journal of Kidney Diseases
  • "Effect of changes in metabolic enzymes and transporters on drug metabolism in the context of liver disease: Impact on pharmacokinetics and drug-drug interactions" (2023) published in British Journal of Clinical Pharmacology
  • "Drug-Induced Liver Injury in the Elderly: Consensus Statements and Recommendations from the IQ-DILI Initiative" (2024) published in Drug Safety

Frequent coauthors collaborating with David H. Alpers include:

  • James H. Lewis
  • Jean-Louis Guéant
  • Eric Cohen
  • Raúl J. Andrade
  • Don C. Rockey

The scientist often publishes in venues such as:

  • Drug Safety
  • UNC Libraries
  • Clinical Nutrition
  • Vitamins and hormones
  • British Journal of Clinical Pharmacology

The work of David H. Alpers encompasses research on several main topics, including:

  • Liver Disease Diagnosis and Treatment
  • Drug-Induced Hepatotoxicity and Protection
  • Pharmacogenetics and Drug Metabolism
  • Agriculture Sustainability and Environmental Impact
  • Obesity, Physical Activity, Diet
  • Nutritional Studies and Diet
  • Genetic and Kidney Cyst Diseases

David H. Alpers has received recognition through awards such as becoming a Fellow of the John Simon Guggenheim Memorial Foundation in 1981.

Best Publications

  • Clindamycin-Associated Colitis: A Prospective Study

    Francis J. Tedesco;Robert W. Barton;David H. Alpers

  • Nutrition support in clinical practice: review of published data and recommendations for future research directions. Summary of a conference sponsored by the National Institutes of Health, American Society for Parenteral and Enteral Nutrition, and American Society for Clinical Nutrition.

    S Klein;J Kinney;K Jeejeebhoy;D Alpers

  • The nucleotide sequence of rat liver fatty acid binding protein mRNA.

    J I Gordon;D H Alpers;R K Ockner;A W Strauss

  • Tissue specific expression and developmental regulation of two genes coding for rat fatty acid binding proteins.

    J I Gordon;N Elshourbagy;J B Lowe;W S Liao

  • Cloning of a cDNA encoding rat intestinal fatty acid binding protein

    David H. Alpers;Arnold W. Strauss;Robert K. Ockner;Nathan M. Bass

  • Regulation of the biosynthesis of two distinct fatty acid-binding proteins in rat liver and intestine. Influences of sex difference and of clofibrate.

    N M Bass;J A Manning;R K Ockner;J I Gordon

  • Accelerated fat absorption in intestinal alkaline phosphatase knockout mice.

    Sonoko Narisawa;Lei Huang;Arata Iwasaki;Hideaki Hasegawa

  • Caco-2 cells express a combination of colonocyte and enterocyte phenotypes.

    M.J. Engle;G.S. Goetz;D.H. Alpers

  • Effect of proteolytic enzymes on the binding of cobalamin to R protein and intrinsic factor. In vitro evidence that a failure to partially degrade R protein is responsible for cobalamin malabsorption in pancreatic insufficiency.

    Robert H. Allen;Bellur Seetharam;Elaine Podell;David H. Alpers

  • Oleic acid stimulation of apolipoprotein B secretion from HepG2 and Caco-2 cells occurs post-transcriptionally.

    James B. Moberly;Thomas G. Cole;David H. Alpers;Gustav Schonfeld

  • Do life events or depression exacerbate inflammatory bowel disease? A prospective study.

    Carol S. North;David H. Alpers;John E. Helzer;Edward L. Spitznagel

  • The primary translation product of rat intestinal apolipoprotein A-I mRNA is an unusual preproprotein.

    J I Gordon;D P Smith;R Andy;D H Alpers

  • A Study of the Association Between Crohn's Disease and Psychiatric Illness

    John E. Helzer;Sabah Chammas;Charles C. Norland;Wayne A. Stillings

  • Clinical Pattern of Tolvaptan-Associated Liver Injury in Subjects with Autosomal Dominant Polycystic Kidney Disease: Analysis of Clinical Trials Database

    Paul B. Watkins;James H. Lewis;Neil Kaplowitz;David H. Alpers

  • The possible role of pancreatic proteases in the turnover of intestinal brush border proteins.

    David H. Alpers;Francis J. Tedesco

  • The Relation of Ulcerative Colitis to Psychiatric Factors: A Review of Findings and Methods

    Carol S. North;Ray E. Clouse;Edward L. Spitznagel;David H. Alpers

  • Intestinal apoproteins during fat absorption.

    G. Schonfeld;E. Bell;David Alpers

  • Protein synthesis in intestinal mucosa: the effect of route of administration of precursor amino acids.

    David H. Alpers

  • A controlled study of the association between ulcerative colitis and psychiatric diagnoses.

    John E. Helzer;Wayne A. Stillings;Sabah Chammas;Charles C. Norland

  • Relationship of functional gastrointestinal disorders and psychiatric disorders: Implications for treatment

    Carol S North;Barry A Hong;David H Alpers

Frequent Co-Authors

William F. Stenson
William F. Stenson Washington University in St. Louis
Ray E. Clouse
Ray E. Clouse Washington University in St. Louis
Carol S. North
Carol S. North The University of Texas Southwestern Medical Center
Samuel Klein
Samuel Klein Washington University in St. Louis
Arnold W. Strauss
Arnold W. Strauss Cincinnati Children's Hospital Medical Center
Edward L. Spitznagel
Edward L. Spitznagel Washington University in St. Louis
Louis V. Avioli
Louis V. Avioli Washington University in St. Louis
Graeme P. Young
Graeme P. Young Flinders University
Jeffrey I. Gordon
Jeffrey I. Gordon Washington University in St. Louis
Dennis M. Bier
Dennis M. Bier Baylor College of Medicine

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